Counterproductive work behavior (CWB) is an employee’s spontaneous behavior that is potentially threatening to the interests of the organization itself or members of the organization. It is very common in organizations and is extremely harmful. The CWB of medical staff is extremely risky and can cause many adverse effects on the economy, society and patient health. Through reading and analyzing literature, the review discusses the concept, measurement, influencing factors and behavioral consequences of the medical staff CWB, and proposes coping strategies for improvement from the social, hospital, and individual levels. The aim is to provide a reference for reducing the CWB of medical staff and to improve medical quality and safety.