Objective To investigate the effects of children’s crawling-promotion-training-robot on gross motor function and cognitive function in children with global developmental delay (GDD). Methods A total of 40 children with GDD admitted to the Department of Rehabilitation Medicine, Children’s Hospital of Nanjing Medical University were selected as the research subjects. By envelope method, the children were randomly and equally divided into experimental group and control group, with 20 cases in each group. The experimental group received children’s crawling-promotion-training-robot combined with conventional rehabilitation therapy, while the control group received manual crawling training combined with conventional rehabilitation therapy. Before and after treatment, the scores of Gross Motor Function Measure Scale-88 (GMFM-88) and Gesell Developmental Scale (GDS) were respectively used to evaluate gross motor function and cognitive function. Results There was no significant difference in gender (χ2=0.100, P=0.752) and age (t=0.053, P=0.962) between the two groups. Before treatment, there was no significant difference in GMFM-88 and GDS scores between the two groups (P>0.05). After treatment, there were statistically significant differences in GMFM-88 and GDS scores between the two groups (P<0.05). The comparison within the group showed that there were statistically significant differences in GMFM-88 and GDS scores between the two groups before and after treatment. Conclusion Children’s crawling-promotion-training-robot is more effective than manual crawling training in improving gross motor function and cognitive function in children with GDD.
GB/T 21415－2025 is identical to ISO 17511: 2020 and replaces GB/T 21415－2008. It extends metrological traceability requirements from calibrators and control materials to values assigned to human samples, and introduces enhanced elements such as maximum allowable expanded measurement uncertainty, validation of metrological traceability, commutability assessment, and international harmonization protocols. This article systematically reviews the scope, general requirements, and the six calibration hierarchy structures of the standard. It focuses on key implementation aspects including the definition of the measurand, selection of reference systems, uncertainty budget allocation, and commutability. In addition, it clarifies the responsibilities and requirements for in vitro diagnostic medical device manufacturers, reference material producers, reference measurement laboratories, and medical laboratories, aiming to help relevant institutions establish applicable and verifiable value-transfer chains and to promote accuracy, comparability and mutual recognition of test results.