Physical agent therapy is the core means of early rehabilitation and chronic disease intervention, but the clinical selection is currently not standardized. This article is based on the unique mechanisms of action of different physical agents, and systematically explores how to accurately select physical agent interventions for different systemic diseases, in order to achieve the goals of inhibiting pathological processes, enhancing drug efficacy, reducing medical costs, minimizing drug side effects, and reducing patient burden with individual or synergistic drugs. The aim is to provide practical reference for clinical workers to accurately select physical agent therapies and promote the standardization and efficiency of rehabilitation treatment.
Focused low-intensity pulsed ultrasound (FLIPUS), as a non-invasive physical therapy, is widely used in orthopedics, neurosurgery, urology, rehabilitation medicine and other clinical specialties. More and more studies have found that FLIPUS can treat knee osteoarthritis (KOA) by promoting tissue regeneration, relieving pain and inhibiting inflammation, improve the common clinical symptoms of KOA, such as joint pain or stiffness, limited joint activity and decreased walking function, and improve the quality of life of patients to a certain extent. This article mainly reviews the effect and biophysical mechanism of FLIPUS in the treatment of KOA, as well as related clinical research, in order to provide a reference for clinical workers who carry out research in this field.