Strengthen the construction of tertiary prevention and treatment network of retinopathy of prematurity in China_Chinese Journal of Ocular Fundus Diseases

Authors：

 Chen Changzheng , Wang Xiaoling

Eye Center of the Renmin Hospital of Wuhan University, Wuhan 430000, China;

Corresponding?author：

Chen Changzheng, Email: whuchenchzh@163.com

Keywords：

Retinopathy of prematurity; Preventive medicine; Editorial

DOI：

10.3760/cma.j.cn511434-20220525-00322

Video：

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Abstract Full text Figures/Tables Video References Cited by

The prevention and treatment of retinopathy of prematurity (ROP) is an important strategic content of blindness prevention and treatment in China. Medical institutions including remote areas have strengthened the awareness of neonatal fundus screening, however, there are problems of vague screening standards, mainly manifested in expanding the scope of screening and even universal screening of newborns. At the same time, all kinds of fundus changes found in the examination cannot be correctly interpreted and handled, which increase the economic and psychological burden of children's families. In addition, with the wide application of intravitreal injection of anti-neovascular endothelial growth factor, problems such as improper grasp of indications and improper treatment of complications have become increasingly prominent. At this stage, it is urgent to strengthen the construction of ROP prevention and control network, which is suitable for China's national conditions, led by the government and coordinated participation of health and medical institutions at all levels.

Citation： Chen Changzheng, Wang Xiaoling. Strengthen the construction of tertiary prevention and treatment network of retinopathy of prematurity in China. Chinese Journal of Ocular Fundus Diseases, 2022, 38(7): 526-530. doi: 10.3760/cma.j.cn511434-20220525-00322 Copy

1.	中華醫學會眼科學分會眼底病學組. 中國早產兒視網膜病變篩查指南(2014年)[J]. 中華眼科雜志, 2014, 50(12): 933-935. DOI: 10.3760/cma.j.issn.0412-4081.2014.12.017.Fundus Disease Group of Ophthalmology Branch of Chinese Medical Association. Guidelines for Retinopathy of Prematurity Screening in China (2014)[J]. Chin J Ophthalmol, 2014, 50(12): 933-935. DOI: 10.3760/cma.j.issn.0412-4081.2014.12.017.
2.	Hellstr?m A, Smith LE, Dammann O. Retinopathy of prematurity[J]. Lancet, 2013, 382(9902): 1445-1457. DOI: 10.1016/S0140-6736(13)60178-6.
3.	王雨生, 張自峰, 李曼紅, 等. 西安地區早產兒視網膜病變篩查的初步結果[J]. 中華眼科雜志, 2010, 46(2): 119-124. DOI: 10.3760/cma.j.issn.0412-4081.2010.02.006.Wang YS, Zhang ZF, Li HM, et al. Preliminary results of screening of retinopathy of prematurity in Xi'an[J]. Chin J Ophthalmol, 2010, 46(2): 119-124. DOI: 10.3760/cma.j.issn.0412-4081.2010.02.006.
4.	張國明, 曾鍵, 黃麗娜, 等. 深圳早產兒視網膜病變篩查結果分析[J]. 中華眼底病雜志, 2008, 24(1): 38-40.Zhang GM, Zeng J, Huang LN, et al. Screening results of retinopathy of prematurity in preterm infants in 3 hospitals in Shenzhen[J]. Chin J Ocul Fundus Dis, 2008, 24(1): 38-40.
5.	蘇鈺, 陳長征, 李璐, 等. 湖北地區早產兒視網膜病變篩查結果及相關因素分析[J]. 中華眼底病雜志, 2012, 28(1): 53-56. DOI: 10.3760/cma.j.issn.1005-1015.2012.01.014.Su Y, Cheng CZ, Li L, et al. Screening and risk factors analysis of retinopathy of prematurity in Hubei[J]. Chin J Ocul Fundus Dis, 2012, 28(1): 53-56. DOI: 10.3760/cma.j.issn.1005-1015.2012.01.014.
6.	趙家良. “視覺2020”行動與我國防盲治盲工作[J]. 中華眼科雜志, 2002, 38(10): 577-579. DOI: 10.3760/j:issn:0412-4081.2002.10.001.Zhao JL. "Vision 2020" and prevention of blindness in China[J]. Chin J Ophthalmol, 2002, 38(10): 577-579. DOI: 10.3760/j:issn:0412-4081.2002.10.001.
7.	瑪依努爾·于蘇甫, 王寧利. “視覺2020”: 中國防盲治盲與眼健康工作進展[J]. 中華醫學雜志, 2020, 100(48): 3831-3834. DOI: 10.3760/cma.j.cn112137-20200825-02468.Mayinuer YSF, Wang NL. "Vision 2020": the progress of blindness prevention and eye health in China[J]. Natl Med J China, 2020, 100(48): 3831-3834. DOI: 10.3760/cma.j.cn112137-20200825-02468.
8.	黎曉新. 重視早產兒視網膜病變的防治[J]. 中華眼科雜志, 2005, 41(4): 289-291. DOI: 10.3760/j:issn:0412-4081.2005.04.001.Li XX. Emphasizing the prevention and treatment for retinopathy of prematurity[J]. Chin J Ophthalmol, 2005, 41(4): 289-291. DOI: 10.3760/j:issn:0412-4081.2005.04.001.
9.	趙培泉, 張琦, 許宇. 提高小兒視網膜疾病的認知水平, 推動我國小兒視網膜疾病研究的深入開展[J]. 中華眼底病雜志, 2014, 30(1): 1-5. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.001.Zhao PQ, Zhang Q, Xu Y. The diagnosis and treatment of pediatric retinal disease[J]. Chin J Ocul Fundus Dis, 2014, 30(1): 1-5. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.001.
10.	王雨生, 李蓉. 重視我國早產兒視網膜病變的防治工作[J]. 中華眼科雜志, 2011, 47(6): 483-486. DOI: 10.3760/cma.j.issn.0412-4081.2011.06.002.Wang YS, Li R. Pay attention to the prevention and treatment of retinopathy of prematurity in China[J]. Chin J Ophthalmol, 2011, 47(6): 483-486. DOI: 10.3760/cma.j.issn.0412-4081.2011.06.002.
11.	陸方. 開展小兒視網膜疾病影像檢查, 提高小兒視網膜疾病診斷治療水平[J]. 中華眼底病雜志, 2014, 30(1): 9-11. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.003.Lu F. Imaging technology and the diagnosis and treatment of pediatric retinal disease[J]. Chin J Ocul Fundus Dis, 2014, 30(1): 9-11. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.003.
12.	兒童眼及視力保健技術規范[J]. 中華眼科雜志, 2013, 49(7): 651-652. DOI: 10.3760/cma.j.issn.0412-4081.2013.07.017.Technical specification for children's eye and vision care[J]. Chin J Ophthalmol, 2013, 49(7): 651-652. DOI: 10.3760/cma.j.issn.0412-4081.2013.07.017.
13.	Emerson MV, Pieramici DJ, Stoessel KM, et al. Incidence and rate of disappearance of retinal hemorrhage in newborns[J]. Ophthalmology, 2001, 108(1): 36-39. DOI: 10.1016/s0161-6420(00)00474-7.
14.	Callaway NF, Ludwig CA, Blumenkranz MS, et al. Retinal and optic nerve hemorrhages in the newborn infant: one-year results of the newborn eye screen test study[J]. Ophthalmology, 2016, 123(5): 1043-1052. DOI: 10.1016/j.ophtha.2016.01.004.
15.	李麗紅, 李娜, 盧軍, 等. 昆明市婦幼保健院新生兒眼病篩查4年回顧[J]. 中國婦幼保健雜志, 2015, 30(18): 2686-2690. DOI: 10.7620/zgfybj.j.issn.1001-4411.2015.18.33.Li LH, Li N, Lu J, et al. Review of neonatal eye disease screening in Kunming Maternal and Child Health Hospital in 4 years[J]. Maternal & Child Health Care of China, 2015, 30(18): 2686-2690. DOI: 10.7620/zgfybj.j.issn.1001-4411.2015.18.33.
16.	張建萍, 馬金瑜, 韋麗芳, 等. 新生兒眼底出血及其相關影響因素分析[J]. 中華眼底病雜志, 2015, 31(2): 153-156. DOI: 10.3760/cma.j.issn.1005-1015.2015.02.011.Zhang JP, Ma JY, Wei LF, et al. Retinal hemorrhages in newborns and associated factors[J]. Chin J Ocul Fundus Dis, 2015, 31(2): 153-156. DOI: 10.3760/cma.j.issn.1005-1015.2015.02.011.
17.	杜婉麗, 吳彩云, 張瑜, 等. 足月新生兒眼底出血的高危因素分析[J]. 中國斜視與小兒眼科雜志, 2017, 25(2): 6-9. DOI: 10.3969/J.ISSN.1005-328X.2017.02.002.Du WL, Wu CY, Zhang Y, et al. The high-risk factors for newborn fundus hemorrhages[J]. Chinese Journal of Strabismus & Pediatric Ophthalmology, 2017, 25(2): 6-9. DOI: 10.3969/J.ISSN.1005-328X.2017.02.002.
18.	朱文琿, 駱榮江, 劉韶瑞. 高危新生兒眼底出血臨床分析[J]. 中華眼底病雜志, 2012, 28(5): 482-484. DOI: 10.3760/cma.j.issn.1005-1015.2012.05.012.Zhu WH, Luo RJ, Liu SR. Clinical analysis of retinal hemorrhages in high-risk infants[J]. Chin J Ocul Fundus Dis, 2012, 28(5): 482-484. DOI: 10.3760/cma.j.issn.1005-1015.2012.05.012.
19.	Egge K, Lyng G, Maltau JM. Retinal haemorrhages in the newborn[J]. Acta Ophthalmol (Copenh), 1980, 58(2): 231-236. DOI: 10.1111/j.1755-3768.1980.tb05715.x.
20.	Egge K, Lyng G, Maltau JM. Effect of instrumental delivery on the frequency and severity of retinal hemorrhages in the newborn[J]. Acta Obstet Gynecol Scand, 1981, 60(2): 153-155.
21.	Watts P, Maguire S, Kwok T, et al. Newborn retinal hemorrhages: a systematic review[J]. J AAPOS, 2013, 17(1): 70-78. DOI: 10.1016/j.jaapos.2012.07.012.
22.	Von Barsewisch B. Perinatal retinal haemorrhages: morphology, aetiology, and significance[M]. New York: Springer-Verlag, 1979: 71-118.
23.	Berkus MD, Ramamurthy RS, O'Connor PS, et al. Cohort study of silastic obstetric vacuum cup deliveries: Ⅰ. safety of the instrument[J]. Obstet Gynecol, 1985, 66(4): 503-509.
24.	李麗紅, 張國明, 李娜, 等. 新生兒視網膜出血分級標準探討[J]. 中國婦幼保健, 2017, 32(15): 3572-3574. DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.15.60.Li LH, Zhang GM, Li N, et al. Discussion on the grading standard of neonatal retinal hemorrhage[J]. Maternal & Child Health Care of China, 2017, 32(15): 3572-3574. DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.15.60.
25.	Tang H, Li N, Li Z, et al. Collaborating group of neonatal ocular birth defects and genetic diseases in China. Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study[J]. Br J Ophthalmol, 2018, 102(12): 1742-1746. DOI: 10.1136/bjophthalmol-2018-312366.
26.	馬燕, 鄧光達, 麻婧, 等. 嬰幼兒眼病篩查中視網膜白色病灶的病因初探[J]. 眼科, 2018, 27(3): 211-214. DOI: 10.13281/j.cnki.issn.1004-4469.2018.03.011.Ma Y, Deng GD, Ma J, et al. Preliminary investigation of retinal white changes in infants' ocular screenings[J]. Ophthalmol CHN, 2018, 27(3): 211-214. DOI: 10.13281/j.cnki.issn.1004-4469.2018.03.011.
27.	尹虹, 黎曉新, 趙明威, 等. 早產兒視網膜病變激光治療的療效分析[J]. 眼科研究, 2007, 25(3): 208-210. DOI: 10.3760/cma.j.issn.2095-0160.2007.03.014.Yin H, Li XX, Zhao MW, et al. Treatment outcome of retinopathy of premeturity by laser photocoagulation[J]. Chin Ophthal Res, 2007, 25(3): 208-210. DOI: 10.3760/cma.j.issn.2095-0160.2007.03.014.
28.	尹虹, 黎曉新, 梁建宏, 等. 影響1區早產兒視網膜病變激光治療結果的因素分析[J]. 中華眼底病雜志, 2010, 26(1): 58-60. DOI: 10.3760/cma.j.issn.1005-1015.2010.01.15.Yin H, Li XX, Liang JH, et al. Analysis on factors influencing for results of laser treatment of zone one retinopathy of premature[J]. Chin J Ocul Fundus Dis, 2010, 26(1): 58-60. DOI: 10.3760/cma.j.issn.1005-1015.2010.01.15.
29.	VanderVeen DK, Melia M, Yang MB, et al. Anti-vascular endothelial growth factor therapy for primary treatment of type 1 retinopathy of prematurity: a report by the American Academy of Ophthalmology[J]. Ophthalmology, 2017, 124(5): 619-633. DOI: 10.1016/j.ophtha.2016.12.025.
30.	??mez A, Karakü?ük Y, ?zmen MC, et al. The results of intravitreal bevacizumab monotherapy for treating aggressive posterior retinopathy of prematurity and type 1 retinopathy of prematurity[J]. Eye (Lond), 2021, 35(12): 3302-3310. DOI: 10.1038/s41433-021-01413-4.
31.	Honda S, Hirabayashi H, Tsukahara Y, et al. Acute contraction of the proliferative membrane after an intravitreal injection of bevacizumab for advanced retinopathy of prematurity[J]. Graefe's Arch Clin Exp Ophthalmol, 2008, 246(7): 1061-1063. DOI: 10.1007/s00417-008-0786-7.
32.	Huang Q, Zhang Q, Xu Y, et al. Asymmetric outcomes of type 1 retinopathy of prematurity after bilateral intravitreal ranibizumab treatment[J/OL]. J Ophthalmol, 2017, 2017: 1741386[2017-05-22]. https://pubmed.ncbi.nlm.nih.gov/28341474/. DOI: 10.1155/2017/1741386.
33.	Van Geest RJ, Lesnik-Oberstein SY, Tan HS, et al. A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy[J]. Br J Ophthalmol, 2012, 96(4): 587-590. DOI: 10.1136/bjophthalmol-2011-301005.
34.	王雨生. 我國早產兒視網膜病變三級防治網建設的設想與實踐[J]. 中華眼底病雜志, 2014, 30(1): 6-8. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.002.Wang YS. Ideas and practices of construction of tertiary prevention network of retinopathy of prematurity in China[J]. Chin J Ocul Fundus Dis, 2014, 30(1): 6-8. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.002.
35.	Mukherjee AN, Watts P, Al-Madfai H, et al. Impact of retinopathy of prematurity screening examination on cardiorespiratory indices: a comparison of indirect ophthalmoscopy and retcam imaging[J]. Ophthalmology, 2006, 113(9): 1547-1552. DOI: 10.1016/j.ophtha.2006.03.056.
36.	Chiang MF, Wang L, Busuioc M, et al. Telemedical retinopathy of prematurity diagnosis: accuracy, reliability, and image quality[J]. Arch Ophthalmol, 2007, 125(11): 1531-1538. DOI: 10.1001/archopht.125.11.1531.
37.	Roth DB, Morales D, Feuer WJ, et al. Screening for retinopathy of prematurity employing the retcam 120: sensitivity and specificity[J]. Arch Ophthalmol, 2001, 119(2): 268-272.

1. 中華醫學會眼科學分會眼底病學組. 中國早產兒視網膜病變篩查指南(2014年)[J]. 中華眼科雜志, 2014, 50(12): 933-935. DOI: 10.3760/cma.j.issn.0412-4081.2014.12.017.Fundus Disease Group of Ophthalmology Branch of Chinese Medical Association. Guidelines for Retinopathy of Prematurity Screening in China (2014)[J]. Chin J Ophthalmol, 2014, 50(12): 933-935. DOI: 10.3760/cma.j.issn.0412-4081.2014.12.017.
2. Hellstr?m A, Smith LE, Dammann O. Retinopathy of prematurity[J]. Lancet, 2013, 382(9902): 1445-1457. DOI: 10.1016/S0140-6736(13)60178-6.
3. 王雨生, 張自峰, 李曼紅, 等. 西安地區早產兒視網膜病變篩查的初步結果[J]. 中華眼科雜志, 2010, 46(2): 119-124. DOI: 10.3760/cma.j.issn.0412-4081.2010.02.006.Wang YS, Zhang ZF, Li HM, et al. Preliminary results of screening of retinopathy of prematurity in Xi'an[J]. Chin J Ophthalmol, 2010, 46(2): 119-124. DOI: 10.3760/cma.j.issn.0412-4081.2010.02.006.
4. 張國明, 曾鍵, 黃麗娜, 等. 深圳早產兒視網膜病變篩查結果分析[J]. 中華眼底病雜志, 2008, 24(1): 38-40.Zhang GM, Zeng J, Huang LN, et al. Screening results of retinopathy of prematurity in preterm infants in 3 hospitals in Shenzhen[J]. Chin J Ocul Fundus Dis, 2008, 24(1): 38-40.
5. 蘇鈺, 陳長征, 李璐, 等. 湖北地區早產兒視網膜病變篩查結果及相關因素分析[J]. 中華眼底病雜志, 2012, 28(1): 53-56. DOI: 10.3760/cma.j.issn.1005-1015.2012.01.014.Su Y, Cheng CZ, Li L, et al. Screening and risk factors analysis of retinopathy of prematurity in Hubei[J]. Chin J Ocul Fundus Dis, 2012, 28(1): 53-56. DOI: 10.3760/cma.j.issn.1005-1015.2012.01.014.
6. 趙家良. “視覺2020”行動與我國防盲治盲工作[J]. 中華眼科雜志, 2002, 38(10): 577-579. DOI: 10.3760/j:issn:0412-4081.2002.10.001.Zhao JL. "Vision 2020" and prevention of blindness in China[J]. Chin J Ophthalmol, 2002, 38(10): 577-579. DOI: 10.3760/j:issn:0412-4081.2002.10.001.
7. 瑪依努爾·于蘇甫, 王寧利. “視覺2020”: 中國防盲治盲與眼健康工作進展[J]. 中華醫學雜志, 2020, 100(48): 3831-3834. DOI: 10.3760/cma.j.cn112137-20200825-02468.Mayinuer YSF, Wang NL. "Vision 2020": the progress of blindness prevention and eye health in China[J]. Natl Med J China, 2020, 100(48): 3831-3834. DOI: 10.3760/cma.j.cn112137-20200825-02468.
8. 黎曉新. 重視早產兒視網膜病變的防治[J]. 中華眼科雜志, 2005, 41(4): 289-291. DOI: 10.3760/j:issn:0412-4081.2005.04.001.Li XX. Emphasizing the prevention and treatment for retinopathy of prematurity[J]. Chin J Ophthalmol, 2005, 41(4): 289-291. DOI: 10.3760/j:issn:0412-4081.2005.04.001.
9. 趙培泉, 張琦, 許宇. 提高小兒視網膜疾病的認知水平, 推動我國小兒視網膜疾病研究的深入開展[J]. 中華眼底病雜志, 2014, 30(1): 1-5. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.001.Zhao PQ, Zhang Q, Xu Y. The diagnosis and treatment of pediatric retinal disease[J]. Chin J Ocul Fundus Dis, 2014, 30(1): 1-5. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.001.
10. 王雨生, 李蓉. 重視我國早產兒視網膜病變的防治工作[J]. 中華眼科雜志, 2011, 47(6): 483-486. DOI: 10.3760/cma.j.issn.0412-4081.2011.06.002.Wang YS, Li R. Pay attention to the prevention and treatment of retinopathy of prematurity in China[J]. Chin J Ophthalmol, 2011, 47(6): 483-486. DOI: 10.3760/cma.j.issn.0412-4081.2011.06.002.
11. 陸方. 開展小兒視網膜疾病影像檢查, 提高小兒視網膜疾病診斷治療水平[J]. 中華眼底病雜志, 2014, 30(1): 9-11. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.003.Lu F. Imaging technology and the diagnosis and treatment of pediatric retinal disease[J]. Chin J Ocul Fundus Dis, 2014, 30(1): 9-11. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.003.
12. 兒童眼及視力保健技術規范[J]. 中華眼科雜志, 2013, 49(7): 651-652. DOI: 10.3760/cma.j.issn.0412-4081.2013.07.017.Technical specification for children's eye and vision care[J]. Chin J Ophthalmol, 2013, 49(7): 651-652. DOI: 10.3760/cma.j.issn.0412-4081.2013.07.017.
13. Emerson MV, Pieramici DJ, Stoessel KM, et al. Incidence and rate of disappearance of retinal hemorrhage in newborns[J]. Ophthalmology, 2001, 108(1): 36-39. DOI: 10.1016/s0161-6420(00)00474-7.
14. Callaway NF, Ludwig CA, Blumenkranz MS, et al. Retinal and optic nerve hemorrhages in the newborn infant: one-year results of the newborn eye screen test study[J]. Ophthalmology, 2016, 123(5): 1043-1052. DOI: 10.1016/j.ophtha.2016.01.004.
15. 李麗紅, 李娜, 盧軍, 等. 昆明市婦幼保健院新生兒眼病篩查4年回顧[J]. 中國婦幼保健雜志, 2015, 30(18): 2686-2690. DOI: 10.7620/zgfybj.j.issn.1001-4411.2015.18.33.Li LH, Li N, Lu J, et al. Review of neonatal eye disease screening in Kunming Maternal and Child Health Hospital in 4 years[J]. Maternal & Child Health Care of China, 2015, 30(18): 2686-2690. DOI: 10.7620/zgfybj.j.issn.1001-4411.2015.18.33.
16. 張建萍, 馬金瑜, 韋麗芳, 等. 新生兒眼底出血及其相關影響因素分析[J]. 中華眼底病雜志, 2015, 31(2): 153-156. DOI: 10.3760/cma.j.issn.1005-1015.2015.02.011.Zhang JP, Ma JY, Wei LF, et al. Retinal hemorrhages in newborns and associated factors[J]. Chin J Ocul Fundus Dis, 2015, 31(2): 153-156. DOI: 10.3760/cma.j.issn.1005-1015.2015.02.011.
17. 杜婉麗, 吳彩云, 張瑜, 等. 足月新生兒眼底出血的高危因素分析[J]. 中國斜視與小兒眼科雜志, 2017, 25(2): 6-9. DOI: 10.3969/J.ISSN.1005-328X.2017.02.002.Du WL, Wu CY, Zhang Y, et al. The high-risk factors for newborn fundus hemorrhages[J]. Chinese Journal of Strabismus & Pediatric Ophthalmology, 2017, 25(2): 6-9. DOI: 10.3969/J.ISSN.1005-328X.2017.02.002.
18. 朱文琿, 駱榮江, 劉韶瑞. 高危新生兒眼底出血臨床分析[J]. 中華眼底病雜志, 2012, 28(5): 482-484. DOI: 10.3760/cma.j.issn.1005-1015.2012.05.012.Zhu WH, Luo RJ, Liu SR. Clinical analysis of retinal hemorrhages in high-risk infants[J]. Chin J Ocul Fundus Dis, 2012, 28(5): 482-484. DOI: 10.3760/cma.j.issn.1005-1015.2012.05.012.
19. Egge K, Lyng G, Maltau JM. Retinal haemorrhages in the newborn[J]. Acta Ophthalmol (Copenh), 1980, 58(2): 231-236. DOI: 10.1111/j.1755-3768.1980.tb05715.x.
20. Egge K, Lyng G, Maltau JM. Effect of instrumental delivery on the frequency and severity of retinal hemorrhages in the newborn[J]. Acta Obstet Gynecol Scand, 1981, 60(2): 153-155.
21. Watts P, Maguire S, Kwok T, et al. Newborn retinal hemorrhages: a systematic review[J]. J AAPOS, 2013, 17(1): 70-78. DOI: 10.1016/j.jaapos.2012.07.012.
22. Von Barsewisch B. Perinatal retinal haemorrhages: morphology, aetiology, and significance[M]. New York: Springer-Verlag, 1979: 71-118.
23. Berkus MD, Ramamurthy RS, O'Connor PS, et al. Cohort study of silastic obstetric vacuum cup deliveries: Ⅰ. safety of the instrument[J]. Obstet Gynecol, 1985, 66(4): 503-509.
24. 李麗紅, 張國明, 李娜, 等. 新生兒視網膜出血分級標準探討[J]. 中國婦幼保健, 2017, 32(15): 3572-3574. DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.15.60.Li LH, Zhang GM, Li N, et al. Discussion on the grading standard of neonatal retinal hemorrhage[J]. Maternal & Child Health Care of China, 2017, 32(15): 3572-3574. DOI: 10.7620/zgfybj.j.issn.1001-4411.2017.15.60.
25. Tang H, Li N, Li Z, et al. Collaborating group of neonatal ocular birth defects and genetic diseases in China. Fundus examination of 199 851 newborns by digital imaging in China: a multicentre cross-sectional study[J]. Br J Ophthalmol, 2018, 102(12): 1742-1746. DOI: 10.1136/bjophthalmol-2018-312366.
26. 馬燕, 鄧光達, 麻婧, 等. 嬰幼兒眼病篩查中視網膜白色病灶的病因初探[J]. 眼科, 2018, 27(3): 211-214. DOI: 10.13281/j.cnki.issn.1004-4469.2018.03.011.Ma Y, Deng GD, Ma J, et al. Preliminary investigation of retinal white changes in infants' ocular screenings[J]. Ophthalmol CHN, 2018, 27(3): 211-214. DOI: 10.13281/j.cnki.issn.1004-4469.2018.03.011.
27. 尹虹, 黎曉新, 趙明威, 等. 早產兒視網膜病變激光治療的療效分析[J]. 眼科研究, 2007, 25(3): 208-210. DOI: 10.3760/cma.j.issn.2095-0160.2007.03.014.Yin H, Li XX, Zhao MW, et al. Treatment outcome of retinopathy of premeturity by laser photocoagulation[J]. Chin Ophthal Res, 2007, 25(3): 208-210. DOI: 10.3760/cma.j.issn.2095-0160.2007.03.014.
28. 尹虹, 黎曉新, 梁建宏, 等. 影響1區早產兒視網膜病變激光治療結果的因素分析[J]. 中華眼底病雜志, 2010, 26(1): 58-60. DOI: 10.3760/cma.j.issn.1005-1015.2010.01.15.Yin H, Li XX, Liang JH, et al. Analysis on factors influencing for results of laser treatment of zone one retinopathy of premature[J]. Chin J Ocul Fundus Dis, 2010, 26(1): 58-60. DOI: 10.3760/cma.j.issn.1005-1015.2010.01.15.
29. VanderVeen DK, Melia M, Yang MB, et al. Anti-vascular endothelial growth factor therapy for primary treatment of type 1 retinopathy of prematurity: a report by the American Academy of Ophthalmology[J]. Ophthalmology, 2017, 124(5): 619-633. DOI: 10.1016/j.ophtha.2016.12.025.
30. ??mez A, Karakü?ük Y, ?zmen MC, et al. The results of intravitreal bevacizumab monotherapy for treating aggressive posterior retinopathy of prematurity and type 1 retinopathy of prematurity[J]. Eye (Lond), 2021, 35(12): 3302-3310. DOI: 10.1038/s41433-021-01413-4.
31. Honda S, Hirabayashi H, Tsukahara Y, et al. Acute contraction of the proliferative membrane after an intravitreal injection of bevacizumab for advanced retinopathy of prematurity[J]. Graefe's Arch Clin Exp Ophthalmol, 2008, 246(7): 1061-1063. DOI: 10.1007/s00417-008-0786-7.
32. Huang Q, Zhang Q, Xu Y, et al. Asymmetric outcomes of type 1 retinopathy of prematurity after bilateral intravitreal ranibizumab treatment[J/OL]. J Ophthalmol, 2017, 2017: 1741386[2017-05-22]. https://pubmed.ncbi.nlm.nih.gov/28341474/. DOI: 10.1155/2017/1741386.
33. Van Geest RJ, Lesnik-Oberstein SY, Tan HS, et al. A shift in the balance of vascular endothelial growth factor and connective tissue growth factor by bevacizumab causes the angiofibrotic switch in proliferative diabetic retinopathy[J]. Br J Ophthalmol, 2012, 96(4): 587-590. DOI: 10.1136/bjophthalmol-2011-301005.
34. 王雨生. 我國早產兒視網膜病變三級防治網建設的設想與實踐[J]. 中華眼底病雜志, 2014, 30(1): 6-8. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.002.Wang YS. Ideas and practices of construction of tertiary prevention network of retinopathy of prematurity in China[J]. Chin J Ocul Fundus Dis, 2014, 30(1): 6-8. DOI: 10.3760/cma.j.issn.1005-1015.2014.01.002.
35. Mukherjee AN, Watts P, Al-Madfai H, et al. Impact of retinopathy of prematurity screening examination on cardiorespiratory indices: a comparison of indirect ophthalmoscopy and retcam imaging[J]. Ophthalmology, 2006, 113(9): 1547-1552. DOI: 10.1016/j.ophtha.2006.03.056.
36. Chiang MF, Wang L, Busuioc M, et al. Telemedical retinopathy of prematurity diagnosis: accuracy, reliability, and image quality[J]. Arch Ophthalmol, 2007, 125(11): 1531-1538. DOI: 10.1001/archopht.125.11.1531.
37. Roth DB, Morales D, Feuer WJ, et al. Screening for retinopathy of prematurity employing the retcam 120: sensitivity and specificity[J]. Arch Ophthalmol, 2001, 119(2): 268-272.

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