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      2. west china medical publishers
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        find Keyword "Science" 27 results
        • Bibliometrics on Electronic Health Records of Web of Science

          Objective To investigate the current status and development of electronic health records (EHR) at home and abroad to grasp the development trends of EHR, so as to point out the direction of the development and relevant research on EHR. Methods Based on the Web of Science citation database and the principle of bibliometrics, we analyzed the retrieved literature in aspects of publication date, language, country/region, institution, author, etc. Results A total of 1 262 eligible studies were identified. The number of articles on EHR increased rapidly from only 2 in 1995 to 218 in 2012. In terms of country/region, the United States ranked the top in all countries (763 articles, accounting for 60.46%). In terms of institution, Harvard University ranked the top (135 articles, accounting for 10.70%). In terms of journal, the Journal of the American Medical Informatics Association ranked the top (106 articles, accounting for 8.40%). In terms of authors, David W. Bates ranked the top (45 articles, accounting for 3.57%). In terms of subject type, health care sciences services and medical informatics were mainly focused on. Conclusion The research on EHR has become a global hot spot and relevant bibliometrics will contribute to the timely and correctly grasp the whole picture of its development trends and main research direction.

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        • Bibliometric Analysis of Sleep Apnea Syndrome Based on Science Citation Index

          Objective To reveal the worldwide research status and hot topics of sleep apnea syndrome ( SAS) . Methods Articles were searched from Web of Science ( SCI) , Essential Science Indicator ( 2000 to 2010) database using sleep apnea syndrome or apnea as keywords. Retrieved documents were analyzed using the database with its own statistical functions and histcite software ( version 8.12. 16) .Results Since 1992 the international scientific papers on the SAS study showed a gradual upward trend.The United States is a world leader in this field. Recent research has focused on vascular endothelial barrier function and repair, oxidative stress, inflammation, cognitive function, special populations such as the elderlyor children patients with SAS. Conclusion Clinical researchers have paid more attention to SAS than before, but there are still many important issues unresolved.

          Release date:2016-08-30 11:56 Export PDF Favorites Scan
        • Eugene Garfield: A Man Pursuing for Answers

          Eugene Garfield是美國著名的文獻信息檢索專家.他從一個普通用戶的觀點,提出如何高效率檢索最新信息的問題,并匠心獨運地將引文索引與文獻評價有機結合,創造了garfield原理,創建了SCI評價體系和美國科學信息研究所,并擔任首任主席.帶領他的團隊,經過半個世紀拼搏,使SCI在其他文獻索引工具中脫穎而出,被公認為是科學信息交流和信息科學的革命性創造.本文通過簡述引文檢索與信息科學領域發展史來介紹他充滿傳奇色彩的一生.

          Release date:2016-08-25 03:34 Export PDF Favorites Scan
        • Evidence-based science: structuring a convergence symbiosis system that breaks through transcends of disciplines

          Science is a system of knowledge that reflects the essential connections and laws of the objective world. Classification of disciplines is a subsystem of science, which involves the development of human cognition which evolved from the scientific category to the department of higher education, and then formation of a complex management system. Nowadays with the rapid development of science and technology which triggering numerous complex social problems, an increasing trend of scientific integration calls for multidisciplinary and interdisciplinary research and education. In the 1990s, evidence-based medicine was emerged in the self-doubting of medical science, and extended to other fields of medicine, health policy and social sciences, forming an interdisciplinary evidence-based science system. Evidence-based science is an embodiment of scientific integration, and also the carrier and mechanism of cross-disciplinary convergence. It attempts to break through barriers of disciplines and management, and promotes interdisciplinary research, during which it has encountered many difficulties due to limitations of traditional disciplines. Evidence-based science does not provide an intrusion or transformation of thinking paradigm into other disciplines, but rather an equal dialogue to promote broader discipline collaboration and a new round of self-improvement, so as to constantly explore novel methods and theories to solve emerging problems, achieve continuous improvement, and pursue excellence.

          Release date:2019-06-24 09:18 Export PDF Favorites Scan
        • Situation of application and funding of evidenced-based research projects on traditional Chinese medicine (TCM) of National Natural Science Foundation of China in 2019

          This paper introduces the application and funding of evidence-based research projects on traditional Chinese medicine (TCM) of the National Natural Science Foundation of China (NSFC) in 2019 in terms of clinical research and methodology research, summarizes the primary problems existing in evidence-based research on TCM, discusses the quality of evidence-based research on TCM in clinical research, highlights the characteristics of TCM and reveals the evidence-based methodology on TCM.

          Release date:2020-07-02 09:18 Export PDF Favorites Scan
        • Evaluation of projects funded by National Natural Science Foundation of China

          Objectives To analyze the status quo of projects on pension services funded by the National Natural Science Foundation of China (NSFC), with the aim of enlarging the perspective and horizon of related studies, and improving both the quantity and quality of such projects in NSFC. Methods NSFC website was systematically searched to collect information of pension service projects funded by NSFC from 2008 to 2017. SPSS 19.0 software was subsequently applied to analyze the characteristics of the projects in terms of study type, regional distribution, profession and institution, and fund scale, etc. Results A total of 39 projects on pension service were included, among which 12 were focused on related strategies (30.8%), 11 on related models (28.2%), and 6 on the effects of different interventions (15.4%). The 39 projects were unbalanced in terms of geographical distribution, institutions and research types. Conclusions NSFC should facilitate the research of pension service by expanding the related fund scale, increasing the fund support, strengthening the exchange of domestically different regions, and enhancing international cooperation.

          Release date:2019-01-15 09:51 Export PDF Favorites Scan
        • Science and Ethics in Conducting Cardiothoracic Surgery with Da Vinci Surgical System in China: A Systematic Review

          ObjectiveTo systematically evaluate the effectiveness, safety and ethics of Da Vinci Surigcal System (dVSS)in the field of cardiothoracic surgery, and provide evidence for its clinical application. MethodsWe searched VIP, CNKI, WanFang Database, CBM, official website of National Health and Family Planning Commission of People's Republic of China, PubMed, Cochrane Library, Google Scholar, WHO ICTRP search portal, ClinicalTrials.gov, Chinese Clinical Trial Registration Center, Australian-New Zealand Clinical Trials Registry and ISRCTN to collect clinical trials of dVSS for thoracic and cardiovascular diseases to evaluate its effectiveness, safety and ethics. The search time was from the establishment of each database to January 2014. The quality of included literatures was evaluated by Grades of Recommendations Assessment, Development and Evaluation (GRADE). ResultsA total of 31 studies were identified including 4 case control studies and 27 retrospective studies involving 1 037 patients. The quality of included literatures was all very low. dVSS had been widely used in cardiothoracic surgery including coronary artery bypass grafting, valvuloplasty or valve replacement, thoracic tumor resection, etc. Compared with conventional surgery and thoracoscopy, the safety and effectiveness of dVSS was good, while its economic burden was heavier for the patients. dVSS could benefit patients and improve clinical level of cardiothoracic surgery. The disciplines and qualification of dVSS application was legal, but the maturity of its clinical use needed improvement, and relevant measures were required. The ethics in the research, introduction and application of dVSS had some problems which deserved more attention. ConclusionsClinical use of dVSS in cardiothoracic surgery is relatively safe and effective, but research quality needs to be improved. More studies on the economics and ethics of dVSS are needed in the field of cardiothoracic surgery. Relevant measures of precaution, accountability and patient protection are required to further improve clinical application of dVSS in cardiothoracic surgery, and whole-process ethical supervision should be conducted with the help of existing clinical ethical review platform.

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        • Evidence-Based Research on Chinese Academic Journals Indexed by Six International Index Systems

          Objective To investigate the academic journals indexed by 6 international index systems so as to provide scientific evidence for the development of academic journals. Methods The principle and approach of evidence-based medicine were adopted. Information about Chinese academic journals indexed by 6 index systems was obtained by WEB searching and database retrieval. Details of academic journals in the charge of the Ministry of Education of China( MOE) were sought and assessed by six well-trained reviewers using a blind method. Results Seventy-six academic journals were indexed by SCI which was about 1.52% of total journals published in China and six of them were in the charge of MOE (about 1.46% of the total). Citation impact of academic papers indexed by ISI ranged from 0.9 to 2.2, and average impact ranged from 0.2 to 0.5. Approximately 4.8%, 1.6%, 1.28% and 11.32% academic journals were indexed by EI, IM, EM, AJ respectively. Conclusions The number of Chinese academic journals indexed by key international index systems was small, and the quality of journals should be greatly improved in future.

          Release date:2016-09-07 02:25 Export PDF Favorites Scan
        • Analysis of projects in liver transplantation by National Natural Sciences Foundation ofChina from 2010–2019

          ObjectiveIn order to provide a data base for fund project applicants and funding priorities, we would summarize the basic situation and key points of basic research in liver transplantation by analyzing the projects funded by the Natural Science Foundation of China (NSFC) in the field of liver transplantation.MethodsThrough the big data knowledge management and service platform of NSFC, internet-based science information system, and shared service network of NSFC, we searched the funding project information in the liver transplantation relevant field from 2010 to 2019, then analyzed the effectiveness of the Young Scientists Fund of NSFC in promoting young researchers and the research focus and development direction of funding projects.ResultsIn the latest 10 years, NSFC persistently and stably funded the basic research in the field of liver transplantation, with the total number of funding projects was 387, and the funding budget was 198.215 million yuan. The main types of funding projects were the General Program and the Youth Science Fund. There were 210 General Program project (54.3%) with an amount of 113.14 million yuan (57.1%), 127 Young Scientists Fund (32.8%) with an amount of 27.9 million yuan (14.1%), and 22 Fund for Less Developed Regions (5.7%) with an amount of 9.03 million yuan (4.6%). Sun Yat-sen University and Zhejiang University were far ahead of other supporting institutions in both the total number of projects undertaken and the amount of funds granted. The youth/surface ratio reached as high as 72.2% (13/18). The conversion rate of Young Scientists Fund to higher-level projects reached about 50%, which was significantly higher than the overall level of 24.7% (21/85) in the field of liver transplantation. The funding projects were mainly distributed in application code H0318 (liver regeneration, liver protection, liver failure, and artificial liver, 58, 15.0%), H0321 (organ transplantation of digestive system, 169, 43.7%), and H1006 (organ transplantation and transplantation immunity, 50, 12.9%). The main research fields were transplantation immunity and liver injury and liver protection. At the same time, projects such as graft function and complications of liver transplantation were also funded. There were few studies on the immune status of long-term survival in patients after liver transplantation and the mechanism on prevention of immunosuppressant-related diseases.ConclusionsThe NSFC has a great leading effect on the discipline development and talent cultivation of liver transplantation. However, there are still some problems in the discipline layout, such as the lack of attention to the mechanism of long-term graft function and chronic immune rejection.

          Release date:2021-02-08 07:10 Export PDF Favorites Scan
        • 成年山羊皮膚干細胞體外克隆與誘導分化

          Objective To establish a good method and culture system to isolate skin stem cell and expand it in vitro so as to lay a foundation for exploring the proliferation and differentiation mechanism of skin stem cell. Methods Skin stem cells were obtained by explant culture and identified by using alkaline phosphatase(ALP) staining and differentiating experiment in vitro. Stem cell was induced by the cocktail of conditional medium with cell growth factor (insulin like growth factor and epidermal growth factor). Results Skin stem cell colonies were derived from ear skin tissues of adult dairy goats. The colonies had some characteristics of embryonic stem cells, such as the ability to be continously passaged (Passage 5) and the morphology nest-like. They continued to be ALP positive and had the capacity of forming embryoid bodies. These cells were pluripotent and stem-like cells. In vitro these stem cell can be induced to be Follicle-like structure, Astrocyte-like cells, osteoblast-like cell. Conclusion Explant culture is a good method to isolate skin stem cell, which can be induced to be committed differentiation and trans-differentiation.

          Release date:2016-09-01 09:35 Export PDF Favorites Scan
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          2. 射丝袜