目的 探討心理行為干預對痛風患者遵醫行為的影響。 方法 2006年1月-2010年9月,選取痛風患者190例,隨機分為干預組和對照組,兩組均進行遵醫行為評價和疾病相關檢查;對干預組進行認知行為干預,分析患者存在的痛風飲食治療的認知誤區,有針對性地進行心理行為干預。 結果 干預后,干預組認知行為總分和各單項分均高于對照組(P<0.05),膽固醇、甘油三酯和體質量指數均低于對照組(P<0.05);干預組19例(20.0%)復發,對照組36例(37.9%)復發,兩組復發率比較,差異有統計學意義(χ2=7.390,P=0.007)。 結論 行為認知治療可提高痛風患者的治療依從性,從而有助于改善尿酸等相關指標。
【摘要】 目的 探討心理干預對糖尿病患者血糖控制及情緒的影響。 方法 2001年3月-2009年7月將120例2型糖尿病患者隨機分成干預組和對照組,每組各60例。兩組均給予正規藥物治療,干預組同時予心理干預。8周后用焦慮自評量表(self-rating anxiety scale,SAS)、抑郁自評量表(self-rating depression scale,SDS)評定兩組患者情緒變化,同時測定空腹血糖、餐后2 h血糖。 結果 干預前后干預組空腹血糖及餐后2 h 血糖下降值多于對照組,差異有統計學意義(Plt;0.05);通過干預,干預組患者SAS、SDS評分均有明顯改善,干預前后評分差異有統計學意義(Plt;0.05),對照組干預前后差異無統計學意義(Pgt;0.05);患者血糖與SAS、SDS評分等因子呈現中等程度的相關性(|r|為0.4~0.6,Plt;0.05)。 結論 糖尿病患者血糖與SAS、SDS等情緒指標相關,心理干預能顯著改善血糖和患者情緒。【Abstract】 Objective To study the effect of psychological intervention on blood-glucose control and emotions of diabetic patients. Methods A total of 120 patients with type 2 diabetes treated between March 2001 and July 2009 were randomly divided into the intervention group and the control group with 60 patients in each. Medicine treatment was carried out for patients in both groups, and psychological intervention was applied only to the intervention group. Eight weeks later, self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were used to evaluate emotion changes of the patients. Fasting blood glucose, post-meal blood glucose (P2hBG) examination were conducted at the same time. Results The result showed a significantly larger decrease of both fasting blood glucose and post-meal blood glucose in the intervention group than the control group (Plt;0.05). Through these methods, the SAS and SDS evaluation of patients in the intervention group improved significantly (Plt;0.05); However, the change of these two scores was not statistically significant in the control group (Pgt;0.05). There was a mid-level correlation between the blood sugar level of diabetic patients and SAS, SDS evaluation scores (0.4lt;|r|lt;0.6, Plt;0.05). Conclusion The blood sugar level of patients with diabetes is closely related to SAS and SDS scores, and psychological intervention can significantly improve the control of blood glucose and emotions of the patients.
目的了解非酒精性脂肪性肝臟疾病(nonalcoholic fatty liver disease,NAFLD)的流行病學情況以及NAFLD的流行病學負擔和經濟負擔,為醫院管理決策提供參考。方法檢索國內外NAFLD相關指南、流行病學調查分析、疾病負擔研究的相關文獻并對其研究進展進行綜述。結果NAFLD在全球發病率逐年上升,NAFLD的疾病負擔逐年增加。由NAFLD導致肝硬化和肝癌的發病率、病死率和傷殘調整壽命年逐年增高。NAFLD相關疾病的住院和門診患者顯著增加,其整體醫療費用也呈現不斷上升的趨勢,可能的原因與健康保健意識、新藥研究、人口老齡化、過度醫療消費有關。另外,兒童及青少年NAFLD患者發生肝臟或肝外疾病的風險明顯升高。結論通過了解NAFLD的流行病學趨勢,對NAFLD的疾病負擔以及影響其治療費用增加的相關因素有了一定的認識,認為進一步關注和加強NAFLD及其相關肝硬化和肝癌的遺傳特征、發病機制、藥物研發、早期診斷等研究是有必要的,同時兒童和青少年 NAFLD群體不容忽視。