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達芬奇機器人甲狀腺手術中甲狀旁腺保護策略與技巧

Value of Internal Mammary Lymph Node in Staging and Adjuvant Therapy of Breast Cancer

ObjectiveTo analyze the value of internal mammary lymph node biopsy via intercostal space in staging and adjuvant therapy of breast cancer. MethodsThe clinical data of 305 breast cancer patients received any kind of radical mastectomy from may 2003 to January 2014 in the Jinan Military General Hospital of PLA were analyzed retrospectively. The patient age, axillary lymph node, and internal mammary lymph node status were integrated to investigate the changing of staging and postoperative adjuvant therapy of the breast cancer. ResultsThese 305 patients were divided into neoadjuvant chemotherapy group and non-neoadjuvant therapy group. There were 67 patients in the neoadjuvant chemotherapy group, including 45(67.2%) patients with axillary lymph node positive, 23(34.3%) patients with internal mammary lymph node positive. There were 23(34.3%) patients who had a change of pathology lympy node (pN) staging and 8(11.9%) patients who had a change of the pTNM staging. Meanwhile, there were 238 patients in the non-neoadjuvant chemotherapy group, including 155(65.1%) patients with axillary lymph node positive, 30(12.6%) patients with internal mammary node positive. There were 30(12.6%) patients who had a change of the pN staging and 23(9.66%) patients who had a change of the pTNM staging. There was a significant difference in the metastasis rate of the internal mammary lymph node (χ2=15.7, P < 0.05) or the changing ratio of the pTNM staging (χ2=5.3, P < 0.05) in two groups. ConclusionsInternal mammary lymph node status could affect pN staging of breast cancer, so do the pTNM staging (TNM, pathology tumor, lymph node, metastasis). The internal mammary lymph node status could guide the postoperative adjuvant radiative therapy by reducing excessive treatment of the internal mammary lymph node area, also could enhance the individual accurate therapy.

動脈栓塞聯合手術治療復雜化生性乳腺癌1例報道

甲狀腺癌頸淋巴結清掃術后難治性乳糜漏臨床分析

目的 分析甲狀腺癌手術后難治性乳糜漏的臨床特點，探討難治性乳糜漏的治療策略。方法 回顧性分析解放軍第九六〇醫院（原濟南軍區總醫院）2009年 1 月至 2021 年1 月期間收治的 5 021例行甲狀腺癌頸淋巴結清掃術患者的臨床資料，術后發生乳糜漏122例，其中治療時間超過2周的難治性乳糜漏34例，對難治性乳糜漏患者的一般情況、治療方式、峰值引流量（日最高引流量）、帶管時間等進行分析總結。結果 5 021例患者中發生乳糜漏122例，占所有患者的2.4%。經非手術治療2周內治愈者88例，占乳糜漏總數的72.1%；治療時間超過2周的難治性乳糜漏34例，占乳糜漏總數的27.9%。難治性乳糜漏經非手術方法治愈者18例，經再次手術治愈者16例，2組患者的乳糜漏位置左側多于右側；34例難治性乳糜漏峰值引流量（日最高引流量）手術組（16例）高于非手術組（P<0.05），帶管時間手術組短于非手術組（P<0.05）。結論 低峰值引流量乳糜漏經非手術治療多可治愈；難治性乳糜漏左側多見，高流量乳糜漏（峰值引流量≥1 000 mL）宜早期實施手術治療。