去甲腎上腺素治療感染性休克時對肺靜脈血管阻力的影響_《中國呼吸與危重監護雜志》

作者：

索良源 ,  張錦

中國醫科大學盛京醫院麻醉科（遼寧沈陽 110003）;

關鍵詞：

感染性休克去甲腎上腺素肺靜脈血管阻力

視頻：

導出 下載 收藏 掃碼 引用

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

引用本文： 索良源,張錦. 去甲腎上腺素治療感染性休克時對肺靜脈血管阻力的影響. 中國呼吸與危重監護雜志, 2009, 09(3): 303-306. doi: 復制

1.	Liaudet L, Szabo C, Evgenov OV, et al. Flagellin from Gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis. Shock, 2003, 19: 131-137.
2.	Annane D, Vignon P, Renault A, et al. Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet, 2007, 370: 676-684.
3.	Martin C, Viviand X, Leone M, et al. Effect of norepinephrine on the outcome of septic shock. Crit Care Med, 2000, 28: 2758-2765.
4.	De Backer D, Creteur J, Silva E, et al. Effects of dopamine,norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? Crit Care Med, 2003 , 31 : 1659-1667.
5.	Dunser MW, Mayr AJ, Tur A, et al. Ischemic skin lesions as a complication of continuous wasopressin infusion in catecholamineresistant wasodilatory shock: incidence and risk factor. Crit Care Med, 2003, 31: 1394-1398.
6.	Dellinger RP, Levy MM, Carlet JM, et al. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med, 2008, 34: 17-60.
7.	Landry DW, Levin HR, Gallant EM, et al. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation, 1997 ,95: 1122-1125.
8.	林愛華, 郭鳳梅. 血管活性藥物對感染性休克患者動脈血乳酸的影響. 齊齊哈爾醫學院學報, 2005, 26: 888-889.
9.	LauzierF,Lévy B, Lamarre P, et al. Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial.Intensive Care Med, 2006, 32: 1782-1789.
10.	Kellum JA, Decker JM. Use of dopamine in acute renal failure: a meta-analysis. Crit Care Med, 2001, 29: 1526-1531.
11.	Martin C, Viviand X, Arnaud S, et al. Effects of norepinephrine plus dobutamine or norepinephrine alone on left ventricular performance of septic shock patients. Crit Care Med, 1999, 27: 1708-1713.
12.	Muthalif MM, Uddin MR, Fatima S, et al. Small GTP binding protein Ras contributes to norepinephrine-induced mitogenesis of vascular smooth muscle cells. Prostaglandins Other Lipid Mediat, 2001, 65:33-43.
13.	Walch L, Labat C, Gascard JP, et al. Prostanoid receptors involved in the relaxation of human pulmonary vessels. Br J Pharmacol,1999, 126: 859-866.
14.	Vaz-da-Silva MJ, Magina S, Domingues-Costa A, et al. The role of the endocardium in the facilitatory effect of bradykinin on electrically-induced release of noradrenaline in rat cardiac ventricle.Br J Pharmacol, 1996, 118: 364-368.
15.	Cocks TM, Angus JA. Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin. Nature, 1983, 305: 627-630.
16.	Miller VM, Vanhoutte PM. Endothelial alpha 2 -adrenoceptors in canine pulmonary and systemic blood vessels. Eur J Pharmacol,1985, 118: 123-129.
17.	Guimar　S,Moura D. Vascular adrenoceptors: an update. Pharmacol Rev, 2001, 53: 319-356.
18.	Bockman CS, Jeffries WB, Abel PW. Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium. J Pharmacol Exp Ther, 1993, 267: 1126-1133.
19.	Janssen LJ, Lu-Chao H, Netherton S. Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase. Am J Physiol Lung Cell Mol Physiol, 2001 , 280: L666 -L674.
20.	Ding X, Murray PA. Cellular mechanisms of thromboxane A2 -mediated contraction in pulmonary veins. Am J Physiol Lung Cell Mol Physiol, 2005, 289: L825-L833.
21.	Bylund DB, Eikenberg DC, Hieble JP, et al. International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol Rev, 1994 ,46: 121-136.
22.	Blaylock NA, Wilson VG. Pharmacological characterization of noradrenaline-induced contractions of the porcine isolated palmar lateral vein and palmar common digital artery. Br J Pharmacol, 1995, 114: 694-702.
23.	G　rnemann T, von Wenckstern H, Kleuser B, et al. Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins. Br J Pharmacol, 2007, 151: 186-194.
24.	Somlyo AP, Somlyo AV. Signal transduction by G-proteins, rhokinase and protein phosphatase to smoothmuscle and non-muscle myosin. J Physiol, 2000, 522: 177 -185.
25.	Okabe K, Kitamura K, Kuriyam K. Features of 4- aminopyr-idinesensitive outward current observed in single smooth mus-cle cells from the rabbit pulmonary artery. Pflugers Arch,1987, 409: 561-568.
26.	Petitcolin MA, Spitzbarth-Régrigny E, Bueb JL, et al. Role of Giproteins in norepinephrine-mediated vasoconstriction in rat tail artery smooth muscle. Biochem Pharmacol, 2001, 61: 1169-1175.
27.	Atkinson J, Trescases N, Benedek C, et al. Alpha-1 and alpha-2 adrenoceptor agonists induce vasoconstriction of the normotensive rat caudal artery in vitro by stimulation of a heterogeneous population of alpha-1 adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol,1988, 338: 529-535.
28.	Zhong H, Minneman KP. Alpha1 -adrenoceptor subtypes. Eur J Pharmacol, 1999, 375: 261-276.
29.	Hallemeesch MM, Janssen BJ, de Jonge WJ, et al. NO production by cNOS and iNOS reflects blood pressure changes in LPS-challenged mice. Am J Physiol Endocrinol Metab, 2003, 285: E871-E875.
30.	Ding X, Murray PA. Regulation of pulmonary venous tone in response to muscarinic receptor activation. Am J Physiol Lung Cell Mol Physiol, 2005, 288: L131-L140.
31.	段國辰, 凌亦凌, 谷振勇, 等. 八肽膽囊收縮素對家兔內毒素休克時主動脈及肺動脈反應性改變的影響. 中國急救醫學, 2002,22: 693-697.
32.	Schmeck J, Heller A, Gr　schler A, et al. Impact of endothelin-1 in endotoxin-induced pulmonary vascular reactions. Crit Care Med, 2000, 28: 2851-2857.
33.	裴凌, 王俊科, 傅文, 等. 腫瘤壞死因子-α損傷的肺動脈內皮細胞對肺動脈平滑肌細胞增殖的影響及內皮細胞熱應激反應的干擾作用. 中華麻醉學雜志, 2000, 20: 47-50.
34.	Zhang RZ, Yang Q, YimAP, et al. Role of NO and EDHF-mediated endothelial function in the porcine pulmonary circulation:comparison between pulmonary artery and vein. Vascular Pharmacology, 2006, 44: 183-191.
35.	Ding X, Murray PA. Regulation of pulmonary venous tone in response to muscarinic receptor activation. Am J Physiol Lung Cell Mol Physiol, 2005, 288: L131-L140.
36.	Angle MR, Molloy DW, Penner B, et al. The cardiopulmonary and renal hemodynamic effects of norepinephrine in canine pulmonary embolism. Chest, 1989, 95: 1333-1337.
37.	D′Ambra MN, LaRaia PJ, Philbin DM, et al. Prostaglandin E1. A new therapy for refractory right heart failure and pulmonary hypertension after mitral valve replacement. J Thorac Cardiovasc Surg, 1985, 89: 567-572.

1. Liaudet L, Szabo C, Evgenov OV, et al. Flagellin from Gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis. Shock, 2003, 19: 131-137.
2. Annane D, Vignon P, Renault A, et al. Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial. Lancet, 2007, 370: 676-684.
3. Martin C, Viviand X, Leone M, et al. Effect of norepinephrine on the outcome of septic shock. Crit Care Med, 2000, 28: 2758-2765.
4. De Backer D, Creteur J, Silva E, et al. Effects of dopamine,norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? Crit Care Med, 2003 , 31 : 1659-1667.
5. Dunser MW, Mayr AJ, Tur A, et al. Ischemic skin lesions as a complication of continuous wasopressin infusion in catecholamineresistant wasodilatory shock: incidence and risk factor. Crit Care Med, 2003, 31: 1394-1398.
6. Dellinger RP, Levy MM, Carlet JM, et al. Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock: 2008. Intensive Care Med, 2008, 34: 17-60.
7. Landry DW, Levin HR, Gallant EM, et al. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation, 1997 ,95: 1122-1125.
8. 林愛華, 郭鳳梅. 血管活性藥物對感染性休克患者動脈血乳酸的影響. 齊齊哈爾醫學院學報, 2005, 26: 888-889.
9. LauzierF,Lévy B, Lamarre P, et al. Vasopressin or norepinephrine in early hyperdynamic septic shock: a randomized clinical trial.Intensive Care Med, 2006, 32: 1782-1789.
10. Kellum JA, Decker JM. Use of dopamine in acute renal failure: a meta-analysis. Crit Care Med, 2001, 29: 1526-1531.
11. Martin C, Viviand X, Arnaud S, et al. Effects of norepinephrine plus dobutamine or norepinephrine alone on left ventricular performance of septic shock patients. Crit Care Med, 1999, 27: 1708-1713.
12. Muthalif MM, Uddin MR, Fatima S, et al. Small GTP binding protein Ras contributes to norepinephrine-induced mitogenesis of vascular smooth muscle cells. Prostaglandins Other Lipid Mediat, 2001, 65:33-43.
13. Walch L, Labat C, Gascard JP, et al. Prostanoid receptors involved in the relaxation of human pulmonary vessels. Br J Pharmacol,1999, 126: 859-866.
14. Vaz-da-Silva MJ, Magina S, Domingues-Costa A, et al. The role of the endocardium in the facilitatory effect of bradykinin on electrically-induced release of noradrenaline in rat cardiac ventricle.Br J Pharmacol, 1996, 118: 364-368.
15. Cocks TM, Angus JA. Endothelium-dependent relaxation of coronary arteries by noradrenaline and serotonin. Nature, 1983, 305: 627-630.
16. Miller VM, Vanhoutte PM. Endothelial alpha 2 -adrenoceptors in canine pulmonary and systemic blood vessels. Eur J Pharmacol,1985, 118: 123-129.
17. Guimar　S,Moura D. Vascular adrenoceptors: an update. Pharmacol Rev, 2001, 53: 319-356.
18. Bockman CS, Jeffries WB, Abel PW. Binding and functional characterization of alpha-2 adrenergic receptor subtypes on pig vascular endothelium. J Pharmacol Exp Ther, 1993, 267: 1126-1133.
19. Janssen LJ, Lu-Chao H, Netherton S. Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase. Am J Physiol Lung Cell Mol Physiol, 2001 , 280: L666 -L674.
20. Ding X, Murray PA. Cellular mechanisms of thromboxane A2 -mediated contraction in pulmonary veins. Am J Physiol Lung Cell Mol Physiol, 2005, 289: L825-L833.
21. Bylund DB, Eikenberg DC, Hieble JP, et al. International Union of Pharmacology nomenclature of adrenoceptors. Pharmacol Rev, 1994 ,46: 121-136.
22. Blaylock NA, Wilson VG. Pharmacological characterization of noradrenaline-induced contractions of the porcine isolated palmar lateral vein and palmar common digital artery. Br J Pharmacol, 1995, 114: 694-702.
23. G　rnemann T, von Wenckstern H, Kleuser B, et al. Characterization of the postjunctional alpha 2C-adrenoceptor mediating vasoconstriction to UK14304 in porcine pulmonary veins. Br J Pharmacol, 2007, 151: 186-194.
24. Somlyo AP, Somlyo AV. Signal transduction by G-proteins, rhokinase and protein phosphatase to smoothmuscle and non-muscle myosin. J Physiol, 2000, 522: 177 -185.
25. Okabe K, Kitamura K, Kuriyam K. Features of 4- aminopyr-idinesensitive outward current observed in single smooth mus-cle cells from the rabbit pulmonary artery. Pflugers Arch,1987, 409: 561-568.
26. Petitcolin MA, Spitzbarth-Régrigny E, Bueb JL, et al. Role of Giproteins in norepinephrine-mediated vasoconstriction in rat tail artery smooth muscle. Biochem Pharmacol, 2001, 61: 1169-1175.
27. Atkinson J, Trescases N, Benedek C, et al. Alpha-1 and alpha-2 adrenoceptor agonists induce vasoconstriction of the normotensive rat caudal artery in vitro by stimulation of a heterogeneous population of alpha-1 adrenoceptors. Naunyn Schmiedebergs Arch Pharmacol,1988, 338: 529-535.
28. Zhong H, Minneman KP. Alpha1 -adrenoceptor subtypes. Eur J Pharmacol, 1999, 375: 261-276.
29. Hallemeesch MM, Janssen BJ, de Jonge WJ, et al. NO production by cNOS and iNOS reflects blood pressure changes in LPS-challenged mice. Am J Physiol Endocrinol Metab, 2003, 285: E871-E875.
30. Ding X, Murray PA. Regulation of pulmonary venous tone in response to muscarinic receptor activation. Am J Physiol Lung Cell Mol Physiol, 2005, 288: L131-L140.
31. 段國辰, 凌亦凌, 谷振勇, 等. 八肽膽囊收縮素對家兔內毒素休克時主動脈及肺動脈反應性改變的影響. 中國急救醫學, 2002,22: 693-697.
32. Schmeck J, Heller A, Gr　schler A, et al. Impact of endothelin-1 in endotoxin-induced pulmonary vascular reactions. Crit Care Med, 2000, 28: 2851-2857.
33. 裴凌, 王俊科, 傅文, 等. 腫瘤壞死因子-α損傷的肺動脈內皮細胞對肺動脈平滑肌細胞增殖的影響及內皮細胞熱應激反應的干擾作用. 中華麻醉學雜志, 2000, 20: 47-50.
34. Zhang RZ, Yang Q, YimAP, et al. Role of NO and EDHF-mediated endothelial function in the porcine pulmonary circulation:comparison between pulmonary artery and vein. Vascular Pharmacology, 2006, 44: 183-191.
35. Ding X, Murray PA. Regulation of pulmonary venous tone in response to muscarinic receptor activation. Am J Physiol Lung Cell Mol Physiol, 2005, 288: L131-L140.
36. Angle MR, Molloy DW, Penner B, et al. The cardiopulmonary and renal hemodynamic effects of norepinephrine in canine pulmonary embolism. Chest, 1989, 95: 1333-1337.
37. D′Ambra MN, LaRaia PJ, Philbin DM, et al. Prostaglandin E1. A new therapy for refractory right heart failure and pulmonary hypertension after mitral valve replacement. J Thorac Cardiovasc Surg, 1985, 89: 567-572.

上一篇
汶川地震四川省衛生應急救援成效分析
下一篇
汶川地震一線“三甲”醫院志愿者組織管理

《中國呼吸與危重監護雜志》

去甲腎上腺素治療感染性休克時對肺靜脈血管阻力的影響

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

上一篇

下一篇

Format

Content

《中國呼吸與危重監護雜志》

去甲腎上腺素治療感染性休克時對肺靜脈血管阻力的影響

摘要 全文 圖表 視頻 參考文獻 施引文獻 補充材料

上一篇

下一篇

Format

Content

摘要全文圖表視頻參考文獻施引文獻補充材料