目的:觀察W-F168-B型和RENATRONⅡ型透析器復用機臨床應用對患者透析質量的影響。方法:符合納入標準的受試者隨機分為2組,試驗組和對照組的透析器分別用W-F168-B和RENATRONⅡ復用。測定受試者透析前后血紅蛋白、白蛋白、肌酐、尿素氮,計算尿素清除率除以分布容積(Kt/V,K為尿素清除率,t為透析時間,V為分布容積)。結果用均數±標準差表示,采用成組設計的t檢驗,spss13.0統計軟件包分析。結果:試驗組和對照組Kt/V值分別為1.25±0.26和1.24±0.19,透析前后血紅蛋白差值分別為(1.32±0.14)g/L和(1.34±0.27)g/L,白蛋白差值分別為(0.86±0.05)g/L和(0.79±0.18)g/L。t 檢驗示兩組以上各值比較差異無統計學意義(Pgt;0.05)。結論:兩種透析器復用機對受試者透析充分性的影響無明顯差異,能達到較好的透析質量。
ObjectivesTo systematically review the influence for catheter mechanical dysfunction of different peritoneal dialysis catheterization methods.MethodsPubMed, EMbase, The Cochrane Library, CNKI, WanFang Data and VIP databases were searched to collect randomized controlled trials (RCTs) and cohort studies on comparisons of different peritoneal dialysis catheterization from inception to March 31st, 2018. Two reviewers independently screened literature, extracted data and assessed risk of bias of included studies. Network meta-analysis was then performed by using ADDIS 1.16.6 software.ResultsA total of 33 studies (9 RCTs and 24 cohort studies) involving 3 301 patients were included. Network meta-analysis showed that the incidence of catheter mechanical dysfunctionwas the least and had statistically significant difference compared with that in percutaneous catheterization (OR=3.60; 95%CI, 1.64 and 15.38) and open surgery catheterization (OR=5.86; 95%CI, 2.68 and 14.53). Percutaneous catheterization was superior to open surgery catheterization, but there was no significant difference.ConclusionsLaparoscopic catheterization may be the best technique for catheter insertion in peritoneal dialysis considering catheter dysfunction. Each technology has its own advantages. Choice of insertion method should be based on the characteristics of both the patient and the insertion techniques.