ObjectiveTo investigate the effectiveness of the tubal reconstruction after laparoscopic tubal pregnancy operation by comparing with simple laparoscopic tubal pregnancy operation. MethodsBetween May 2007 and May 2010, 63 patients with tubal pregnancy underwent laparoscopic tubal pregnancy operation and tubal reconstruction in 30 cases (trial group) or simple laparoscopic tubal pregnancy operation in 33 cases (control group). There was no significant difference in age, pregnancy time, and position between 2 groups (P gt; 0.05). The tube patency test and hysterosalpingography (HSG) were carried out to evaluate the efficacy. ResultsThe operation was successfully completed in 29 cases of trial group; 1 case had too severe adhesion to receive re-anastomosis and was excluded. The tube patency test showed that the tube was patency in 26 cases of trial group and in 2 cases of control group during operation, showing significant difference (Z=5.86, P=0.00); it was patency in 25 cases of trial group and in 26 cases of control group at 1 month after operation, showing no significant difference (Z=0.48, P=0.63). HSG examination showed tube was patency in 25 cases of trial group and in 2 cases of control group at 2 months after operation, showing significant difference (Z=5.35, P=0.00). After 24 months, intrauterine pregnancy of trial group (n=25, 86.20%) was significantly higher than that of control group (n=19, 57.58%) (χ2=7.72, P=0.01). ConclusionThe reconstruction after laparoscopic tubal pregnancy operation can significantly increase the intrauterine pregnancy rate, and it is better than simple laparoscopic tubal pregnancy operation.
觀察受體鼠妊娠和胚胎著床情況,并檢測胚胎移植時小鼠子宮內膜中白血病抑制因子(Lif)表達水平,探討超排卵對小鼠胚胎著床潛能的影響。方法:建立超排周期胚胎和自然周期胚胎移植小鼠模型,比較妊娠率、胚胎著床率的差異及其與Lif蛋白的表達水平之間的關系。結果:超排卵周期受體組的妊娠率(20.00%)和胚胎著床率(8.33%)顯著低于自然周期組的妊娠率(55.00%)和胚胎著床率(35.00%)(P＜0.05)。自然周期胚胎和超排周期胚胎受體組內膜中Lif蛋白的表達水平相似(P＞0.05),妊娠受體組Lif蛋白的表達水平顯著高于未孕受體組(P＜0.05),但單胎妊娠和多胎妊娠受體組內膜中Lif蛋白的表達水平相似(P＞0.05)。結論:超排卵可能降低胚胎的著床潛能,Lif蛋白的表達水平與胚胎著床有關,但與著床胚胎的數目無比例關系。
Objective To systematically review the association between periodontal disease during pregnancy and the risk of gestational diabetes mellitus (GDM). Methods PubMed, Web of Science, CBM and CNKI databases were electronically searched to collect studies on periodontal disease and GDM from inception to October 23, 2021. Two researchers independently screened literature, extracted data and assessed the risk of bias of the included studies. Meta-analysis was then performed using RevMan 5.4 software. Results A total of 11 studies were included, involving 2 910 pregnant women. The results of meta-analysis showed that pregnant women with periodontal disease during pregnancy reported more GDM than normal pregnant women (OR=1.81, 95%CI 1.31 to 2.50, P=0.000 3). Conclusion The current evidence suggests that there is a positive association between periodontal disease during pregnancy and the risk of GDM. Due to the limited quantity and quality of the included studies, more high-quality studies are needed to verify the above conclusion.
ObjectiveTo investigate the effect of behavior intervention through diets and exercises on blood glucose controlling in patients with gestational diabetes mellitus (GDM), and to provide the basis for GDM therapy. MethodsA total of 116 patients with GDM diagnosed and treated in the Sixth Affiliated Hospital of Sun Yat-sen University between March 2011 and December 2012 were taken as our study objects, including 72 patients in the study group and 44 patients in the control group, based on their will. For patients in the study group, we carried out behavior interventions through diets and exercises, including dietary guidance, giving pamphlet and formulating exercise plan, while for patients in the control group, we only gave them oral guidance and publicity materials. The same questionnaire was used to collect all the patients' information. Follow-up was done once in every 3 days, and rechecking was performed 2 weeks later. The results of oral glucose tolerance test and the rate of pathoglycemia were compared in these groups before and after intervention. ResultsThe fasting blood glucose, 1- and 2-hour blood glucose were lowered after the behavior intervention in the study group (P<0.05), which were also significantly lower than the control group (P<0.05). Fasting blood glucose, 1- and 2-hour pathoglycemia was significantly lower in the study group than that in the control group and that before intervention (P<0.05). ConclusionCombination of diets and exercises can control levels of blood glucose in GDM patients, and is an important therapy for GDM.
【摘要】目的探討瘢痕子宮不全破裂的早期診斷、處理及預防。方法2006年1月2009年1月發生瘢痕子宮不全破裂13例,術前臨床癥狀加B超檢查確診,手術從原切口進入宮腔,取出胎兒,修剪原切口周圍瘢痕組織,10可吸收線連續縫合漿肌層,再間斷包埋縫合切口,術后常規預防感染,加強宮縮治療;胎盤植入2例盡量取出胎盤,修整切口,活動性出血明顯者用10可吸收線“8”字縫扎止血,術后加服米非司酮150 mg/d共3 d。結果母嬰均痊愈出院。42 d后來院復查,B超探查8例子宮下段處有線狀較強回聲,肌層回聲均勻,余未發現異常;胎盤植入2例，隨防3個月血絨毛膜促性腺激素呈陰性。結論早期B超檢查能提高瘢痕子宮不全破裂確診率,確診后急診剖宮產,胎盤部分植入者加服米非司酮并預防感染。