目的 分析多功能空氣消毒機在普通內科病房的動態消毒效果，為病房空氣質量的控制提供參考依據。 方法 2010年9月－2011年4月對普通內科病房在動態狀態下進行細菌檢測并使用多功能空氣消毒機消毒，并就消毒前后的空氣細菌菌落總數進行分析比較。 結果 在動態狀態下，病房關門關窗并開啟空調機時，使用多功能空氣消毒機消毒前的空氣細菌菌落總數顯著高于消毒后，差異有統計學意義（P＜0.05）；病房在開門開窗時，使用多功能空氣消毒機消毒前后的空氣細菌菌落總數比較，差異無統計學意義（P＞0.05）。 結論 普通內科病房在關門關窗并開啟空調機動態狀態下，使用多功能空氣消毒機可以降低空氣細菌菌落總數，改善房間空氣質量。
In recent years, pathogenic metagenomic next-generation sequencing (mNGS) technology has become more and more widely used in the field of clinical infection. Driven by clinical needs, mNGS technology is constantly being optimized and developed. From manual operation to automated process, from simple qualitative detection to quantitative monitoring, from infection identification to multi-dimensional diagnosis of “infection+tumor”, certain research results have been achieved. Of course, there are still some limitations in clinical application of this technology. For example, there are many mNGS detection related reagents in China, but a systematic and complete quality management control and evaluation system has not been established. Further research is needed. This article summarizes the development and application of pathogen metagenomic sequencing technology in recent years, as well as the standardization and normalized process of mNGS detection, in order to provide a reference for pathogen mNGS sequencing to better assist clinical infection diagnosis.