Lu-shan earthquake occurred at 8:02 am, on April 20th, 2013. The epicenter of earthquake was located in Lu-shan county, Ya’an city, Sichuan province, about 100 km from Chengdu along the Longmenshan fault zone in the same province heavily impacted by the 2008 Wenchuan earthquake. The earthquake has resulted in 196 people dead, 24 missing, at least 11,470 injured as of 14:30, April 24th, 2013. After Lu-shan earthquake, medical rescue teams were dispatched from the West China Hospital, Sichuan University to the stricken area. This article written by a member of the rescue team reported the difficult and dangerous rescue work and the performance of rescue members in the stricken area.
目的 探討適用于兒童的JumpSTART檢傷分類程序在大型車禍所致的含兒童群體傷中,對患兒受傷嚴重程度評估的實踐意義。 方法 回顧性分析2010年12月-2012年12月因大型車禍所致群體傷(3例以上傷員,至少含1例14歲以下兒童)就診的20例患兒的病歷資料。入急診時對患兒行JumpSTART檢傷分類程序,入院確診后行國際公認的能較準確反映傷情嚴重程度的損傷嚴重度評分(ISS)。比較兩種評估方法的一致性。 結果 JumpSTART檢傷分類程序與ISS評分一致性較好(Kappa=0.474,P=0.003)。 結論 JumpSTART檢傷分類程序可在含兒童的群體傷醫療急救時,初步評估患兒傷情嚴重度,從而進行檢傷分類。
ObjectiveTo systematically review the diagnostic value of procalcitonin (PCT) for tuberculous pleural effusion. MethodsWe electronically searched CNKI, WanFang Data, VIP, CBM, PubMed, The Cochrane Library and EMbase from inception to April, 2013, to collect the literature about the diagnostic value of PCT for tuberculous pleural effusion compared with gold standard (positive outcomes of mycobacterium tuberculosis culture). Two reviewers screened literature according to the inclusion and exclusion criteria, extracted data, and assessed the quality of included studies. MetaDiSc 1.4 were used to conduct the meta-analysis. ResultsEight studies were finally included. The results of meta-analysis showed the pooled sensitivity and specificity were 0.63 (95%CI 0.58 to 0.68) and 0.76 (95%CI 0.70 to 0.81), respectively. The positive likelihood ratio and negative likelihood ratio were 2.72 (95%CI 1.48 to 5.02) and 0.49 (95%CI 0.29 to 0.82), respectively. The diagnostic odds ratio (DOR) was 5.77 (95%CI 1.89 to 17.58). And the SROC AUC was 0.79. Heterogeneity was mainly derived from the QUADAS score and Begg's test showed there was no presence of publication bias. ConclusionPCT is a potential marker in the diagnosis of benign and tuberculous pleural effusion, which can be used to determine diagnosis identification of tuberculous pleural effusion.
目的 探討修正創傷評分(RTS)、CRAMS評分及院前傷情評分(PHI)對于群體傷患者死亡的評估作用。 方法 回顧性分析2011年8月-2012年8月就診且記錄完整的45例群體傷患者的病歷資料,根據病歷記錄計算RTS、CRAMS及PHI評分,并記錄患者是否死亡。繪制受試者工作特征曲線并計算出曲線下面積;根據約登指數篩選出各個評分適宜的截斷值,據此計算3種創傷評分的靈敏度、特異度、陽性似然比、陰性似然比、陽性預測值、陰性預測值并進行比較。將患者按照性別、年齡分為亞組進行對比分析。 結果 RTS曲線下面積最大,且與參考線下面積對比差異有統計學意義(P=0.016),與另外兩種評分比較其差異有統計學意義。 結論 RTS較CRAMS及PHI評分對于群體傷患者死亡預測具有更高的價值。
ObjectiveTo systematically review the diagnostic value of neuron specific enolase (NSE) for malignant pleural effusion. MethodsWe comprehensively searched databases including The Cochrane Library (Issue 1, 2012), EMbase, MEDLINE, CBM, CNKI, WanFang Data and VIP from inception to January 2012 to collect studies about the diagnostic value of NSE for malignant pleural effusion. Literature screening according to the inclusion and exclusion criteria, data extraction and methodological quality assessment were completed by two reviewers independently. Then Meta-DiSc software (version 1.4) was used for pooling analysis. ResultsA total of 12 studies were finally included. The results of meta-analysis showed that the value of pooled specificity, sensitivity, positive likelihood radio, negative likelihood radio and diagnostic odds ratio (DOR) were 0.79 (0.76 to 0.84), 0.55 (0.51 to 0.59), 3.2 (1.94 to 5.29), 0.58 (0.45 to 0.74), 7.56 (3.74 to 15.30), respectively; and the area under SROC curve (AUC) was 0.813 1. ConclusionUsing NSE as a maker to diagnose malignant pleural effusion is of certain clinical value, which is used to differentiate benign and malignant pleural effusion.
ObjectiveCurrently, simple triage and rapid transport (START) is widely used as a method to evaluate the severity of mass casualty events in a disaster. Modified physiological triage tool (MPTT) and modified physiological triage tool-24 (MPTT-24) are newly introduced triage methodologies that may offer improvements over START. However, the feasibility and accuracy of these two methods cannot be adequately assessed without sufficient data support, whether in earthquakes or other disasters. Our study aimed to analyze the value of the three triage methodologies in mass casualty events due to earthquakes.MethodsA total of 36 604 injured patients from the West China Hospital database were evaluated using START, MPTT and MPTT-24, respectively. The triage methodologies were then evaluated based on death and ICU acceptance, using the area under the receiver-operator curve (AUC). The sensitivity and specificity of the three methodologies were compared under different standards and correlations with the injury severity score (ISS) were analyzed. ResultsFor deaths, the AUCs for the triage methodologies were 0.711, 0.775 and 0.686 for START, MPTT, and MPTT-24, respectively. For ICU acceptance, the AUCs of the triage methodologies after correction for bias were 0.579, 0.618 and 0.603. The correlation coefficients of the triage methodologies and ISS score were 0.041, 0.087, and 0.115.ConclusionsMPTT is superior to START and MPTT-24 in the evaluation of critically ill patients in mass casualty events caused by earthquakes.
ObjectiveTo investigate the clinical value of quick sequential organ failure assessment (qSOFA) score in predicting the outcome of patients with septic shock. MethodsWe collected the clinical data of 170 patients with septic shock treated in the Emergency Intensive Care Unit between January 2013 and January 2014. According to the 28-day outcomes of the patients, they were recorded as survival group and non-survival group. We calculated the qSOFA score, acute physiology and chronic health evaluation (APACHE)Ⅱ score on patients' admission. Using receiver operating characteristic (ROC) curve, we analyzed the qSOFA score, the effect of APACHE Ⅱ score in predicting the 28-day prognosis for patients with septic shock. The correlation between qSOFA score and APACHEⅡ score was also assessed. ResultsThe qSOFA and APACHEⅡ scores in non-survivors were higher than those in the survivors. According to ROC curve analysis, the area under the curve for qSOFA score and APACHE Ⅱ score was 0.666 and 0.791, respectively. For qSOFA score with 2 cut-off points to evaluate the prognosis of septic shock, the sensitivity was 62.7%, specificity was 61.1%, positive predictive value was 56.0%, negative predictive value was 67.4%, positive likelihood ratio was 1.61, and negative likelihood ratio was 0.61. For the APACHEⅡ score with 24 cut-off points to evaluate the prognosis of septic shock, the sensitivity was 70.7%, specificity was 80%, positive predictive value was 73.6%, negative predictive value was 67.3%, positive likelihood ratio was 3.54, and negative likelihood ratio was 0.37. The correlation coefficient of qSOFA score and APACHE Ⅱ score was 0.499. ConclusionThe qSOFA score is useful to evaluate the prognosis of the patients with septic shock early in Emergency Department.
ObjectiveTo explore how to select the suitable indications of ERCP for clinical diagnosis and treatment. MethodsThe data of patients treated by ERCP between January 2005 and December 2009 in our hospital were analyzed retrospectively. ResultsTotal 221 patients received ERCP, among whom 99 (45%) cases of common bile duct stones, 44 (20%) cases of malignant tumor, 9 (4%) cases of papilla narrow, 45 (20%) cases were negative, and 24 (11%) cases were failed. It had the trend that the number of the patients received ERCP reduced year by year. The postoperative complication rate was 11% (25 cases), including 15 cases of postoperative pancreatitis, 3 cases of bleeding, 5 cases of biliary duct infection, and 2 cases of basket stranded. ConclusionIn the modern medical condition, with the advancement of image and laparoscopy technology, we should select the diagnosis and treatment methods with the principles of no damage or less damage for patients, without unlimitedly broadening the clinical indications of ERCP.
目的 探討H2受體拮抗劑和質子泵抑制劑(PPI)緩解急性胃黏膜損傷的時效性研究。 方法 對2008年1月-2010年1月在急診科就診的98例急性乙醇中毒后胃黏膜損傷患者,隨機分為對照組50例,治療組48例。常規給予休息、保暖,補液,維持水、電解質、酸堿平衡,維持循環功能等治療基礎上,對照組給予H2受體拮抗劑治療,治療組給予PPI治療。通過觀察急性胃黏膜損傷患者上消化道癥狀及體征,記錄不同飲酒及飲酒量,并根據患者就診時間及不同飲酒組治療后上消化道癥狀完全緩解時間進行比較。 結果 治療組上消化道癥狀緩解所需時間與對照組比較差異有統計學意義(P<0.001),不同飲酒組上消化道癥狀緩解時間上差異有統計學意義(P=0.000)。 結論 PPI在緩解急性乙醇中毒所致胃黏膜損傷的時效上更明顯,具有臨床價值。
ObjectiveTo study whether emotional management can alleviate the occupational burnout of the health care providers. MethodsFrom May 1st 2015 to February 29th 2016, we sampled the medical workers of a class-3 grade-A hospital randomly, and performed the emotional management through self-emotion management and professionals-conducted emotion-management. The discrepancies before and after intervention were studied using Maslach Burnout Inventory General Survey (MBI-GS). ResultsIn total, 100 medical workers were enrolled in our study, of which there were 27 males and 73 females. There were 11 doctors and 89 nurses. The average age was (34.5±5.6) years. According to the MBI-GS survey, there were 69 medical workers suffering from occupational burnout. There were significant statistical differences before and after intervention in the MBI-GS scores in four aspects including emotion exhaustion, work status, sense of achievement and the total scores (P<0.05). ConclusionThe medical workers can alleviate the occupational burnout under the self-management or professionals-conducted management of emotion.