Objective To generally analyse the current situations and advances in the biotherapy of gastric cancer. Methods The published papers about the current situations and research advances in the biotherapy of gastric cancer were reviewed. Results The main research fields and treatments in the biotherapy of gastric cancer include immunomodulator therapy, guided therapy of monoclonal antibodies and their jointbodies, cytokine therapy, adoptive immunotherapy and gene therapy, etc. Conclusion As a beneficial complement for surgery, chemotherapy and radiotherapy, biotherapy plays an important auxiliary role in the multiple treatments for gastric cancer.
自1987年Mouret完成世界首例腹腔鏡膽囊切除術以來，隨著外科醫生手術技術的不斷提高和腹腔鏡器械的逐漸改進，腹腔鏡微創技術的應用范圍越來越廣泛，以腹腔鏡為代表的微創外科已經成為21世紀外科發展的方向之一，其對胃腸道惡性腫瘤根治的可行性和手術安全性已經得到認可。已有多項RCT研究顯示，腹腔鏡結直腸癌手術與開腹手術具有相當的近、遠期療效，美國結直腸癌外科醫師協會已將其列為治療結直腸癌的標準手術方式之一。近年來，腹腔鏡在胃癌根治術中的應用已逐漸由早期胃癌擴展到進展期胃癌，并取得了與開腹手術相當的近、中期療效。但是人們對CO2 氣腹是否有利于胃腸道腫瘤的侵襲、轉移一直心存疑慮，隨之一些有關腹腔鏡技術中不同種類、不同壓力的氣腹與胃腸道腫瘤侵襲、轉移關系的研究報道相繼出現,不同學者報道結果有較大差異，有些學者認為CO2氣腹有利于胃腸道腫瘤的侵襲、轉移; 而有些學者卻認為CO2氣腹對胃腸道腫瘤的侵襲、轉移無顯著影響。..................