目的總結近年來胰源性門靜脈高壓(pancreatic portal hypertension,PPH)的相關研究,以期能對其進行更及時、更有效的診斷和治療。方法在中國知網、PubMed等數據庫中搜索PPH的病因及機制研究、臨床特征、診斷標準和治療方法相關研究的文獻并作一綜述。結果PPH的發生與胰腺區域的解剖結構有關,主要病因為胰腺炎癥和胰腺腫瘤;其診斷由于臨床表現不具有特征性,需借助相關輔助檢查進行診斷。PPH的治療主要針對胰腺本身疾病和門靜脈高壓,其中針對門靜脈高壓的治療又分為合并或者不合并消化道出血的情況,在臨床上應根據不同的情況采取不同的治療措施。結論目前臨床上對PPH的診治手段比較成熟,但其預防性治療尚存在較大的爭議,這將是今后的研究重點。
【摘要】 目的 比較脛骨平臺骨折術后輔助與不輔助持續被動運動(continuous passive motion,CPM)的臨床療效。 方法 對2008年6月-2009年6月86例行手術治療的閉合性、無合并損傷的脛骨平臺骨折患者進行回顧性分析。根據是否輔助CPM分為CPM組27例和非CPM組(對照組)59例。對兩組患者的傷口愈合情況,膝關節屈曲、伸直角度,以及膝關節功能恢復情況進行比較。 結果 兩組傷口甲級愈合率差異無統計學意義(P=0.566)。在術后2周和6周,CPM組患者的膝關節屈曲角度明顯大于對照組(Plt;0.001),但在術后3個月和12個月,兩組的差異無統計學意義(P=0.219,P=0.512)。在術后2、6周,3、12個月,CPM組和對照組患者的膝關節伸直角度差異無統計學意義。在術后12個月的Rasmussen膝關節功能評分方面,CPM組和對照組的差異無統計學意義。 結論 脛骨平臺骨折術后輔助CPM能早期提升膝關節屈曲角度,但并不能提高遠期的膝關節活動度和最終的膝關節功能。【Abstract】 Objective To compare the therapeutic effect of continuous passive motion (CPM) treatment after tibial plateau fractures operation. Methods From June 2008 to June 2009, 86 patients were treated due to closed tibial plateau fractures without combined injuries. The patients were treated with (27 patients, CPM group) and without (59 patients, control group) CPM. The wound healing rates, range of motion and the knee function were compared between the two groups. Results There was no significant difference between the two groups in wound healing rates (P=0.566). Two and six weeks after the operation, there were significant differences between the two groups in flexion degree (Plt;0.001); three and 12 months after the operation, there were no significant differences between the two groups (P=0.219, P=0.512). At the 2nd and 6th week, 3rd and 12th month postoperatively, there were no significant differences between the groups in extension degree. Twelve months after the operation, there were no significant differences between the groups in functional recovery of the knee. Conclusion CPM in the post-operative treatment of tibial plateau fractures is effective increasing knee flexion in the early stage, but is not effective increasing range of motion or knee function in a long term.