ObjectiveTo investigate the current situation of domestic registry studies, and to provide basis for future research.MethodsWorld Health Organization (WHO) registration platform, ClinicalTrials.gov registration platform and other registration platforms were searched to collect the registered registration studies in Mainland China from inception to July 31st, 2018. Two researchers collected and collated data, analyzed by descriptive statistical methods, and then python-igraph package in Python 3.5 was used to draw the network diagram.ResultsA total of 247 studies were retrieved, mainly for disease registry and pharmaceutical product registry. Cohort and case-series were the principally study design. The research focused on chronic diseases such as cardiovascular and cerebrovascular diseases, and research sites were based on the economically developed area, for example, Beijing, Shanghai and Guangdong. The network diagram of study design and disease system shows that cohort research design is widely used in the nervous system and circulatory system; the network diagram of the research sites and disease system found that Beijing mainly studied circulatory and nervous system diseases, Shanghai mainly studied circulatory system diseases, and Guangdong relatively studied more on nervous system and urinary system diseases.ConclusionThe increasing number of registry studies in China reflects the importance of long-term outcome assessment of diseases.
Objective To explore a new teaching mode relying on the new media platform, aiming to stimulate residency standardized trainees’ interest in learning theories related to gynecology outpatient surgery, improve practical operation skills, and achieve better teaching effects. Methods The residency standardized trainees who rotate in the gynecology outpatient of West China Second University Hospital, Sichuan University between July 2021 and June 2022 were selected. According to the random number table method, the trainees were divided into the control group (using the traditional teaching mode) and the intervention group (using the teaching mode of combining the flipped classroom and simulated teaching relying on the new media platform). The assessment results, teacher evaluation, trainees self-evaluation and teaching satisfaction of the two groups were compared and analyzed. Results A total of 118 trainees were enrolled, 59 in each group. There was no significant difference in gender, age, years of training and education level between the two groups (P>0.05). The total scores of evaluation scores (87.59±4.54 vs. 85.17±3.70), teachers’ evaluation (87.05±3.79 vs. 85.14±3.75), and trainees’ self-evaluation (87.81±4.41 vs. 85.54±3.96) of trainees in the intervention group were better than those in the control group, and the differences were statistically significant (P<0.05). The clinical thinking ability [teachers’ evaluation (24.49±1.62 vs. 23.22±2.05), trainees’ self-evaluation (25.25±1.99 vs. 23.97±2.27) and operation skills [teachers’ evaluation (37.05±1.58 vs. 36.10±1.99), trainees’ self-evaluation (36.75±2.73 vs. 35.66±2.56)] of trainees in the intervention group were better than those in the control group, and the differences were statistically significant (P<0.05). The satisfaction rate of the trainees in the intervention group was 98.3%, and that of the trainees in the control group was 93.2%. The teaching satisfaction of the intervention group was better than that of the control group (P<0.05). Conclusion The teaching mode of combining flipped classroom and simulated teaching relying on the new media platform has effectively stimulated residency standardized trainees’ learning interest in gynecological outpatient surgery, improved trainees’ clinical practice ability, improved teaching satisfaction, achieved good teaching results, and can be promoted as a new teaching mode.
ObjectiveTo summarize the research progress of tissue engineered bile duct in recent years.MethodsThis paper summarized recently-published papers related to tissue-engineered bile duct on in vitro test platform, scaffold materials, acquisition methods of seed cells, and in vivo repair effectiveness after the fusion of seed cells and materials, in an attempt to review the basic and clinical application studies of tissue-engineered bile duct.ResultsTissue-engineered bile duct had been developing rapidly. At present, great progress had been made in the fields of in vitro test platform, scaffold materials, seed cells, and repair effectiveness in animal models. However, further study was still needed in terms of its clinical application. The external bile duct platform included 3D printing and biological simulation; in the aspect of scaffold material, apart from the progress of various artificial materials, acellular matrix was introduced; the selection of seed cells included the induction and differentiation of bile duct-derived stem cells, human bone marrow mesenchymal stem cells (hMSCs), hepatic oval cell (HOC), pluripotent stem cells (PSCs), and other stem cells; animal models of tissue-engineered bile ducts had also achieved good results in animals such as pigs and dogs.ConclusionThe development of tissue-engineered bile duct will promote the progress of fundamental in vitro studies on extrahepatic biliary tract diseases, thus introducing new options to the clinical treatment of extrahepatic biliary tract injuries.
ObjectiveTo study the current situation of WeChat public platforms in 15 provincial hospitals in Hubei Province.MethodsWe searched the website of National Health Commission of the People’s Republic of China, website of Health Commission of Hubei Province, and the official website of each hospital. The WeChat public platforms of 15 provincial hospitals in Hubei Province was determined as the research object. Samples were taken in July, 2019 and the observation cut-off point was on October 30, 2019. All the contents released by the WeChat public platforms in July were counted. Literature research, descriptive statistics, content analysis, WeChat transmission index analysis, observation indicators and other methods were used for analysis and research.ResultsAmong the 15 hospitals, 14 hospitals (93.3%) had established 20 WeChat public platforms, and 5 hospitals (33.3%) simultaneously opened service accounts and subscription accounts. The functions of serving the patients’ medical experience mainly included identity registration, appointment registration, information inquiry, patient feedback, intelligent medical guidance, etc. WeChat tweets were mainly divided into 38.0% of popular medical science, 11.4% of hospital news, 15.8% of medical service, 13.6% of party and government construction, and 21.2% of patient interaction. The monthly push times of 6 WeChat public platforms (30.0%) were less than 4 times. The monthly original rate of WeChat public platform tweets was 16.3%. Among the top 10 WeChat public platforms in the WeChat communication index, 8 (80.0%) were service accounts. There was a big gap in the dissemination effect of tweets.ConclusionsThe WeChat public platform of provincial hospitals in Hubei Province has problems such as single type of WeChat public platform, imperfect service functions, unreasonable tweets frequency, insufficient originality of tweets, and uneven communication effects. It is necessary to enrich platform types, improve platform functions, ameliorate the frequency of tweets, improve the originality of tweets, and pay attention to communication effects.
The full-cycle rehabilitation management for orthopedic patients can solve the problems of standardization, systematization, and whole process of orthopaedic rehabilitation management, and prevent short-term and long-term complications. The First Affiliated Hospital of Sun Yat-sen University has constructed a full-cycle rehabilitation management platform for orthopedic patients based on multi-source data since 2023, including six modules: multi-source data collection and integration module, intelligent individualized rehabilitation program setting module, and visual rehabilitation training module, and has explored a digitally-driven full-cycle rehabilitation management mode for orthopedic patients. This article elaborates on the platform’s functional design and implementation, full-cycle rehabilitation management mode, and application effectiveness, in order to provide a reference for promoting the integration of mobile health and orthopedic patient rehabilitation practice.
Objective To explore the feasibility and clinical effect of management of children with epilepsy based on WeChat platform. Methods The WeChat platform for management of children epilepsy was designed according to the idea of the management of chronic diseases. The objective and control groups were investigated by the case-control study. Eighty children with epilepsy who took part in the platform were served as the experimental group. At the same time, 80 children with epilepsy who did not take part in the platform were served as the control group. The questionnaire of basic conditions and users’ perceived acceptance and usage of the platform designed by ourselves were used to collect related information. Results Sixty parents of children with epilepsy continuously used the platform and among them 48 parents (80.0%) had high satisfaction degree of the platform. The factors which affected the satisfaction degree of the platform among basic conditions included whether the users were busy, the comprehensive degree of knowledge about epilepsy before they took part in the study and the degree of taking medicine on time(P<0.05).There were no differences in satisfaction degree among different children sex, residence, parents’ sex, education level, approaches and willingness of knowledge acquisition(P>0.05). Follow-up of 60 children with epilepsy who had been in the platform for 6 months showed total effective rate was 96.7%, while the total effective rate of the control group was 81.4%. Conclusions Management of children with epilepsy based on WeChat platform is feasible and well accepted. Not only does it contribute to standard long-term management of children epilepsy and health education, but also it improves the efficiency of clinical treatment. It is a new way of the management of children with epilepsy.
In order to promote the effective development of hospital day surgery mode, a construction method of information management platform that meets the characteristics of day surgery mode is presented. By analyzing the business process of the day surgery mode, the system architecture of the information platform is given; according to the difficulty of the surgical scheduling, the two-stage surgical scheduling algorithm based on the ranking theory is given; by analyzing the day surgery data statistically, a multi-angle surgical index analysis module is provided. The information management of the day surgery mode has been realized, and the work efficiency has been improved. A reasonable day surgery information platform construction can help to optimize the daytime surgical procedure and promote the smooth development of day surgery.
In the context of informatization and digitization, medical big data has become crucial for promoting medical research and technological innovation, posing unprecedented challenges to the construction and operation of big data research supercomputing platforms. This article systematically elaborates on the construction plan of the scientific research supercomputing platform of the West China Biomedical Big Data Center of Sichuan University, as well as the management and service models that support data research. It also compares the scale and operation of existing scientific research supercomputing platforms at home and abroad, providing a reference for the construction and management of medical big data scientific research supercomputing platforms in other institutions.
In order to promote the openness, transparency and standardization of clinical trials, improve the scientific and reliability of results, and reserve the manpower, material, and financial resources in the process of clinical trials, this study constructed an integrated intelligent management platform for clinical trials, which could carry out various types of clinical trials such as randomized controlled trials, non-randomized controlled trials, cohort studies, case-control studies, and cross-sectional studies simultaneously. The platform covers the whole process of scheme design, recruitment, follow-up, data analysis, and quality control. This paper mainly introduced the practical needs, design concept, basic framework and technical highlights to provide auxiliary tools for promoting the standardization and intelligence of clinical trials with energy saving and optimal efficiency.
ObjectivesTo analyze the development of acupuncture registered trials based on WHO international clinical trial registration platform (ICTRP) in the past 5 years.MethodsWHO ICTRP database was electronically searched to collect acupuncture-related clinical trials registered from January 1st, 2014 to December 31st, 2018. Two reviewers independently screened items, extracted data, and descriptive analysis was performed for the included trials.ResultsThe results showed that there were 1 556 registered clinical trials on acupuncture, and the most registered year was 2017. China was in the main country in applying for acupuncture-related clinical trials, however, the most registered unit was Kyung Hee University in Korea. The trials were mainly interventional research, mostly used randomized, blinded methods, and design modes were mainly based on parallel trials. In clinical trial phase, the majority were in the clinical trial period of treatment of new technologies. The field of clinical research was expected to be on pain in the future.ConclusionsAlthough acupuncture research is currently in a good stage of development, it should still value on the quality and innovative training of relevant trials, strengthen Chinese ties with other countries, focus on regional, domestic and international cooperation, expand research types, and enhance acupuncture applicability.