ObjectiveTo compare the therapeutic effect between intramedullary fixation and external fixation on intertrochanteric fracture. MethodsBetween June 2005 and June 2011, 32 patients with Evans-Jensen type Ⅲ intertrochanteric fracture were treated with proximal femoral nail anti-rotation (PFNA), Gamma nail, dynamic hip screw plate (DHS) or locking compression plate (LCP), separately. The operation duration, peri-operative bleeding, load time, Harris hip score and postoperative complications were observed in the patients, and were used to analyze the therapeutic effect among the four methods. ResultsShorter operation duration, less bleeding in the surgery, smaller quantity of drainage after the operation (P<0.05) were found in group Gamma and group PFNA compared with those in group DHS and LCP. The duration of hospitalization didn't differ much between the two fixation systems (P>0.05). The difference in operation duration, operative bleeding and post-operative drainage between group Gamma and PFNA, and between group DHS and LCP was not significant (P>0.05). ConclusionThe intramedullary fixation was better than external fixation for Evans-Jensen type Ⅲ intertrochanteric fracture.