Kinesio taping is a technique which applies elastic patches on the body surface in a specific way to produce mechanical and neurophysiological effects, so as to support and protect the musculoskeletal system and improve the motor function of patients with various chronic musculoskeletal conditions. In addition, Kinesio taping has become popular among physiotherapists and showed certain clinical effect in the treatment of other fields such as neurological and pediatric rehabilitation in recent years, however its physiological mechanism is still unclear. This article puts forward some thinking and prospect on the basis of the review of clinical research and application of Kinesio taping, aiming to provide a reference for the research of clinical application and physiological mechanism of this technology.