【Abstract】 Objective To investigate the survival rate, voiding, sexual function after nerve-sparing surgery with extended systematic extraperitoneal lateral lymphadenectomy in lower rectal cancer. Methods Three hundreds and ninety-two cases with advanced lower rectal cancer who underwent nerve-sparing surgery with radical dissection from 1996 to 2000 were reviewed. Among them,173 cases only cleared in abdominal cavity,219 cases coupled with extraperitoneal lateral lymphadenectomy. Results The metastatic rate of lateral lymph node was 17.8%(39/219),the rate of non-modal foci of metastatic disease in lateral out of the abdominal cavity was 5.9%(13/219).Local recurrence rate, the abdominal cavity group was 16.2%（28/173）; the coupled group was 9.6%（21/219）， P＜0.05. Conclusion By contrast,abdominal cavity coupled with extraperitoneal lympadenectomy acted to cut down local recurrence and to elevate 5-year survival rate,the postoperative quality of life with voiding, sexual function appeared to be seriously affected, although the radical dissection are nerve-sparing surgery.
Vascular aging is the common pathological basis of chronic diseases such as cardiovascular and cerebrovascular diseases, and its early intervention has important public health significance. The overall regulation theory of preventive treatment of disease in traditional Chinese medicine has significant advantages in the prevention and treatment of vascular aging. However, due to the lack of systematic consensus on diagnosis and treatment, the lack of standardization in syndrome differentiation, treatment and prevention has seriously hindered the standardized clinical application and the construction of collaborative diagnosis and treatment system of traditional Chinese and Western medicine. Based on the current evidence and clinical practice, the multidisciplinary expert team developed and registered the "Expert consensus on diagnosis and treatment of vascular aging with traditional Chinese medicine (2026)" aiming to clarify the standardized formulation path of the expert consensus.