ObjectiveTo evaluate the value of myocardial perfusion change before and after coronary artery bypass grafting (CABG) in predicting postoperative major adverse cardiovascular events (MACE).MethodsA total of 70 CABG patients who received CABG completed by the same operator from January to November 2017 were selected, including 45 males and 25 females with an average age of 64.83±9.09 years. The patients were divided into two groups according to whether the patients had MACE after 1 year of the surgery, including a non-MACE group (group A, n=60) and a MACE group (group B, n=10). The clinical data of patients were compared.ResultsThere were statistical difference in the myocardial contrast echocardiography (MCE) score in the group A before and after surgery (P<0.05), and there were statistically significant differences in the left ventricular size and left ventricular ejection fraction (LVEF) value before and 1 year after surgery (P<0.001), but no statistically significant difference in the size of left atrium (P=0.075). There was no significant difference in the preoperative and postoperative MCE score, and preoperative and postoperative 1-year cardiac ultrasound score in the group B (P>0.05).ConclusionThe change of myocardial perfusion after CABG surgery is associated with postoperative MACE. The evaluation of myocardial perfusion before and after CABG surgery is of great significance for the prognosis evaluation of patients.
Objective To explore the predictive value of the advanced lung cancer inflammation index (ALI) for major adverse cardiovascular events (MACE) in patients undergoing transcatheter aortic valve replacement (TAVR). Methods A retrospective analysis was conducted on patients with severe aortic stenosis who underwent TAVR at the Department of Cardiology, West China Hospital of Sichuan University between April 2012 and September 2023. The primary endpoint was MACE. Participants were stratified into different subgroups based on the cutoff value of ALI. Kaplan-Meier survival analysis was used to evaluate the differences in prognosis, and the Cox proportional hazards regression model and restricted cubic spline analysis were used to analyze the relationship between ALI and the risk of MACE. Results A total of 1752 patients were included, with a median follow-up of 2.46 years. In the fully adjusted Cox regression model, each unit increase in ALI was associated with a 2% reduction in the risk of MACE [hazard ratio (HR)=0.98, 95% confidence interval (CI) (0.97, 0.99), P<0.001]. Additionally, compared with the ALI<39.58 group, the ALI≥39.58 group had a 59% lower risk of MACE [HR=0.41, 95%CI (0.30, 0.55), P<0.001]. The restricted cubic spline model indicated a linear relationship between ALI and the risk of MACE (P for overall<0.001, P for non-linear=0.652). Conclusion ALI is significantly associated with MACE in patients after TAVR; ALI≤39.58 is an independent risk factor and can be used as a prognostic indicator for preoperative risk stratification and treatment decision-making.