Risk factor analysis for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy_Chinese Journal of Ocular Fundus Diseases

Authors：

CaoDan ,  ZhangLiang , HuangZhongning , 王軍 , 尹東明 , 孟倩麗 , 牛勇毅 , 胡云燕

Department of Ophthalmology, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510080, China;

Corresponding?author：

ZhangLiang, Email: zhangliang1@medmail.com.cn

Keywords：

Diabetic retinopathy/surgery; Glaucoma, neovascular/etiology; Vitrectomy

DOI：

10.3760/cma.j.issn.1005-1015.2015.02.009

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Objective To investigate the risk factors for neovascular glaucoma (NVG) after vitrectomy in proliferative diabetic retinopathy (PDR) patients. Methods Three hundred and one patients (301 eyes) with PDR who underwent vitrectomy between January 2008 and December 2013 in our hospital were retrospectively evaluated. Risk factors for NVG after vitrectomy were identified by multivariate Logistic regression analysis. Results Twelve of 301 patients (4.0%) developed postoperative NVG in 2 to 18 months after vitrectomy. The incidence of postoperative NVG peaked in 2 to 6 months after vitrectomy (7 eyes, 58.3%). Logistic regression analysis showed that postoperative retinal detachment was a significant risk factor for postoperative NVG in eyes with PDR (P < 0.001). Eyes with postoperative retinal detachment were more likely to develop NVG after vitrectomy than those without postoperative retinal detachment (OR=17.826). Gender, age, duration of diabetes, preoperative serum creatinine levels, glycated hemoglobin levels, preoperative intraocular pressure, preoperative lens status, combined phacoemulsification surgery and tamponade were not associated with postoperative NVG (P > 0.05). Conclusion Postoperative retinal detachment is a major risk factor for NVG after vitrectomy in PDR.

Citation： CaoDan, ZhangLiang, HuangZhongning. Risk factor analysis for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy. Chinese Journal of Ocular Fundus Diseases, 2015, 31(2): 147-149. doi: 10.3760/cma.j.issn.1005-1015.2015.02.009 Copy

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7.	Goto A, Inatani M, Inoue T, et al. Frequency and risk factors for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy[J]. J Glaucoma, 2013, 22(7):572-576.
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11.	王穎, 江楓, 韓金棟, 等.玻璃體腔硅油或C₃F₈填充對增生型糖尿病視網膜病變并發單純玻璃體積血玻璃體切割手術療效的影響[J].中華眼底病雜志, 2014, 30(2):148-151.
12.	Lucke K. Silicone oil in surgery of complicated retinal detachment[J]. Ophthalmologe, 1993, 90(3):215-238.
13.	陶勇, 姜燕榮, 黎曉新, 等.增殖型糖尿病視網膜病變玻璃體手術與虹膜紅變的關系[J].中華糖尿病雜志, 2005, 13(5):332-334.
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1. 施愛群.2型糖尿病病程與視網膜病變關系的探討[J].中華眼底病雜志, 2003, 19(2):59-60.
2. Blankenship GW, Machemer R.Long-term diabetic vitrectomy results:report of 10 year follow-up[J]. Ophthalmology, 1985, 92(4):503-506.
3. Summanen P. Neovascular glaucoma following vitrectomy for diabetic eye disease[J].Acta Ophthalmol, 1988, 66(1):110-116.
4. Oldendoerp J, Spitznas M. Factors influencing the results of vitreous surgery in diabetic retinopathy.Ⅰ. Iris rubeosis and/or active neovascularization at the fundus[J]. Graefe's Arch Clin Exp Ophthalmol, 1989, 227(1):1-8.
5. Sima P, Zoran T.Long-term results of vitreous surgery for proliferative diabetic retinopathy[J]. Doc Ophthalmol, 1994, 87(3):223-232.
6. Kumagai K, Furukawa M, Ogino N, et al. Long-term followup of vitrectomy for diffuse nontractional diabetic macular edema[J]. Retina, 2009, 29:(4)464-472.
7. Goto A, Inatani M, Inoue T, et al. Frequency and risk factors for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy[J]. J Glaucoma, 2013, 22(7):572-576.
8. Hutton WL, Pesicka GA, Fuller DG. Cataract extraction in the diabetic eye after vitrectomy[J]. Am J Ophthalmol, 1987, 104(1):1-4.
9. Sadiq SA, Chatterjee A, Vernon SA. Progression of diabetic retinopathy and rubeotic glaucoma following cataract surgery[J]. Eye(Lond), 1995, 9 (Pt 6):728-738.
10. Lahey JM, Francis RR, Kearney JJ. Combining phacoemulsification with pars plana vitrectomy in patients with proliferative diabetic retinopathy:a series of 223 cases[J].Ophthalmology, 2003, 110(7):1335-1339.
11. 王穎, 江楓, 韓金棟, 等.玻璃體腔硅油或C₃F₈填充對增生型糖尿病視網膜病變并發單純玻璃體積血玻璃體切割手術療效的影響[J].中華眼底病雜志, 2014, 30(2):148-151.
12. Lucke K. Silicone oil in surgery of complicated retinal detachment[J]. Ophthalmologe, 1993, 90(3):215-238.
13. 陶勇, 姜燕榮, 黎曉新, 等.增殖型糖尿病視網膜病變玻璃體手術與虹膜紅變的關系[J].中華糖尿病雜志, 2005, 13(5):332-334.
14. Helbig H, Kellner U, Bornfeld N, et al. Rubeosis iridis after vitrectomy for diabetic retinopathy[J]. Graefe's Arch Clin Exp Ophthalmol, 1998, 236(10):730-733.

Chinese Journal of Ocular Fundus Diseases

Risk factor analysis for neovascular glaucoma after vitrectomy in eyes with proliferative diabetic retinopathy

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