心理干預治療癌癥患者抑郁癥的系統評價_《中國循證醫學雜志》

作者：

1. 甘肅省第二人民醫院（蘭州 730000）；2. 蘭州大學第二醫院（蘭州 730000）;

關鍵詞：

心理干預癌癥抑郁癥 Meta 分析

DOI：

10.7507/1672-2531.20100408

視頻：

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目的　系統評價心理干預治療癌癥患者抑郁癥的療效。
方法　計算機檢索Cochrane Library、PubMed、EMbase、中國生物醫學文獻數據庫、中國期刊全文數據庫、維普中文科技期刊數據庫，檢索時間從各數據庫建庫至2009 年10 月；同時手工檢索相關領域的雜志，全面查找符合納入標準的隨機對照試驗（RCT），用RevMan 5.0 軟件進行統計分析。
結果　共納入11 篇RCT，包括1 670 例患者。Meta 分析結果顯示，常規治療和心理干預聯合常規治療在治療癌癥患者抑郁癥得分減少方面差異有統計學意義［SMD= – 0.40，95%CI （– 0.70，– 0.11）］，在治療癌癥患者焦慮癥得分減少方面差異無統計學意義［SMD= – 0.68，95%CI （– 1.37，0.01）］。敏感性分析結果顯示，心理干預聯合常規治療與常規治療癌癥患者焦慮癥得分方面差異有統計學意義［SMD= – 0.30，95%CI （– 0.52，– 0.08）］。
結論　與常規治療相比，心理干預聯合常規治療癌癥患者可明顯改善癌癥患者的精神障礙癥狀，但尚需更多高質量大樣本的隨機對照試驗進一步證實。

引用本文： 姜曉梅,米登海,王宏權,張蘭. 心理干預治療癌癥患者抑郁癥的系統評價. 中國循證醫學雜志, 2010, 10(3): 352-355. doi: 10.7507/1672-2531.20100408 復制

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2.	Pascoe S, Edelman S, Kidman A, et al. Prevalence of psychological distress and use of support service by cancer patient at Sydney hospital. Aust N ZJ Psychiatry, 2000, 34(5): 785-791.
3.	Zabora J, BrintzenhofeSzoc K, Crubow B, et al. The prevalence of psychological distress by cancer site. Psychooncology, 2001, 10(1): 19-28.
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16.	Wu L, Wang S. Psychotherapy improving depression and anxiety of patients treated with chemotherapy combined with radiotherapy. Chinese Journal of Clinical Rehabilitation, 2003, 7(17): 2462-2463.
17.	Laidlaw T, Bennett BM, Dwivedi P, et al. Quality of life and mood changes in metastatic breast cancer after training in self-hypnosis or johrei: a short report. Contemp Hypn, 2005, 22(2): 84-93.
18.	Wilkinson SM, Love SB, Westcombe AM, et al. Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer: a multicenter randomized controlled trial. J Clin Oncol, 2007, 25(5): 532-539.
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20.	Bech P, Cialdella P, Haugh MC, et al. Meta-analysis of randomised controlled trials of fluoxetine versus placebo and tricyclic antidepressants in the short-term treatment of major depression. Br J Psychiatry, 2000, 176 (1): 421-428.
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1. Derogatis LR, Morrow GR, Fetting J, et al. The prevalence of psychiatric disorders among cancer patients. JAMA, 1983, 249(6): 751-757.
2. Pascoe S, Edelman S, Kidman A, et al. Prevalence of psychological distress and use of support service by cancer patient at Sydney hospital. Aust N ZJ Psychiatry, 2000, 34(5): 785-791.
3. Zabora J, BrintzenhofeSzoc K, Crubow B, et al. The prevalence of psychological distress by cancer site. Psychooncology, 2001, 10(1): 19-28.
4. Koenig HG, Gohen HJ, Blazer DG, et al. Brief depression scale for use in the medically ill. Int J Psychiatry Med, 1992, 22(2): 183-195.
5. Okuyama T, Nakane Y, Endo C, et al. Mental health literacy in Japanese cancer patients: ability to recognize depression and preferences of treatments-comparison with Japanese lay public. Psychooncology, 2007, 16(9): 834-842.
6. Zung WW. A self-Rating depression scale. Arch Gen Psychiatry, 1965, 12(1): 63-70.
7. Zung WW. A rating instrument for anxiety disorders. Psychosomatics, 1971, 12(6): 371-379.
8. Higgins JPT, Green S. Cochrane handbook for systematic reviews of interventions version 5.0.1 [updated September 2008]. The Cochrane Collaboration, 2008. Available at: www.cochrane handbook. org.
9. Spiegel D, Bloom JR, Yalom I. Group support for patients with metastatic cancer. A randomized outcome study. Arch Gen Psychiatry, 1981, 38(5): 527-533.
10. Linn MW, Linn BS, Harris R. Effects of counseling for late stage cancer patients. Cancer, 1982, 49(5): 1048-1055.
11. Wood BC, Mynors-Wallis LM. Problem-solving therapy in palliative care. Palliat Med, 1997, 11(1): 49-54.
12. Edelman S, Bell DR, Kidman AD. A group cognitive behaviour therapy programme with metastatic breast cancer patients. Psychooncology, 1999, 8(4): 295-305.
13. Classen C, Butler LD, Koopman C, et al. Supportive-expressive group therapy and distress in patients with metastatic breast cancer: a randomized clinical intervention trial. Arch Gen Psychiatry, 2001, 58(5): 494-501.
14. Goodwin PJ, Leszcz M, Ennis M, et al. The effect of group psychosocial support on survival in metastatic breast cancer. N Engl J Med, 2001, 345(24): 1719-1726.
15. Liossi C, White P. Efficacy of clinical hypnosis in the enhancement of quality of life of terminally ill cancer patients. Contemp Hypn, 2001, 18(3): 145-160.
16. Wu L, Wang S. Psychotherapy improving depression and anxiety of patients treated with chemotherapy combined with radiotherapy. Chinese Journal of Clinical Rehabilitation, 2003, 7(17): 2462-2463.
17. Laidlaw T, Bennett BM, Dwivedi P, et al. Quality of life and mood changes in metastatic breast cancer after training in self-hypnosis or johrei: a short report. Contemp Hypn, 2005, 22(2): 84-93.
18. Wilkinson SM, Love SB, Westcombe AM, et al. Effectiveness of aromatherapy massage in the management of anxiety and depression in patients with cancer: a multicenter randomized controlled trial. J Clin Oncol, 2007, 25(5): 532-539.
19. Pitceathly C, Maguire P, Fletcher I, et al. Can a brief psychological intervention prevent anxiety or depressive disorders in cancer patients? A randomised controlled trial. Ann Oncol, 2009, 20(5): 928-934.
20. Bech P, Cialdella P, Haugh MC, et al. Meta-analysis of randomised controlled trials of fluoxetine versus placebo and tricyclic antidepressants in the short-term treatment of major depression. Br J Psychiatry, 2000, 176 (1): 421-428.
21. Word Health Organization. The world health report 2001. Mental health: new understanding, new hope. [2001-11-01]. http: //www. who. int/whr,.

《中國循證醫學雜志》

心理干預治療癌癥患者抑郁癥的系統評價

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《中國循證醫學雜志》

心理干預治療癌癥患者抑郁癥的系統評價

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