Using paired t-test statistical analysis,authors studied the features of hemorrheology in 13 cases of anterior uveitis,16 cases of pan-uveitis,and 15 cases of Behccedil;et' syndrome.The study showed that serous viscocity(at 230 s-1)in anterior uveitis patient group was higher than that of the control group,P＜0.02; that blood viscocity at high shear rate(230 s-1)in pan-uneitis patient group was markedly elevated and the difference between patient and control group was sighificant,P＜0.005; and that blood viscocity at both high(230 s-1)and low shear rate(5.75 s-1)in Behcet' syndrome grou was elevated,and the differences were significant as compared to the controls(P＜0.01,P＜0.05).the high blood viscocity in uveitis and Behcet' syndrome patients was analyzed and discussed in the paper.We thought that the treatment for uveitis and Behcet' syndrome should include lowering blood viscocity and improving the plasticity of red blood cells. （Chin J Ocul Fundus Dis,1993,9:70-72）
Experimental uveitis was induced in rabbits by bovine serum albumin. Ocular inflammation,protein content of aqueous humor,T lymphocyte transformation and serum circulating immune complex were reduced markedly after the treatment of tetrandrine (Tet, 50mg/kg/d,ip)and dexamethasone(Dex, 5mg/kg/d,ip)for 8 days. Four days after withdrawal of Tet and Dex the protien content of the aqueous humor and serum eiucrlating immune complexes rose again,but these parameters in Tet group is lower than that in Dex group. The pathological study showed that inflammation of choroid in Tet treated group was lighter than that in untreated group. These results suggest that Tet is an effective inhibitory agent on bovine serum albumin-induced experimental uveitis. Its mechanism may be related to the suppression of cellular and humoral immune function aside from antiinflammation. （Chin J Ocul Fundus Dis,1994,10:149-152）
Using the techniques of monoclonal antibody and radioactive isotope,we found that the total glueosides of paeony (TGP) could almost regain peripheral blood T cell subsets increased or decreased ,supressed cellular immune function and disordered humor immune function of the patients with endogenous uveitis(ElJ) to normal level ,but could not regain those evidently of the patients in control group. The result suggested that TGP might possess double immunomodulatory effect on the patients with EU. （Chin J Ocul Fundus Dis,1994,10:146-148）
Objective To investigate the expression and significance of T-bet in experimental autoimmune uveoretinitis (EAU). Methods EAU was induced in 24 Lewis rats by immunization with retinal S-antigen (50 μg) and complete Freund′s adjuvant, and another 4 rats were the healthy control. The rats with EAU were executed 7, 12, 15, 21 days after immunization, respectively. Immunohistochemical single and double staining were performed using monoclonal antibodies of T-bet or CD4 on the ocular wholemounts and the consecutive sections of the eye and spleen from both 24 immunized Lewis rats and 4 normal controls. The positive cells were counted under the optic microscope and the data were analyzed by SPSS 11.0 statistic software. Results A few T-bet positive cells were observed in the normal ocular tissues and spleen. The expressions of T-bet in the iris, retina, and spleen increased 7 days after immunization, reached the peak at the 15th day, and decreased at the 21st day, which were higher than those in the control. Double staining on the consecutive sections revealed that most of the T-bet positive cells were positive for CD4 monoclona l antibody. Conclusion T-bet may affect the occurrence of EAU by activating Th1 cells. (Chin J Ocul Fundus Dis，2004，20：172-174)
One hundred and thirty patients with uveitis in north-western zone of our country were analyzed based on anatomical classification and their causes. It was found that anterior uveitis was the commonest type in uveitis,accounting for 86.15% of total patients. Intermediate uveitis, pan-uveitis and posterior uveitis accounted repectively for 6.92%, 3.85%and3.08% of the total patients. Rheumatic arthritis was the most frequently accompanied systemic disease in patients with uveitis,showing a possibly causative link between them in their pathogenesis. （Chin J Ocul Fundus Dis,1994,10:156-158）