Objective To investigate the relationship between skin/pectoral muscle invasion and the prognosis of male breast cancer. Methods Clinical data and follow-up information of 79 male breast cancer patients who received treatment between September 2008 to April 2020 in West China Hospital were retrospectively reviewed, to analyze the clinicopathological features of male breast cancer and prognostic value of skin/pectoral muscle invasion. Results Among 79 male breast cancer patients, a total of 23 patients (29.1%) were with skin/pectoral muscle invasion at diagnosis. All the patients were followed up, with a median follow-up period of 63.3 months (1.0–204.5 months). Within follow-up period, 8 patients (10.1%) suffered from relapse, 19 patients (24.7%, 19/77) suffered from metastasis, and 4 patients (5.1%) died. Multivariate Cox proportional risk regression model suggested that patients with skin/pectoral muscle invaded had poor disease free survival [RR=4.48, 95%CI (1.08, 18.52), P=0.038]. Conclusions Skinor pectoral muscle invasion might be a valuable prognostic factor for male breast cancer patients. However, limited by sample size, the conclusion should be proved by further high-level studies.
Objective To collect and analyze the qualitative studies on patients’ compliance with hypertension management in the community, and to summarize the factors influencing the compliance from the view of patients. Methods Eleven electronic databases and search strategies and words were determined through discussion by experts and the review group. After the selection and critical appraisal of the retrieved studies were performed by two reviewers independently, meta-summary was employed for the results of qualitative studies. Results Five studies were included. The results showed some factors had great impact on the compliance of patients, including patients’ knowledge of hypertension and its treatment, doctor-patient relationship, patients’ financial status, social support, designing of treatment plans, and patients’ individual conditions. Conclusion To improve doctors’ technical competence, building good doctor-patient relationship, strengthening patients’ individualized health education, formulating the proper treatment plan, and making good use of the social support system would promote the compliance with hypertension management in the community.
Objective To investigate the microbial contamination status of ultrasonic coupling gel and probe surfaces in hospital, and to provide a scientific basis for the prevention and control of infections related to ultrasonic examinations. Methods A cluster sampling combined with convenience sampling method was adopted. In March 2025, three departments in Suining Central Hospital with high-frequency ultrasound examinations, namely the Physical Examination Center, Ultrasonic Imaging Department and Emergency Department of the hospital, were selected for sampling for 2 consecutive weeks, which covered the morning and afternoon of working days from Monday to Friday. Microbial culture and counting were conducted on the ultrasound probes for intact skin contact, which were standby after routine cleaning and disinfection in the departments, as well as the in-use ultrasonic coupling gel. Meanwhile, the dominant bacterial strains cultured were identified. Results A total of 168 samples of standby ultrasonic probes and 129 samples of in-use ultrasonic coupling gel were collected. The total colony count qualified rate of standby ultrasonic probes was 44.64% (75/168), with 58.67% (44/75) in the Physical Examination Center, 57.14% (8/14) in the Emergency Department, and 29.11% (23/79) in the Ultrasonic Imaging Department. There was a statistically significant difference in the qualified rate of probes among different departments (P<0.05). The total colony count qualified rate of in-use ultrasonic coupling gel samples was 29.46% (38/129), including 50.00% (3/6) in the Emergency Department, 33.33% (15/45) in the Physical Examination Center, and 25.64% (20/78) in the Ultrasonic Imaging Department. There was no statistically significant difference in the qualified rate of coupling gel among different departments (P>0.05). Bacterial species identification showed that the types of contaminating bacteria in in-use ultrasonic coupling gel and standby ultrasonic probes were similar, mainly Burkholderia pyrrocinia accounting for 65.76% (121/184), Burkholderia stabilis accounting for 28.80% (53/184). Pseudomonas aeruginosa, Staphylococcus aureus, and mold were not detected. Conclusions The standby ultrasonic probes and in-use ultrasonic coupling gel in the hospital have microbial contamination, with Burkholderia cepacia complex as the main contaminating bacteria. This poses a risk of nosocomial infection and requires further strengthening of management.