Objective To explore the correlation between metabolic syndrome and renal function in physical examination population. Methods The data of individual physical examination in West China Hospital from March to April 2015 was collected. Body mass index (BMI), glomerular filtration rate (GFR) were calculated, and the correlation between metabolic syndrome and renal function was analyzed by using SPSS 16.0 software. Results A total of 10?098 individuals were included, of which 1?110 were MS patients were included. The results of analysis showed that, the levels of uric acid, cholesterol, urea and creatinine in MS group were significantly higher than those in non-MS group, and the level of GFR was significantly lower than that in non-MS group (P < 0.05). Renal function in patients with abnormal systolic blood pressure, diastolic blood pressure, fasting blood glucose (FBG), low density lipoprotein, total cholesterol, triglycerides, uric acid index were significantly higher than those in normal renal function group, and high density lipoprotein cholesterol was significantly lower than that of normal renal function group (P < 0.01). Conclusion Elevated levels of BMI, blood pressure, glucose, uric acid are correlated with the decrease of GFR, and metabolic syndrome is an important risk factor of renal dysfunction.
目的 探討成都地區高尿酸血癥發生的危險因素。 方法 收集2009年10月－2010年4月在四川大學華西醫院體檢中心進行健康體檢的36 639人的臨床資料，對資料進行單因素分析和多因素logistic回歸分析。 結果 進行健康體檢的36 639人，其中男21 175人，女15 464人。高尿酸血癥患者5 233例，患病率為14.3%。年齡＞50歲、男性、飲酒、糖尿病、高血壓病、甘油三酯增高、低密度脂蛋白增高和血清肌酐水平增高與高尿酸血癥的發生有關。Logistic回歸分析顯示男性（OR=13.300，P=0.000）、飲酒（OR=4.219，P=0.009）、糖尿病（OR=3.609，P=0.024）是發生高尿酸血癥獨立危險因素。 結論 成都地區高尿酸血癥的患病率略高于全國平均水平，臨床治療和護理高尿酸血癥的患者時應積極控制與高尿酸血癥發生密切相關的危險因素。
Objective To review literatures regarding the diagnosis of asthma with the measurement of exhaled nitric oxide( eNO) and assess the effectiveness and accuracy of eNO in the diagnosis of asthma.Methods MEDLINE, OVID, CBMdisc, CNKI( 1991 to 2008) for studies involving the diagnostic value of eNO were searched, and references of included studies were also hand searched. QUADAS ( Quality Assessment of Diagnostic Accuracy Studies) items were used for quality assessment in the systematic review. Meta-disc software was used to analyze heterogeneity. Sensitivity, specificity and summary diagnostic odds ratio( SDOR) were used for the pooled analysis. The summary receiver operating characteristic ( SROC)curves were drew and the summary areas under the SROC ( SAUC) were calculated. Finally, sensitivity analysis was performed. Results Eleven literatures with15 studies were included. These 15 studies had well controlled the bias of partial verification, differential verification, incorporation and withdrawals. The possibility of the disease progression bias was less and the reference standard review could have a greater bias. The spectrumcomposition of a study, the inclusion and exclusion criteria and the reporting quality were poorly reported. In statistical analysis, the totally pooled sensitivity, pooled specificity, SDOR, SAUC of the measurement of eNO in the diagnosis of asthma was 0. 68, 0. 79, 12. 73, 0. 8446, respectively. Sensitivity analysis demonstrated no disproportionate influences of individual study. Conclusions eNO has a certain value in the diagnosis of asthma. To make further analysis, more studies with high quality are needed.
ObjectiveTo investigate the relationship between nonalcoholic fatty liver disease (NAFLD) and Helicobacter pylori (HP) infection. MethodsMedical examination data of healthy physical examination participates who underwent carbon 14 urea breath test for detection of HP and abdominal ultrasound examination between March and June 2015 were analyzed. Cross sectional analysis was carried out. Based on the diagnostic criteria of NAFLD, the subjects were divided into two groups: NAFLD group and normal control group. HP infection was compared between the two groups. Logistics regression analysis was performed to analyze the relationship between HP infection and NAFLD. ResultsThe proportion of men, age, weight, body mass index (BMI), waistline, alanine aminotransferase (ALT), aspartate aminotransferase, glutamyl transferase, albumin, fasting blood-glucose (GLU), total cholesterol triacylglycerol (TG), low density lipoprotein-cholesterol, and blood pressure were all significantly higher in the NAFLD group than the control group (P < 0.05), while height and high density lipoprotein-cholesterol were significantly lower in the NAFLD group (P < 0.05). The detection rate of NAFLD in males was higher than that in females. The detection rates of NAFLD in different age groups were significantly different, and the highest detection rate of NAFLD was in the age group of 50-59 years old (P < 0.05). The rate of HP infection was not significantly different in subjects of different ages and genders (P > 0.05). The rate of HP infection in the NAFLD group was significantly higher than those of the control group in age groups of 18-29, 30-39, 40-49, 50-59, and 70-79 years old (P < 0.05). The logistic regression analysis revealed that age, HP infection, TG, ALT, BMI, GLU, and diastolic pressure were correlated with NAFLD (P < 0.05). ConclusionHP infection may be a risk factor in the development of NAFLD.
ObjectiveTo explore the prevalence rate of gynecologic diseases and its character of age distribution of women in Chengdu, China. MethodsWe retrospectively analyzed gynecologic examination reports of women who underwent physical examination from December 2011 to November 2012. ResultsThis study included 23 389 women; the overall detection rate of cervix erosion was 20.98%. The detection rate of cervix erosion of women aged from 20 (included) to 30 was 44.81%, ranking first. The overall rate of abnormal cervical cytology was 0.93%, and the rate of women aged 41 to 50 was 1.20%, ranking first. The overall detection rate of uterine myoma, uterine adenomyosis, and ovarian tumor was 11.12%, 1.33%, and 3.60%, respectively. Fourty-one to 50 was the peak age of uterine myoma, uterine adenomyosis, and ovarian tumor; the detection rate was 19.95%, 2.46%, and 4.76%, respectively. The difference was significant in different age (P<0.05). ConclusionThe detection rate of gynecological common disease is high in childbearing aged women. Women aged 41-50 is the high-risk population of gynecological common disease.
ObjectiveTo investigate the checkup residents' requirements for the health management and its influence factors. MethodsThe data from 741 checkup clients were randomly sampled by questionnaire in checkup center in May, 2013, including 360 males and 381 females aged from 24 to 69 with an average of 43.5±11.2. ResultsThere were 668 valid questionnaires, with an effective rate of 90.1%. In these 326 males and 342 females, 589 (88.2%) had the consciousness of health management, 79 (11.8%) had no consciousness of health management; the health management services needs included:consultation offered by experts of examination report (556, 83.2%), health promotion plan (379, 56.7%), medical follow-up (301, 45.1%), green channel (280, 41.9%), health knowledge message (276, 41.3%) and lecture on health knowledge (200, 29.9%). The demand for health management differed in sex, age and checkup format(P<0.05), not in chronic disease conditions (P>0.05); the requirement for lecture differed in age and occupation(P<0.05); the requirement for health promotion plan differed in economic condition(P<0.05); the requirement for message and green channel differed in age and checkup pattern(P<0.05). ConclusionThe checkup residents' have high requirements for the health management and differ in health management services.