The Characteristics and Diagnostic Values of MRI for Multiple Sclerosis_West China Medical Journal

Authors：

 HULi-ping

Department of Medical Imaging, Chengdu Tianfu New District People's Hospital, Chengdu, Sichuan 610213, P. R. China;

Corresponding?author：

Keywords：

Multiple sclerosis; Imaging characteristics; Magnetic resonance imaging; Diagnostic values

DOI：

10.7507/1002-0179.20150315

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Objective To investigate the morphology of brain regions undergoing multiple sclerosis (MS) MRI, and furthermore, to investigate possible diagnostic values of MRI for MS. Methods MRI images of 42 MS patients (34 females and 8 males, aged between 35 and 81 years old, averaging at 58) who visited the hospital during the time from December 2007 to December 2013 were collected and analyzed. Routine T1, T2 and fluid attenuated inversion recovery (FLAIR) scans were performed on all the 42 patients. Sagittal T1, T2 and FLAIR scans were performed when necessary. Contrast-enhanced MRI was performed on 9 of the 42 patients. The abnormal findings from MRI scans of all the 42 patients were analyzed. The analysis was further concluded to yield general characteristics of MS patients under MRI. Results A total of 286 lesions were identified in 42 patients. Ninety (31.6%) of the 286 lesions (seen in 35 patients) were found to locate around lateral ventricles; 67 (23.4%) at centrum semiovale (seen in 29 patients); 59 (20.6%) in deep white matter (seen in 28 patients); 46 (16.1%) around corpus callosum (seen in 30 patients); 21 (7.3%) in brain stem, basal ganglia and cerebellar hemispheres (seen in 9 patients); and 3 (1.0%) at cervical spinal cord. In routine MRI images, the lesions showed up as low T1 signal, high T2 signal and high FLAIR signal with the shape of ovoid or round. No mass effect was observed in lesions. In the contrast-enhanced MRI images, the 25 observed lesions showed mild enhancements with the shape of ring, semi-ring and arc. Conclusion Certain characteristic features can be observed in MS MRI images. MRI is an effective diagnostic method for multiple sclerosis diagnosis.

Citation： HULi-ping. The Characteristics and Diagnostic Values of MRI for Multiple Sclerosis. West China Medical Journal, 2015, 30(6): 1101-1104. doi: 10.7507/1002-0179.20150315 Copy

1.	盧德宏, 湯國才. 多發性硬化的臨床病理學[J]. 實用兒科臨床雜志, 2005, 20(4):293-296.
2.	Dineen RA, Vilisaar J, Hlinka J, et al. Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis[J]. Brain, 2009, 132(Pt 1):239-249.
3.	Thornton AE, Raz N, Tucke KA. Memory in multiple sclerosis:contextual encoding deficits[J]. J Int Neuropsychol Soc, 2002, 8(3):395-409.
4.	Calabrese M, Agosta F, Rinaldi F, et al. Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis[J]. Arch Neurol, 2009, 66(9):1144-1150.
5.	李世平, 周毅, 盧蘭香, 等. 多發性硬化認知障礙分析[J]. 河北醫藥, 2014, 36(11):1656-1658.
6.	Mcdonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis:guidelines from the International Panel on the diagnosis of multiple sclerosis[J]. Ann Neurol, 2001, 50(1):121-127.
7.	劉沛武, 吳文澤, 劉四斌. 多發性硬化76例MRI診斷分析[J]. 中國誤診學雜志, 2011, 11(1):179.
8.	趙新湘, 王波, 戴敏方, 等. 多發性硬化MRI表現及其診斷價值[J]. 醫學影像學雜志, 2004, 14(8):620-623.
9.	張麗, 湯春貴, 郝淑彬. 顱腦多發性硬化MRI表現[J]. 中國醫藥導報, 2011, 8(22):96-97, 104.
10.	He J, Grossman RI, Ge Y, et al. Enhancing patterns in multiple sclerosis:evolution and persistence[J]. AJNR Am J Neuroradiol, 2001, 22(4):664-669.
11.	Balashov KE, Aung LL, Dhib-Jalbut S, et al. Acute multiple sclerosis lesion:conversion of restricted diffusion due to vasogenic edema[J]. J Neuroimaging, 2011, 21(2):202-204.
12.	馮逢. 多發性硬化的常見MRI征象分析[J]. 磁共振成像, 2011, 2(4):309-313.
13.	宋峰, 宦怡. MRI在多發性硬化病理機制研究中的應用[J]. 放射學實踐, 2009, 24(12):1383-1385.

1. 盧德宏, 湯國才. 多發性硬化的臨床病理學[J]. 實用兒科臨床雜志, 2005, 20(4):293-296.
2. Dineen RA, Vilisaar J, Hlinka J, et al. Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis[J]. Brain, 2009, 132(Pt 1):239-249.
3. Thornton AE, Raz N, Tucke KA. Memory in multiple sclerosis:contextual encoding deficits[J]. J Int Neuropsychol Soc, 2002, 8(3):395-409.
4. Calabrese M, Agosta F, Rinaldi F, et al. Cortical lesions and atrophy associated with cognitive impairment in relapsing-remitting multiple sclerosis[J]. Arch Neurol, 2009, 66(9):1144-1150.
5. 李世平, 周毅, 盧蘭香, 等. 多發性硬化認知障礙分析[J]. 河北醫藥, 2014, 36(11):1656-1658.
6. Mcdonald WI, Compston A, Edan G, et al. Recommended diagnostic criteria for multiple sclerosis:guidelines from the International Panel on the diagnosis of multiple sclerosis[J]. Ann Neurol, 2001, 50(1):121-127.
7. 劉沛武, 吳文澤, 劉四斌. 多發性硬化76例MRI診斷分析[J]. 中國誤診學雜志, 2011, 11(1):179.
8. 趙新湘, 王波, 戴敏方, 等. 多發性硬化MRI表現及其診斷價值[J]. 醫學影像學雜志, 2004, 14(8):620-623.
9. 張麗, 湯春貴, 郝淑彬. 顱腦多發性硬化MRI表現[J]. 中國醫藥導報, 2011, 8(22):96-97, 104.
10. He J, Grossman RI, Ge Y, et al. Enhancing patterns in multiple sclerosis:evolution and persistence[J]. AJNR Am J Neuroradiol, 2001, 22(4):664-669.
11. Balashov KE, Aung LL, Dhib-Jalbut S, et al. Acute multiple sclerosis lesion:conversion of restricted diffusion due to vasogenic edema[J]. J Neuroimaging, 2011, 21(2):202-204.
12. 馮逢. 多發性硬化的常見MRI征象分析[J]. 磁共振成像, 2011, 2(4):309-313.
13. 宋峰, 宦怡. MRI在多發性硬化病理機制研究中的應用[J]. 放射學實踐, 2009, 24(12):1383-1385.

West China Medical Journal

The Characteristics and Diagnostic Values of MRI for Multiple Sclerosis

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