ObjectivesTo conduct a bibliometric analysis to research the status of disease burden domestically and overseas so as to understand the status of diseases burden, and to provide scientific and reasonable reference for health disease prevention, control strategies formulation and future research.MethodsPubMed, Web of Science, EMbase, The Cochrane Library, WanFang Data, CBM and CNKI databases were electronically searched to collect literature on disease burden from inception to October, 2018. Two reviewers independently screened literature and extracted data. EndNote X7 software was used for literature management, Excel 2016 software and VOS viewer software were also used to analyze data. Literature was classified by the aspects of literature publication characteristics, diseases, background areas, influencing factors, evaluation indicators and poverty caused by illness.ResultsA total of 325 studies were included in the bibliometric analysis. 41 articles (12.6%) were published in journals indexed by SCIE; original research evidence accounted for 97.0% (315 articles); 272 articles were from China (83.7%). The main diseases involved were malignant tumors (58 articles, 17.8%), diabetes (29 articles, 8.9%) and hypertension (24 articles, 7.4%). Factors affecting the disease burden primarily included hospitalization days (9 articles, 2.8%), complications (5 articles, 1.5%), delays in treatment (5 articles, 1.5%), and economic income (4 articles, 1.2%). Sixity-one articles (18.8%) reported poverty due to illness, and related diseases were chronic obstructive pulmonary disease (12 articles, 3.7%), hypertension (10 articles, 3.1%), diabetes (10 articles, 3.1%), malignant tumors (9 articles, 2.8%) and hepatitis B (6 articles, 1.8%).ConclusionsAt present, the disease burden research are focusing more on the burden of chronic non-communicable diseases such as malignant tumors, hypertension, diabetes, cardiovascular and cerebrovascular diseases in developing countries and regions. Medical costs vary from different diseases and treatment, different demographic characteristics of patients, and the coverage medical security of different population are the primary reasons for the " expensive in medical treatment” of current residents and the heavy burden of disease. DALY and total direct medical expenses are the main evaluation indexes of epidemiological burden and economic burden of disease, respectively. Future researches should focus on strengthening the scientific nature of study design to improve the quality of research, as well as paying more attention to diseases and aspects that are rarely involved, such as major diseases caused by poverty due to illness, comprehensive analysis of multiple diseases and aspects of health investment measurement, and comprehensively use the evaluation indicators of disease burden to strengthen the research on the comparability index of disease economic burden.
This is the fourth paper in the evidence-based medicine glossary series. Bibliometric method was used to analyse the development of evidence-based medicine in medicine and non-medicine system. Evidence-based medicine, Evidence-based nursing, Evidence-based practice, Evidence-based dentistry, Evidence-based emergency medicine have been defined in this paper.
ObjectiveTo gain an in-depth understanding of the research status, hotspots, and development trends in the field of ocular toxocariasis (OT). MethodsThe literature related to OT included in the Web of Science Core Collection dataset from 1993 to 2024 was retrieved and screened. The bibliometric softwares, VOSviewer and CiteSpace were applied to visually analyze the annual publication volume, countries, institutions, core authors, journal distribution, co-cited references, and keyword clustering. ResultsA total of 279 articles were included. There was an overall fluctuating upward trend of annual publications from 1993 to 2024, with the highest number of publications in 2020 (24 articles, accounting for 8.60%). There was an increasing trend in the frequency of citations to relevant literature. Authors from the United States had the highest number of publications (50 articles, 17.92%). Among institutions, Tokyo Medical and Dental University had the most the most published articles (11 articles, 3.94%). Among authors, professor Ding Xiaoyan from Zhongshan Eye Center at Sun Yat-sen University is the author with the most published papers (6 articles, 2.15%). Among journals, Ocul Immunol Inflamm had the highest number of published articles (21 articles, 7.53%). Highly cited references showed a significant clustering tendency, which were epidemiology, clinical characteristics and treatment, and immunological diagnosis. Keyword co-occurrence analysis showed that clinical features, serological diagnosis, epidemiology, immunodiagnosis, granuloma and treatment were high-frequency keywords. Timeline view map showed that the 9 clusters could be divided into 3 categories: epidemiological investigation including risk factors and seroprevalence (#0), clinical research including clinical features and treatment modalities (#1, #2, #3, # 6, #7), immunological detection and laboratory examination (#3, #5, #8). The keywords bursts analysis showed that the trend of research hot topics of OT had shifted from the initial study of animal experiments and immunological detection to the subsequent study of risk factor, and then to clinical characteristics studies combined with multimodal imaging technology. ConclusionsOver the past three decades, the number of publications on OT research has shown an increasing trend and the research hotspots have mainly focused on epidemiology, immunological detection and clinical features. The multimodal imaging diagnosis technology based on clinical features and the treatment strategy based on pathogenesis remain crucial directions for future research.
Objective To analyze and reveal the domestic and abroad studies on polypoidal choroidal vasculopathy (PCV) by bibliometric. Methods Foreign articles were searched from American Institute of Scientific Information online database of web of science (WOS) database, Chinese articles were searched from China National Knowledge Infrastructure (CNKI) database. The age distribution, national and regional, funding agency and citation of the PCV literatures published before December 31 2012 were analyzed by software Bibexcel and SPSS 17.0. Results Totally 696 literatures were analyzed, including 440 foreign literatures and 256 Chinese literatures. The numbers of foreign literatures were gradually increased since 2000, significantly after 2007, reached the maximum at 2011. The literatures were mainly in English, the number of the literatures of China ranked 4th of all countries. The National Natural Science Foundation of China ranked No.5 of funding agency. Citations gradually increased since 2000, increased significantly after 2008; there were 30 highfrequency subjects, and hot topics were clustered into 5 categories: treatment of PCV, genetics studies of PCV, detection, diagnosis and epidemiology of PCV, relationships between PCV and macular degeneration, related cytokine of PCV. Chinese literatures increased since 2000, significantly after 2006, and reached the maximum at 2010; there were 15 literatures supported by National Natural Science Foundation of China; Citation of Chinese literatures gradually increased since 2001, and reached the maximum at 2012. There were 30 highfrequency subjects, and hot topics were clustered into 5 categories: genetics and cytokine studies of PCV, detection and diagnosis of PCV, treatment of PCV, PCV and macular diseases, PCV and vitreous hemorrhage. Conclusions Literatures of PCV were gradually increased since 2000, abroad and domestic literatures of PCV reached maximum at 2011 and 2010 respectively. The abroad research of PCV focuses on 5 categories: treatment of PCV, genetics studies of PCV, detection, diagnosis and epidemiology of PCV, relationships between PCV and macular degeneration, related cytokine of PCV. The domestic research focuses on genetics and cytokine studies of PCV, detection and diagnosis of PCV, treatment of PCV, PCV and macular diseases, PCV and vitreous hemorrhage.
ObjectiveTo investigate the hotspots from researches on imaging of pancreatic neuroendocrine tumor in recent five years. MethodsThe bibliographies from research literatures on imaging of pancreatic neuroendocrine tumor from 2010 to 2015 in PubMed database were downloaded. The Bicomb 2.0 bibliographies analysis software was used to count high-frequency of Mesh major topics (MJMEs). SPSS 22.0 statistical software was applied for clustering analysis with MJMEs, then to get the topic hotspots. ResultsA total of 357 literatures were screened out during the years of 2010-2015. The MJMEs which frequency > 13 were 28. Taken the 28 MJMEs into clustering analysis, then three research hotspots were clustered. ConclusionResearches on imaging of the pancreatic neuroendocrine tumor in recent five years are mainly in terms of imaging techniques, a comparative study of pathology and endoscopic ultrasonography-fine needle aspiration, imaging and disease treatment.
ObjectiveTo explore the current situation, progress and hot spots of hospital-based health technology assessment (HB-HTA) at home and abroad. MethodsThe China National Knowledge Infrastructure (CNKI) and Web of Science databases were electronically searched to collect publications on HB-HTA. The bibliographic item co-occurrence mining system and VOSviewer software were used to extract and visually analyze HB-HTA literature. ResultsA total of 6 016 publications were included. Research on HB-HTA started late in China, however, it gradually increased in recent years. The Chinese research topics mainly focused on the application of hospital health technology evaluation in the management of medical equipment and consumables, and the English research topics mainly focused on the evaluation of the effectiveness, safety and cost of hospital health technology, especially information technology. ConclusionIn recent years, increasing attention has been given to HB-HTA. Related research topics have mainly focused on hospital technology access, management, and hospital health decision management.
Objective To learn the hotspots of study in ischemic optic neuropathy (ION). Methods Literature on ION published in January 2000 to July 2012 was identified in Pubmed database. MeSH terms that frequently appeared were identified and co-word analysis was carried out by cluster analysis. Then a network was drawn using social network analysis. Results A total of 1045 papers were included. The United States, England, Germany, France and Netherlands together accounted for 71.53% (748) of the articles. There were 28 high-frequency MeSH terms and hot topics clustered into four fields. The appearance frequency of MeSH showed that most research focused on: (1)postoperative or arteritic ION; (2)epidemiology, pathology and diagnosis of ION; (3)pathophysiology and therapy of ION; (4) chemically induced ION. Conclusion The international main research focus of ION includes four fields, which may provide reference or scholars both in scientific research and clinical research.
Objective To analyze the hot topics and trends of medical research integrity in China and to provide references for future studies. Methods The CNKI, WanFang Data and VIP databases were searched from inception to December 2021. Data on the number of publications, journals, institutions, authors, keywords, and emergent themes were analyzed using bibliometric methods and CiteSpace software. Results A total of 324 studies were included. The results showed that the number of publications increased annually, and "Chinese Journal of Medical Science Research Management" and Peking University were the journal and institution with the most publications, respectively. The three most prolific authors published five studies each, and the publications were mainly concerned with identifying and preventing issues, in addition to education regarding medical research integrity. Conclusion Medical research integrity in China has attracted significant attention. Several leading journals in this research field have emerged; however, there is no clearly dominant research team. The depth and breadth of the research remain to be improved. It is suggested that researchers focus on the effectiveness of strategies for preventing issues, promoting the establishment of the lifelong education system and improving related rules and regulations to advance the development of medical research integrity in China.
Objective To investigate how many hospitals can perform vitrectomy and its relationship to economic development in China.Methods Bibliometric data of retina-vitreous literatures were searched from the China National Knowledge Infrastructure (CNKI) academic databases. We used pars plana vitrectomy (PPV) as a keyword and defined address as mainland China, limited years to 1993 -2009. From those data we analyzed which hospital performed PPV. We also communicated with some hospitals by phone, email to confirm if they were performing PPV. Gross domestic product (GDP), population data and economic development ranking were extracted from the China Statistical Yearbook 2009 (National Bureau of Statistics of China). PPV carry-out rate, PPV-hospital shares and their relationships with the GDP in each regional municipality were analyzed.Results All together this study retrieved 4632 articles meet our requirements. There were 340 hospitals carrying out PPV in mainland China, located in 22 provinces, five autonomous regions and four metropolitan municipalities. The top five provinces with higher PPV carryout rate were Shandong (93,75%), Zhejiang (90,00%), Hebei province (90.00%), Jiangsu (83.33%) and Guangdong (75.00%). There was significant difference in per capita share of PPVhospitals between different cities (chi;2=181,153，P=0,000) and in the PPV carry-out rate between different cities (chi;2=749.217，P=0.000). There were 210 private eye hospitals in China,62 hospitals (18.23%) of them could perform PPV included 39 hospitals located in regionallevel cities. The coefficient correlation between PPV and GDP of different provinces was 0.842 (P=0.000). Conclusions Vitrectomy is widely performed in mainland China, but geographical distribution of PPV-performing hospitals is uneven. PPV performance is closely related with regional economic development,and private hospitals play certain roles in promoting the application of vitrectomy.
Objective To analyze the advancement and trends of English literature on elderly integrated care, and provide a reference for related research and practice in China. Methods Web of Science database was searched for English literature on elderly integrated care published between 1977 and 2000, and then CiteSpace software was applied to analyze and graphically present the articles to understand the chronological development, publishing institutions, research hotspots, key articles and so on. Results A total of 1177 English research papers on elderly integrated care were included. The yearly quantity of articles increased significantly since 2016. More than 100 articles had origin in the Unite State of America, the Netherland, the United Kingdom, and Canada, respectively; the organizations of those researches were mainly single programs, and the research fields were relatively scattered. The high-frequency keywords of these articles were health care, quality of life, primary care, home care, community, chronic disease, long term care, mental health, etc, and the burst terms were long term care, case management, quality of life, community, rehabilitation, telehealth, all inclusive care, etc. According to the centrality of co-citation clustering, the top one article was World Report on Ageing and Health published by the World Health Organization. Conclusions Elderly integrated care has been paid increasing international attention. In recent years, integrated care, transitional care, case management and telecare have become research hotspots. With the key policies of people-centred and integrated health services, primary care, and community-level interventions, typical countries have developed basic models of elderly integrated care. The above theories and experiences can provide references for the practice of elderly integrated care in China.