【摘要】 目的 利用首過時間技術進行全胰腺CT灌注掃描，了解正常胰腺CT灌注的特點。 方法 2006年6月-2007年3月， 64例正常胰腺患者行64排螺旋CT灌注掃描，測量胰頭、胰體及胰尾的灌注值、強化峰值、達峰時間和血容量。分別按患者的性別、年齡及胰腺測量的部位分組，將灌注參數進行統計分析。 結果 ①男性胰腺的血容量高于女性（Plt;0.05），其余灌注參數在兩性間差異無統計學意義（Pgt;0.05）。②41~60歲組的灌注值低于lt;40歲組和gt;60歲組；gt;60歲組的強化峰值高于41~60歲組；41~60歲組的達峰時間長于lt;40歲組；gt;60歲組的血容量高于41~60歲組（Plt;0.05）。③胰體和胰尾的灌注值高于胰頭（Plt;0.05），其余灌注參數在胰腺不同部位差異無統計學意義。 結論 正常胰腺血流狀況在不同性別、不同年齡段及不同部位存在差異，首過時間技術應用于正常胰腺能反映這些特征。【Abstract】 Objective To investigate the CT perfusion features of normal pancreas with first-pass technique with 64-MDCT. Methods Perfusion CT was performed on 64 patients with normal pancreas from June 2006 to March 2007. Four perfusion parameters, including perfusion, peak enhancement, time to peak, and blood volume, were obtained at the head, body and tail of the pancreas. Perfusion parameters were compared between different sexes, among different age groups and among different sites. Results ① Blood volume of male was significantly higher than that of female (Plt;0.05). ② The perfusion value in the age group of 41-60 was significantly lower than that in the age group of lt;40 and gt;60 (Plt;0.05). The peak enhancement in the age group of gt;60 was significantly higher than that in the age group of 41-60 (Plt;0.05). The time to peak in the age group of 41-60 was significantly longer than that in the age group of lt;40 (Plt;0.05). The blood volume in the age group of gt;60 was significantly higher than that in the age group of 41-60 (Plt;0.05). ③The perfusion values of the body and the tail were significantly higher than that of the head (Plt;0.05). Conclusion There are significant differences in the perfusion parameters between different sexes and among several age groups and sites. The first-pass technique of perfusion applied in normal pancreas can reflect these features.
Cardiac magnetic resonance T2* mapping technique is a gradient echoes relaxation recovery sequence, being used to measure the iron metabolism abnormality clinically, such as myocardial iron of hemorrhage in acute myocardial infarction reperfusion injury, transfusion-dependent anemia, hemochromatosis and so on, which is supposed to be the main quantitative evaluation method for myocardial iron overload or deficiency with critical clinical value. This paper summarizes the technical and post-processing points of cardiac magnetic resonance T2* mapping and its clinical applications in diseases related to abnormal myocardial iron metabolism.
ObjectiveTo investigate the high-resolution computed tomography (HRCT) signs of patients diagnosed with the coronavirus disease 2019 (COVID-19) and explore its evolution features during hospitalization.MethodsFrom January 17, 2020 to February 26, 2020, HRCT images from 15 COVID-19 patients were analyzed. All the patients had positive nucleic acid test results of SARS-CoV-2. The imaging features of initial and follow-up of each patient were reviewed and graded based on the severity of lung lesions.ResultsAmong the 15 COVID-19 patients, ground-glass opacity (GGO) was found in 14 cases. Six patients presented with consolidation and 3 with fibrosis. Five patients had multi-lobe involvement. Subpleural distribution pattern was present in 12 patients (80.0%) and peribronchovascular distribution pattern was present in 2 patients (13.3%). The severity score on HRCT images at the follow-up was significantly higher than that at the initial (4.6±3.4 vs. 3.5±2.5, P=0.018 2). Increase of random distribution pattern (5 cases) were also noted at the follow-up.ConclusionsChest HRCT of COVID-19 patients is characterized with GGO mainly distributed in subpleural areas and a rapid progression within a short time interval. HRCT could provide a sensitive monitor to observe disease progression for COVID-19 patients.