Objective To explore the risk factors related to periprosthetic infection after breast augmentation, and to provide a basis for reducing the risk of postoperative infection. Methods A total of 1 056 female patients who underwent breast augmentation between January 2010 and January 2018 were analyzed retrospectively. The patients were 20 to 44 years old (mean, 31.6 years). The body mass index (BMI) was 19.0-31.1 kg/m2, with an average of 24.47 kg/m2. According to the periprosthetic infection standard of the United States Centers for Disease Control and Prevention (CDC), the patients were divided into infection group and non-infection group. Age, BMI, diabetes, previous history of immunosuppression, history of smoking, previous history of breast surgery, previous history of mastitis, combined with active dermatitis, surgical approach, the type and shape of breast prosthesis, implant in the different layers, combined with mastopexy, operation time, postoperative antibiotic time, postoperative breast crash, and postoperative potential infection surgery were analyzed by univariate analysis. The influencing factors of prosthetic infection were screened by logistic regression. Results Periprosthetic infection occurred in 60 cases after operation, and the infection rate was 5.68%. Among them, 11 cases were acute infection, 33 cases were subacute infection, 16 cases were delayed infection, and 20 cases were positive in bacterial culture. Postoperative breast crash occurred in 114 cases. Univariate analysis showed that diabetes, previous history of immunosuppression, history of smoking, previous history of mastitis, postoperative breast crash, postoperative potential infection surgery, and combined with breast suspension were the influencing factors of postoperative periprosthetic infection (P<0.05). Multivariate analysis showed that diabetes, history of smoking, and postoperative breast crash were the risk factors of periprosthetic infection (P<0.05). Conclusion Diabetes, smoking, and postoperative breast crash are the risk factors of periprosthetic infection after breast augmentation.
睡眠呼吸暫停低通氣綜合征( OSAHS) 是一種常見的全身性慢性疾病, 主要表現為呼吸暫停和低通氣, 反復發生低氧血癥、高碳酸血癥和睡眠結構紊亂, 導致白天嗜睡、情緒異常、神經認知功能障礙、心腦血管疾病等。這些異常對患者的日常生活、社會功能、工作效率及認知功能等方面都有不同程度的損害, 使患者生活質量明顯下降。多項研究提示 OSAHS患者生活質量與抑郁、白天嗜睡、社會支持等密切相關, OSAHS 相關的生活質量評估量表不僅能關注多導睡眠圖( PSG) 無法反映的主觀癥狀如嗜睡、困倦等, 而且反映OSAHS 導致的器官功能損害及其嚴重程度。本文主要就用于評價OSAHS患者生活質量主要的相關量表及其應用, 以及目前一些治療措施對生活質量的影響作一綜述。
【Abstract】 Objective To summarize the latest developments in silk fibroin as biomaterials and its appl icationsin tissue engineering. Methods The recent original l iterature on silk fibroin as biomaterials were extensively reviewed,illustrating the properties and appl ications of silk fibroin biomaterials in tissue engineering. Results Silk fibroinas biomaterials had good biocompatibil ity and degradabil ity. It supported the cell adhesion differentiation and growth. It was used for artificial l igament, vessel, bone, nerve and so on. After modification, silk fibroin could be extensively used in tissue engineering. Conclusion Silk fibroin is a good biomaterial, which has a great potential appl ications in tissue engineering.
Objective To summarize the latest developments in silk protein fiber as biomaterials and their applications in tissue engineering. Methods Recent original literature on silk protein fiber as biomaterials were reviewed, illustrating the properties of silk protein fiber biomaterials. Results The silk protein fiber has the same functions of supporting the cell adhesion, differentiation and growth as native collagen, and is renewed as novel biomaterials with good biocompatibility, unique mechanical properties and is degradable over a longer time. Conclusion Silk protein-fiber can be used as asuitable matrix for three dimensional cell culture in tissue engineering. It has a great potential applications in other fields.
Objective To review the appl ication of electrospinning in preparation of tendon tissue engineered scaffolds, to describe its appl ication effect and prospects. Methods Recent l iterature was extensively reviewed and summarized from various aspects, concerning the appl ication of electrospinning in preparing tendon tissue engineered scaffolds. Results Because of its huge surface and high porosity, the electrospun fibers prepared by electrospinning technology have been widely used in the manufacture of tendon tissue engineered scaffolds in recent years. A variety of materials, including polylactic acid, have been successfully electrospun into various types of tendon tissue engineered scaffolds, and goodresults in the repair of tendon defect were achieved. Conclusion The electrospinning technology has provide a new way for the preparation of the tendon tissue engineered scaffolds, with the perfection of the technology they will have broad application prospects in the field of tendon tissue engineering.
Objective To review the research progress of cell-scaffold complex in the tendon tissue engineering. Methods Recent literature concerning cell-scaffold complex in the tendon tissue engineering was reviewed, the research situation of the cell-scaffold complex was elaborated in the aspects of seed cells, scaffolds, cell culture, and application. Results In tendon tissue engineering, a cell-scaffold complex is built by appropriate seed cells and engineered scaffolds. Experiments showed that modified seed cells had better therapeutic effects. Further, scaffold functionality could be improved through surface modification, growth factor cure, mechanical stimulation, and contact guidance. Among these methods, mechanical stimulation revealed the most significant results in promoting cell proliferation and function. Through a variety of defect models, it is demonstrated that the use of cell-scaffold complex could achieve satisfactory results for tendon regeneration. Conclusion The cell-scaffold complex for tendon tissue engineering is a popular research topic. Although it has not yet met the requirement of clinical use, it has broad application prospects.