Experience of Treating Multiple Liver Cancer by Liver Resection Combined with Intraoperative Radiofrequency Ablation in the Same Period_West China Medical Journal

Authors：

 PengYonghai ¹ , ChenSirui ¹ ,  HuZhaohui ¹ , LuoHua ¹ , GuoDaoning ²

1. Department of Hepatobiliary Surgery, Mianyang Central Hospital, Mianyang, Sichuan 621000, P. R. China;
2. Department of Ultrasound, Mianyang Central Hospital, Mianyang, Sichuan 621000, P. R. China;

Corresponding?author：

HuZhaohui, Email: huzhaohui.sc@163.com

Keywords：

Multiple liver cancer; Liver resection; Radiofrequency ablation; Ultrasonography

DOI：

10.7507/1002-0179.201600334

Video：

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Objective To explore the value liver resection combined with intraoperative radiofrequency ablation during the same period in the treatment of multiple liver cancer. Methods We retrospectively analyzed the clinical data of 33 patients with multiple liver cancer treated between January 2005 and April 2013. All the patients were treated by liver resection combined with intraoperative radiofrequency ablation in the same period. There were 91 tumor foci in 33 patients, among which 39 tumor foci were surgically removed, and 52 tumor foci were radiofrequency ablated. Ultrasonography and enhanced CT/MRI were performed for the patients 1 year, 2 years and 3 years after surgery. Results No bleeding or death occurred during the operation. It was observed that the transient liver function was damaged after surgery, but it quickly returned to A level after treatment. All the patients had no perioperative death or other serious complications. Tumor recurrence rate was 16.1% in the first year, 48.4% in the second year and 93.5% in the third year after surgery. Conclusion Liver resection combined with intraoperative radiofrequency ablation for multiple liver cancer in the same period is feasible and safe, without increasing the average length of hospital stay, operative mortality rate and postoperative tumor recurrence rate.

Citation： PengYonghai, ChenSirui, HuZhaohui, LuoHua, GuoDaoning. Experience of Treating Multiple Liver Cancer by Liver Resection Combined with Intraoperative Radiofrequency Ablation in the Same Period. West China Medical Journal, 2016, 31(7): 1227-1230. doi: 10.7507/1002-0179.201600334 Copy

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13.	張輝, 徐新保, 何曉軍, 等. 原發性肝癌術后復發再手術切除與射頻消融治療的療效比較[J]. 西部醫學, 2013, 25(12):1816-1818.
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1. 陳孝平, 汪建平. 外科學[M]. 8版. 北京:人民衛生出版社, 2013:432-435.
2. Chen MS, Li JQ, Zheng Y, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma[J]. Ann Surg, 2006, 243(3):321-328.
3. Beeres M, Loch M, Schulz B, et al. Bolus timing in high-pitch CT angiography:feasibility study[J]. Euro J Radiol, 2013, 82(6):1028-1033.
4. Tatsugami F, Matsuki M, Inada Y, et al. Feasibility of low-volume injections of contrast material with a body weight-adapted iodine-dose protocol in 320-detector row coronary CT angiography[J]. Acad Radiol, 2010, 17(2):207-211.
5. El-Serag HB, Marrero JA, Rudolph L, et al. Diagnosis and treatment of hepatocelluar carcinoma[J]. Gastroenterology, 2008, 134(6):1752-1763.
6. Takayama T, Makuuchi M, Hirohashi S, et al. Early hepatocellular carcinoma as an entity with a high rate of surgical cure[J]. Hepatology, 1998, 28(5):1241-1246.
7. Schiff ER, Sorrell MF, Maddrey WC. 希夫肝臟病學[M]. 北京:化學工業出版社, 2006:1240-1241.
8. 楊學偉, 將小峰, 曹良啟, 等. 肝切除聯合射頻消融治療多發性肝癌36例療效分析[J]. 實用醫學雜志, 2013, 29(11):1820-1822.
9. 覃夏川, 周翔. 肝葉切除聯合術中超聲引導射頻消融治療多發性肝癌的價值[J]. 臨床超聲醫學雜志, 2013, 15(10):713-714.
10. 馮鉅濤, 李君, 方天翎, 等. 肝切除并微波消融與TACE治療多發性肝癌的療效比較[J]. 廣州醫學院學報, 2012, 40(2):41-44.
11. 朱倩, 喬國梁, 晏建軍, 等. 乙肝肝硬化相關早期肝癌切除術預后[J]. 中華肝膽外科雜志, 2014, 20(4):258-264.
12. 彭國文, 李曉群. 射頻消融及組合方案治療特殊/高危部位肝癌的中遠期療效[J]. 介入放射學雜志, 2013, 22(6):525-528.
13. 張輝, 徐新保, 何曉軍, 等. 原發性肝癌術后復發再手術切除與射頻消融治療的療效比較[J]. 西部醫學, 2013, 25(12):1816-1818.
14. 吳孟超. 原發性肝癌外科綜合治療的現狀和展望[J]. 中華外科雜志, 2004, 42(1):13-15.
15. 張城碩, 富大智, 張佳林, 等. 復發性小肝癌視頻與再次手術切除臨床療效的Meta分析[J]. 中華肝膽外科雜志, 2014, 20(4):248-252.

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West China Medical Journal

Experience of Treating Multiple Liver Cancer by Liver Resection Combined with Intraoperative Radiofrequency Ablation in the Same Period

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