The cyclodialysis cleft is a rare disease characterized by ocular hypotony and vision loss. Gonioscopy, ultrasound biomicroscopy and anterior segment optical coherence tomography are used to evaluate the cleft before treatment. The evaluation of cyclodialysis clefts provide a basis for the selection of treatment and the evaluation of effect. Current popular therapeutic approaches for cyclodialysis clefts include medical management, laser photocoagulation, transscleral diathermy, cryotherapy, cyclopexy and so on. Medical treatment is effective in small-size cyclodialysis cleft. But the indications and course of medical treatment remains controversial. Although laser photocoagulation, transscleral diathermy and cryotherapy are effective to treat cyclodialysis clefts in some cases, there are some risks, such as ocular damage, uncertainty about the effect and so on. Cyclopexy is the principal method for cyclodialysis clefts that failed to respond to conservative management, including extraocular cyclopexy, intraocular cyclopexy and cyclopexy under endoscopic. The modified cyclopexy is effective which reduces the surgical risk. For keeping the lens, intraocular cyclopexy and cyclopexy under endoscopic are not suitable. Vitrectomy combined with other method for cyclodialysis is effective for cyclodialysis clefts which combined with serious posterior segment damage.