【摘要】 目的 探討全自動尿沉渣分析儀在尿管型檢測中的應用。 方法 收集尿管型患者晨尿標本836份。所有標本均經尿干化學分析儀檢測Pro≥1+或尿沉渣分析儀提示有管型。采用UF100全自動尿沉渣分析儀和顯微鏡檢測管型，對比分析兩者的檢測結果。 結果 836份標本中，UF100全自動尿沉渣分析儀檢測陽性者320例，占38.28%；顯微鏡檢測陽性者195例，占23.33%。其中UF100全自動尿沉渣分析儀的假陽性率為26.52%，假陰性率為23.08%。UF100尿沉渣分析儀與顯微鏡檢測管型的陽性結果比較，差異有統計學意義（Plt;0.01）。 結論 UF100全自動尿沉渣儀能快速篩檢尿沉渣，但存在一定的假陰性，必須同時將其檢測結果與尿干化學結果結合考慮以決定是否再進行顯微鏡檢測，減少假陰性以防止漏檢。【Abstract】 Objective To investigate the application of UF-100 full-auto urine sediment analyzer in detecting cylindruia. Methods 836 specimens with cylindruia were selected. All the specimens with Pro≥1+ were dectected by chemical dipstick or cylindruia by urine sediment analyzer. The cast were detected by urine sediment analyzer and microscope, and the results were compared. Results Of 836 specimens, 320 positive samples(38.28%) were found by UF-100 while 195 (23.33%) were found by microscope. False positive rate and false negative rate of UF100 were 26.52% and 23.08%. Compared the results of urine sediment analyzer with microscope, the difference was statistically significant (Plt;0.01). Conclusions UF100 can detect urinary cast quickly, but there is a little high false negative rate. So we should consider urine sample whether to be detected by microscope compared with results of UF100 and chemical dipstick.
ObjectiveTo quantify the global burden of chronic obstructive pulmonary disease (COPD) attributable to high temperature, low temperature, and non-optimal temperatures from 1990 to 2021 using Global Burden of Disease (GBD) 2021 data. MethodsWe analyzed global, regional, and national COPD mortality and disability-adjusted life years (DALYs) attributable to high, low, and non-optimal temperatures. Joinpoint regression, age-period-cohort modeling, and Bayesian prediction models were employed. ResultsGlobally, age-standardized mortality rates (ASMRs) and DALY rates for COPD attributable to low temperature and non-optimal temperatures declined. However, the burden from high temperature increased. Low temperature consistently exerted a greater burden than high temperature across all metrics. Significant geographical disparities emerged: high-temperature mortality was highest in South Asia; low-temperature burden was most severe in East Asia; and high-income North America exhibited accelerated high-temperature mortality growth. The highest low-temperature burden occurred in middle-SDI regions, while high-temperature impacts predominated in low-middle-SDI regions. Age patterns showed rising high-temperature burden in the 15-39 age group and increasing low-temperature burden among adults aged ≥80 years. Bayesian projections revealed divergent gender trajectories: a continuing decline in low-temperature burden for males versus a decelerated decline for females (2020-2030). ConclusionLow temperature exposure remains the primary risk factor for COPD within non-optimal temperatures globally, although high-temperature impacts are increasing. Significant regional variations necessitate targeted interventions for three key populations: older adults vulnerable to cold, working-age adults with occupational heat exposure, and older women requiring rehabilitative support.