Magnetic ferrite nanoparticles (MFNPs) have great application potential in biomedical fields such as magnetic resonance imaging, targeted drugs, magnetothermal therapy and gene delivery. MFNPs can migrate under the action of a magnetic field and target specific cells or tissues. However, to apply MFNPs to organisms, further modifications on the surface of MFNPs are required. In this paper, the common modification methods of MFNPs are reviewed, their applications in medical fields such as bioimaging, medical detection, and biotherapy are summarized, and the future application directions of MFNPs are further prospected.
Objective To generally analyse the current situations and advances in the biotherapy of gastric cancer. Methods The published papers about the current situations and research advances in the biotherapy of gastric cancer were reviewed. Results The main research fields and treatments in the biotherapy of gastric cancer include immunomodulator therapy, guided therapy of monoclonal antibodies and their jointbodies, cytokine therapy, adoptive immunotherapy and gene therapy, etc. Conclusion As a beneficial complement for surgery, chemotherapy and radiotherapy, biotherapy plays an important auxiliary role in the multiple treatments for gastric cancer.