In 2024, the European Confederation of Medical Mycology, the International Society for Human and Animal Mycology, and the American Society for Microbiology jointly published the first global clinical guideline for cryptococcosis in The Lancet Infectious Diseases, which systematically established differentiated diagnostic and treatment strategies tailored to distinct host types and infection sites. This article provides an in-depth interpretation of the guideline, focusing on critical clinical aspects including diagnosis and screening of cryptococcal infection, management of central nervous system (CNS) infections, pulmonary infections, non-CNS/non-pulmonary infections, intervention strategies for complications such as immune reconstitution syndrome, and individualized treatment recommendations for special populations (pregnant women and children). The article aims to deliver standardized and actionable clinical guidance for healthcare providers, facilitating optimized comprehensive management of cryptococcosis across multi-tier healthcare institutions.
目的 通過應用數據包絡分析（DEA）方法對醫院科室運營效率進行評價，分析DEA方法在醫院臨床科室相對效率評價中的價值。 方法 采用聚類分析等確定投入產出指標，采用DEA方法中C2R和BC2模型對2004年1月－2008年12月各科室相對效率進行評價和分析。 結果 70個被評價單元中有41個被評價單元的總體有效值為1，屬于相對有效單元；29個被評價單元的C2R模型總體有效值＜1，屬于相對無效單元。 結論 DEA方法適用臨床科室相對效率評價多投入、多產出的特點，能夠有效識別被評價單位中的無效單元，并且對于投入產出值能夠指明導致無效的方向和需調整的程度，指導相關管理部門對科室的調整和資源投入方向。
Co-infection with severe influenza and bacterial is well known, but in recent years, more and more studies report that aspergillus have been identified as important pathogens, secondary only to bacteria in severe influenza. Influenza-associated aspergillus (IAA) brings a high death rate and heavy burden to our country. Therefore, early diagnosis and effective treatment are needed. In order to better understand IAA, this review summarizes the available literature on the association of IAA, including epidemiology, diagnosis and treatment.
This paper compares emergency medical rescue experience of West China Hospital of Sichuan University in the latest three earthquakes occurred in western Sichuan, and mainly introduces the experience in organization and coordination, rescue speed, treatment of the injured, and rescue characteristics in Jiuzhaigou earthquake, which can provide reference for future earthquake emergency medical rescue.
Objective To discuss the clinical value of whole spine magnetic resonance imaging (WSMRI) in practice of neurosurgical spinal surgery. Method A total of 70 cases examined using WSMRI between January 2015 and December 2016 were collected and analyzed retrospectively. Results All patients got clear images of WSMRI. Eighteen cases got important information, including spinal variation (1 case), multiple lesions (3 cases), combined lesions (6 cases) and large range multi-segmental lesions (8 cases), which were missed by single-segment MRI . Conclusions WSMRI can show all the spine, spinal cord and surrounding tissue in one image at one time. It has high clinical value because of its accurate positioning, comprehensiveness, time saving, and low rate of misdiagnosis and missed diagnosis.