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      2. west china medical publishers
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        find Author "王娟" 33 results
        • 自身免疫性肝炎/原發性膽汁性肝硬化重疊綜合征誤診為藥物性肝炎一例

          【摘要】 目的 提高對自身免疫性肝病的認識。 方法 報道一例自身免疫性肝炎/原發性膽汁性肝硬化重疊綜合征誤診為藥物性肝炎,并綜述相關文獻總結其臨床表現、診斷、治療及預后。 結果 自身免疫性肝病是一組以肝臟病理損害和肝功能異常為主要表現的自身免疫性疾病,可分為自身免疫性肝炎(autoinmmune hepatitis,AIH)和(primary biliary cirrhosis,PBC)及原發性硬化性膽管炎(primary sclerosing cholangitis,PSC)。由于無特異性的臨床表現,容易漏診或誤診為藥物性肝炎,診斷主要依靠生化及免疫學檢查。AIH/PBC重疊綜合征的治療目前無成熟經驗,主要藥物包括熊去氧膽酸(UDCA)、糖皮質激素和免疫抑制劑等。 結論 對于不明原因的肝損害患者應做免疫學篩查。

          Release date:2016-09-08 09:52 Export PDF Favorites Scan
        • A BIOMECHANICAL STUDY ON CORACOACROMIAL LIGAMENT AS ANTEROSUPERIOR RESTRAINT OFSHOULDER JOINT

          Objective To determine the change in humeral head anterosuperior migration after releasing the coracoacromial l igament in shoulders from cadavers with simulated intact or irreparable teared rotator cuff, to provide biomechanical basis for preserving the coracoacromial l igament or not during hemiarthroplasty. Methods Twelve freshfrozen cadaveric glenohumeral joints of adult preserving the scapula, upper 2/3 of the humerus, articular capsule and the coracoacromial l igament, were divided into 2 groups. The suprascapularis was preserved in group A (6 shoulders) and excised in group B (6 shoulders). Positioning the joint in a combination of 30° extension, 0° abduction and 30° external rotation, and imposing a 50 N axial compressive load to the humeral shaft, the anterosuperior displacement of the humeral head weremeasured before and after excising the coracoacromial l igament. Results In group A, the displacement of the humeral head was (5.96 ± 0.77)mm with intact coracoacromial l igament and (6.83 ± 0.84)mm after transecting the l igament. In group B, the displacement of the humeral head was (8.07 ± 2.46)mm with intact coracoacromial l igament and (9.92 ± 3.29)mm after transecting the coracoacromial l igament. So the mean increase of anterosuperior migration of the humeral head was (0.88 ± 0.34) mm (P lt; 0.01) in group A, and (1.85 ± 0.99) mm (P lt; 0.01) in group B, which was greater than the former (P lt; 0.05). Conclusion The coracoacromial l igament restrained anterosuperior translation of the humeral head, especially for patients with rotator cuff deficiency, so it should be preserved as far as possible during hemiarthroplasty.

          Release date:2016-09-01 09:05 Export PDF Favorites Scan
        • Efficacy of Wechat combined with continuing nursing on ketogenic diet children, parents and medical staff

          Objective To evaluate the efficacy of Wechat combined with continuing nursing on the quality of life of epilepsy children with ketogenic diet, parents' mood and the time commitment of medical staff. MethodsData were collected from 140 children with intractable epilepsy with ketogenic diet admitted to the Department of Neurology, Children's Hospital Affiliated to Chongqing Medical University from November 2014 to June 2022, including 116 males and 24 females, with an average age of (8.42±2.44) years. The random sampling method was divided into control group (continuing nursing) 71 cases, intervention group (Wechat combined with continuing nursing) 69 cases. The quality of life of the children (QOLCE-16) in the two groups was compared before discharge and 3 months after discharge, as well as parental anxiety (SAS), depression (SDS), and the amount of time medical staff spent with both groups. ResultsThere was no difference in the quality of life and parental emotion between the two groups before intervention. After 3 months, the quality of life of the two groups was significantly improved [(43.59±10.00) vs. (40.14±10.44), P<0.05], and the QOLCE-16 score of the intervention group was higher than that of the control group (P<0.05). The parental mood SAS and SDS in both groups were significantly improved [(37.19±2.90) vs. (50.85±3.76), (40.14±3.52) vs. (49.29±3.37), P<0.01], and the SAS and SDS scores of anxiety and depression of parents in the intervention group were lower than that of the control group (P<0.01). Medical staff spent more time on intervention group [(136.17±7.43) vs. (65.55±7.48), P<0.01]. ConclusionContinuing nursing can improve the quality of life of children with ketogenic diet and the negative emotions of their parents. The combination of Wechat and continuing nursing can further strengthen this positive effect, and requires more time of medical staff.

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        • 重組人白細胞介素11在白血病患者化學治療后口腔潰瘍的療效觀察

          目的 針對白血病患者化學治療(化療)后口腔潰瘍及疼痛問題,探討其治療及護理措施。 方法 2010年10月-2012年2月,將98例白血病化療后發生口腔潰瘍患者分為觀察組、對照組各49例,觀察組使用重組人白細胞介素11(rhIL-11)配置為漱口液治療,對照組使用重組人粒細胞刺激因子注射液(GM-CSF)配置為漱口液治療。 結果 治療3 d后,觀察組患者口腔黏膜反應分度情況明顯好于對照組,觀察組患者口腔潰瘍愈合時間較對照組好。 結論 使用rhIL-11可有效治療白血病患者化療后口腔潰瘍的發展與愈合,有利于化療計劃的順利完成。

          Release date:2016-09-08 09:14 Export PDF Favorites Scan
        • 誤診為肺結核的先天性左主支氣管食管瘺一例

          臨床資料 患者男性, 62 歲。因“反復咳嗽、咯痰2 年, 加重伴氣喘20 d”入院。2 年前患者每遇受涼后出現咳嗽, 呈陣發性, 以夜間為主, 右側臥位較左側顯著, 咯少量白色黏痰, 易咳出。無痰中帶血,無胸痛, 無明顯氣喘、氣短, 無心慌、胸悶, 無吃流質食物及飲水時嗆咳。經常覺腹脹, 打Atilde;后可稍減輕,按氣管炎抗感染治療后癥狀減輕。近2 年來, 因癥狀反復發作, 曾在多家醫院診斷為肺結核而行標準四聯抗結核治療, 但癥狀緩解不明顯。20 d 前患者受涼后咳嗽加劇, 呈陣發性刺激性咳嗽, 咯白色黏痰, 每次3 ~5 mL, 每日10 余次, 無痰中帶血, 無胸痛, 無心慌、胸悶, 無聲音嘶啞, 無盜汗, 自覺乏困無力, 腹脹較前加劇, 活動后感氣短、氣喘, 精神差。在當地診所靜滴“頭孢唑啉( 5. 0 g/ d) ”治療6 d 后咳嗽、咯痰減輕, 氣喘、氣短無明顯變化, 遂來我院以“急性支氣管炎”收住。本次發病以來無發冷、發熱; 無盜汗; 無頭昏、頭痛; 無惡心、嘔吐; 無腹痛、腹瀉; 食納、夜休差, 二便正常。既往體健。......

          Release date:2016-09-13 03:50 Export PDF Favorites Scan
        • Emergent Financial Management in West China Hospital during Medical Rescue after Wenchuan Earthquake

          The Department of Finance, West China Hospital, Sichuan University, Chengdu 610041, ChinaAbstract?During the medical rescue of the earthquake, the Department of Finance of West China Hospital initiated emergency response plan, not only ensured the security of funds of hospital in the earthquake, but also opened a green channel of emergent finance to the wounded, so as to assure more than 2?600 wounded people of their registration for emergency treatment, emergent disposal, hospitalization, operation and medication, the comprehensive, precise and prompt record of which offered the government the basic data and references to work out the policy of financial subsidy for the treatment of the wounded. Furthermore, the financial supervision and management of materials and funds of disaster relief were reinforced.

          Release date:2016-09-07 02:12 Export PDF Favorites Scan
        • Ultrasonography in the Diagnosis of Benign and Malignant Breast Masses

          目的:探討乳腺良惡性腫塊二維超聲圖像和彩色多普勒血流狀況,提高乳腺腫塊的超聲診斷符合率。方法:回顧性分析105例乳腺腫塊的二維及彩色多普勒超聲圖像特點。結果:本組惡性腫塊37例,超聲診斷和疑診惡性腫塊32例,符合率為865%(32/37);良性腫塊68例,超聲診斷良性腫塊58例,符合率為853%(58/68)。乳腺良惡性腫塊在形態、 邊界、 包膜、 內部回聲、 后方回聲、 沙粒樣鈣化、血流形態分布,血流動力學等方面具有明顯差異。結論:二維及彩色多普勒超聲對良惡性乳腺腫塊有較高鑒別診斷價值。

          Release date:2016-08-26 02:21 Export PDF Favorites Scan
        • ABO血型不合干細胞移植患者急性血管內溶血反應的護理一例

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        • Assessment of Liver Perfusion in Hepatitis Pregnant Women by Three-dimensinal-sonography Power Doppler Vascular Indexes

          ObjectiveTo evaluate liver perfusion in pregnant women with hepatitis between 13 and 41 weeks of gestation by three-dimensional color power Doppler angiography (3D-CPA) vascular indexes. MethodsThis study involved 73 pregnant women with hepatitis and 44 healthy pregnant women who had the pregnancy examination between February 2012 and June 2013. We sampled in the area which was near the right lobe of the pregnant women liver's portal vein branch, and obtained the vascularization index (VI), flow index (FI) and vascularization flow index (VFI) via the virtual organ computer-aided analysis (VOCAL) method. Then, we compared the liver perfusion differences between the pregnant women with hepatitis and healthy pregnant women. ResultsThe hepatic flow indexes obtained by 3D-CPA were significantly different between the HBV-DNA viral load and the control groups. The cutoff values of the three vascular indexes of patients with hepatitis with HBV-DNA viral load and the healthy pregnant women were respectively VI=8.760 (P<3×10-4); FI=22.180 (P<6×10-7); and VFI=1.575 (P<3×10-5). ConclusionApplication of the 3D-CPA on liver perfusion may differentiate pregnant women with hepatitis B from normal ones, thus offer a support for clinical prevention and treatment for pregnant women with hepatitis B.

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        • Maxillofacial Osseous Reconstruction in One-stage Operation Combined with Craniotomy for Moderate Craniocerebral Injury

          ObjectiveTo explore the value of maxillofacial osseous reconstruction in one-stage operation combined with craniotomy for moderate craniocerebral injury. MethodsA retrospective study was conducted by analyzing the clinical and radiographic results of 13 patients treated between January 2008 and February 2015. Among them, 7 patients admitted into the hospital between January 2008 and December 2009 were regarded as the control group. Among the 7 patients, 5 were males and 2 were females, aged between 22 and 66 years old, averaging (44.3±15.9) years old. The patients of the control group underwent craniotomy within 24 hours after admission, and accepted the second stage operation for maxillofacial reconstruction 3 to 5 weeks later. The other 6 patients including 4 males and 2 females aged between 27 and 57 years old, averaging (40.2±10.7) years old, admitted into the hospital between January 2010 and February 2015 were designated into the observation group. They underwent maxillofacial osseous reconstruction in one-stage operation combined with craniotomy within 24 hours after admission. The treatment effect, leakage of cerebrospinal fluid, intracranial infection and average length of stay were analyzed and compared. ResultsIn the control group, there were 5 cases of cerebrospinal rhinorrhea preoperatively, and all were cured after craniotomy. During the second stage operation for maxillofacial reconstruction, bone callus and scar tissue presented in all cases and poor reconstruction occurred to 3 cases. After reconstruction, cerebrospinal rhinorrhea recurred in 2 cases. The average length of stay was (43.4±4.5) days. For the observation group there were 3 cases of cerebrospinal rhinorrhea preoperatively, and one of them remained after the operation and cured 7 days later. The average length of stay was (22.7±2.7) days. None of the 13 patients suffered intracranial infection. ConclusionMaxillofacial osseous reconstruction should be considered in one-stage operation combined with craniotomy for moderate craniocerebral injury

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          2. 射丝袜