C 臂 CT 引導下微波消融治療非小細胞肺癌的近期療效觀察_Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

Authors：

薛明 ¹ , 李剛 ¹ ,  郭喜田 ¹ , 梁貴友 ² , 王黙 ³

1. ;
2. ;
3. ;

Corresponding?author：

郭喜田, Email: 18660377758@163.com

Keywords：

C 臂 CT; 微波消融; 非小細胞肺癌

DOI：

10.7507/1007-4848.201812027

Video：

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目的探討 C 臂 CT 引導下微波消融治療非小細胞肺癌的安全性及有效性，總結圍術期并發癥的危險因素及處理辦法。方法回顧性分析 2014 年 10 月至 2016 年 10 月我院46例非小細胞肺癌患者在 C 臂 CT 引導下行微波消融治療的臨床資料，其中男 34 例、女 12 例，年齡 71（44～83）歲。分析無進展生存期、總生存期、圍術期并發癥。結果 46 例患者實施了微波消融治療，消融功率 60（45～70）W，消融時間 8（4～15）min。成功率 100.00%，完全消融率 84.91%（45/53），中位隨訪時間為 14（5～24）個月, 1、2 年生存率為 74.31%、28.36%；中位無進展生存期為 13 個月［95%CI（10.42，15.58）］，中位總生存期為 16 個月［95%CI（13.24，18.76）］。并發癥發生率 19.57%（9/46），其中氣胸 8.69%（4/46）；不良反應發生率 43.48%（20/46），其中胸痛 30.43%（14/46），圍術期無嚴重并發癥。結論 C 臂 CT 引導下經皮微波消融治療非小細胞肺癌是一種安全、有效的治療方法，值得推廣。

Citation： 薛明, 李剛, 郭喜田, 梁貴友, 王黙. C 臂 CT 引導下微波消融治療非小細胞肺癌的近期療效觀察. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2019, 26(9): 936-940. doi: 10.7507/1007-4848.201812027 Copy

1.	Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2018, 68(6): 394-424.
2.	Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin, 2016, 66(2): 115-132.
3.	Gobara H, Arai Y, Kobayashi T, et al. Percutaneous radiofrequency ablation for patients with malignant lung tumors: a phase II prospective multicenter study (JIVROSG-0702). Jpn J Radiol, 2016, 34(8): 556-563.
4.	Du S, Qin D, Pang R, et al. Long-term efficacy of radiofrequency ablation combined with chemotherapy in the treatment of patients with advanced non-small Cell Lung Cancer--a retrospective study. Zhongguo Fei Ai Za Zhi, 2017, 20(10): 675-682.
5.	李建軍, 鄭加生, 崔雄偉, 等. CT引導下經皮微波消融治療肺癌的臨床療效分析. 中華介入放射學電子雜志, 2014, 2(1): 35-37.
6.	Sidoff L, Dupuy DE. Clinical experiences with microwave thermal ablation of lung malignancies. Int J Hyperthermia, 2017, 33(1): 25-33.
7.	Belfiore G, Ronza F, Belfiore MP, et al. Patients' survival in lung malignancies treated by microwave ablation: our experience on 56 patients. Eur J Radiol, 2013, 82(1): 177-181.
8.	Healey TT, March BT, Baird G, et al. Microwave ablation for lung neoplasms: a retrospective analysis of long-term results. J Vasc Interv Radiol, 2017, 28(2): 206-211.
9.	Amouyal G, Pernot S, Déan C, et al. Percutaneous radiofrequency ablation of lung metastases from colorectal carcinoma under C-arm cone beam CT guidance. Diagn Interv Imaging, 2017, 98(11): 793-799.
10.	劉寶東, 葉欣, 范衛軍, 等. 影像引導射頻消融治療肺部腫瘤專家共識(2018年版). 中國肺癌雜志, 2018, 21(2): 76-88.
11.	李曉群, 張勇, 黃大鋇, 等. C臂CT在15例肺部小病灶射頻消融術中的應用. 介入放射學雜志, 2013, 22(1): 67-70.
12.	馬勇恩, 馬幸生. CT引導下經皮穿刺微波消融治療原發性肺癌患者39例的臨床分析. 中國胸心血管外科臨床雜志, 2017, 6(23): 488-490.
13.	Kwan SW, Mortell KE, Talenfeld AD, et al. Thermal ablation matches sublobar resection outcomes in older patients with early-stage non-small cell lung cancer. J Vasc Interv Radiol, 2014, 25(1): 1-9.
14.	李記華. C臂CT在胸部介入診療中的應用現狀. 中國介入影像與治療學, 2012, 9(4): 307-310.

1. Bray F, Ferlay J, Soerjomataram I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin, 2018, 68(6): 394-424.
2. Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015. CA Cancer J Clin, 2016, 66(2): 115-132.
3. Gobara H, Arai Y, Kobayashi T, et al. Percutaneous radiofrequency ablation for patients with malignant lung tumors: a phase II prospective multicenter study (JIVROSG-0702). Jpn J Radiol, 2016, 34(8): 556-563.
4. Du S, Qin D, Pang R, et al. Long-term efficacy of radiofrequency ablation combined with chemotherapy in the treatment of patients with advanced non-small Cell Lung Cancer--a retrospective study. Zhongguo Fei Ai Za Zhi, 2017, 20(10): 675-682.
5. 李建軍, 鄭加生, 崔雄偉, 等. CT引導下經皮微波消融治療肺癌的臨床療效分析. 中華介入放射學電子雜志, 2014, 2(1): 35-37.
6. Sidoff L, Dupuy DE. Clinical experiences with microwave thermal ablation of lung malignancies. Int J Hyperthermia, 2017, 33(1): 25-33.
7. Belfiore G, Ronza F, Belfiore MP, et al. Patients' survival in lung malignancies treated by microwave ablation: our experience on 56 patients. Eur J Radiol, 2013, 82(1): 177-181.
8. Healey TT, March BT, Baird G, et al. Microwave ablation for lung neoplasms: a retrospective analysis of long-term results. J Vasc Interv Radiol, 2017, 28(2): 206-211.
9. Amouyal G, Pernot S, Déan C, et al. Percutaneous radiofrequency ablation of lung metastases from colorectal carcinoma under C-arm cone beam CT guidance. Diagn Interv Imaging, 2017, 98(11): 793-799.
10. 劉寶東, 葉欣, 范衛軍, 等. 影像引導射頻消融治療肺部腫瘤專家共識(2018年版). 中國肺癌雜志, 2018, 21(2): 76-88.
11. 李曉群, 張勇, 黃大鋇, 等. C臂CT在15例肺部小病灶射頻消融術中的應用. 介入放射學雜志, 2013, 22(1): 67-70.
12. 馬勇恩, 馬幸生. CT引導下經皮穿刺微波消融治療原發性肺癌患者39例的臨床分析. 中國胸心血管外科臨床雜志, 2017, 6(23): 488-490.
13. Kwan SW, Mortell KE, Talenfeld AD, et al. Thermal ablation matches sublobar resection outcomes in older patients with early-stage non-small cell lung cancer. J Vasc Interv Radiol, 2014, 25(1): 1-9.
14. 李記華. C臂CT在胸部介入診療中的應用現狀. 中國介入影像與治療學, 2012, 9(4): 307-310.

Chinese Journal of Clinical Thoracic and Cardiovascular Surgery

C 臂 CT 引導下微波消融治療非小細胞肺癌的近期療效觀察

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