ObjectiveTo review the current research and application progress of three-dimentional (3D) printed porous titanium alloy after tumor resection, and provide direction and reference for the follow-up clinical application and basic research of 3D printed porous titanium alloy. MethodsThe related literature on research and application of 3D printed porous titanium alloy after tumor resection in recent years was reviewed from three aspects: performance of simple 3D printed porous titanium alloy, application analysis of simple 3D printed porous titanium alloy after tumor resection, and research progress of anti-tumor 3D printed porous titanium alloy. Results3D printing technology can adjust the pore parameters of porous titanium alloy, so that it has the same biomechanical properties as bone. Appropriate pore parameters are conducive to inducing bone growth, promoting the recovery of skeletal system and related functions, and improving the quality of life of patients after operation. Simple 3D printed porous titanium alloy can more accurately match the bone defect after tumor resection through preoperative personalized design, so that it can closely fit the surgical margin after tumor resection, and improve the accuracy and efficiency of the operation. The early and mid-term follow-up results show that its application reduces the postoperative complications such as implant loosening, subsidence, fracture and so on, and enhances the bone stability. The anti-tumor performance of 3D printed porous titanium alloy mainly includes coating and drug-loading treatment of pure 3D printed porous titanium alloy, and some progress has been made in the basic research stage. ConclusionSimple 3D printed porous titanium alloy is suitable for patients with large and complex bone defects after tumor resection, and the anti-tumor effect of 3D printed porous titanium alloy can be achieved through coating and drug delivery.
Ultra-high molecular weight polyethylene (UHMWPE) fiber has emerged as a critical material advancing the development of minimally invasive medical devices, owing to its exceptional specific strength, outstanding wear resistance, and inherent bio-inertia. We systematically review the current application landscape of UHMWPE fibers in minimally invasive medicine, highlighting their broad use in orthopedic sutures and fixation systems, reinforcement layers for cardiovascular interventional devices, cables to drive surgical robots, and materials in frontier neural interfaces. These applications underscore the material’s core advantages across diverse scenarios. However, its broader clinical translation faces multiple challenges, including surface bio-inertia, long-term dynamic durability, difficulty in processing, and a lack of standardization. To address these challenges, this article delves into comprehensive strategies encompassing surface engineering, composite material development, structural optimization, and intelligent control algorithms. Looking forward, UHMWPE fibers are poised to evolve towards intelligence and functional integration. Through deep convergence with flexible electronics and data-driven research, coupled with the establishment of robust standardization systems, UHMWPE fibers are expected to play an even more pivotal role in the next generation of advanced minimally invasive medical devices, ultimately propelling the field towards greater precision and personalization.