雙相障礙患者生活質量研究現狀及展望_West China Medical Journal

Authors：

 肖霖 , 林小玲 , 王慶妍 ,  唐四元

中南大學護理學院社區護理學系（長沙，410013）;

Corresponding?author：

唐四元, Email: tangsyuan@126.com

Keywords：

雙相障礙; 生活質量; 現狀分析; 展望

DOI：

10.7507/1002-0179.20140725

Video：

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隨著醫學模式的轉變，生活質量評估逐漸成為精神疾病臨床療效的一個主要指標，日益受到精神醫學界的關注。但目前在這一領域的研究仍相對匱乏，國內更加滯后。現對雙相障礙患者生活質量研究現狀進行綜述，就其存在的問題及下一步研究提出建議，以期讓生活質量評估能更好地用于指導臨床治療和促進患者的全面康復。

Citation： 肖霖, 林小玲, 王慶妍, 唐四元. 雙相障礙患者生活質量研究現狀及展望. West China Medical Journal, 2014, 29(12): 2397-2400. doi: 10.7507/1002-0179.20140725 Copy

1.	楊春強. 雙向情感障礙的最新研究進展[J]. 精神醫學雜志, 2007, 20(6):408-410.
2.	Sanchez-Moreno J, Martinez-Aran A, Tabares-Seisdedos R, et al. Functioning and disability in bipolar disorder:an extensive review[J]. Psychother Psychosom, 2009, 78(5):285-297.
3.	Eissa MF, ElGhoniemy S, Hamed D, et al. The quality of life in patients with bipolar disorder who have achieved remission in an Egyptian sample[J]. Middle East Curr Psychiatry, 2012, 19:222-231.
4.	Dean BB, Germer D, Gerner RH. A systematic review evaluating health-related quality of life, work impairment, and healthcare costs and utilization in bipolar disorder[J]. Curr Med Res Opin, 2004, 20(2):139-154.
5.	Namjoshi MA, Buesching DP. A review of the health-related quality of Life literature in bipolar disorder[J]. Qual Life Res, 2001, 10(2):105-115.
6.	Revicki DA, Matza LS, Flood E, et al. Bipolar disorder and health-related quality of life:review of burden of disease and clinical trials[J]. Pharmacoeconomics, 2005, 23(6):583-594.
7.	Michalak EE, Yatham LN, Lam RW. Quality of life in bipolar disorder:a review of the literature[J]. Health Qual Life Out, 2005, 3:72.
8.	Dias W, Brissos S, Frey BN, et al. Insight, quality of life and cognitive functioning in euthymic patients with bipolar disorder[J]. J Affect Disord, 2008, 110(1/2):75-83.
9.	Michalak EE, Yatham LN, Kolesar S, et al. Bipolar disorder and quality of life:a patient-centered perspective[J]. Qual Life Res, 2006, 15(1):25-37.
10.	Leidy NK, Palmer C, Murray M, et al. Health-related quality of life assessment in euthymic and depressed patients with bipolar disorder:psychometric performance of four self-report measures[J]. J Affect Disord, 1998, 48(2/3):207-214.
11.	Yatham LN, Lecrubier Y, Fieve RR, et al. Quality of life in patients with bipolar Ⅰ depression:data from 920 patients[J]. Bipolar Disord, 2004, 6(5):379-385.
12.	Xiang YT, Li LJ, Zhou JJ, et al. Quality of life of patients with euthymic bipolar disorder and its associations with demographic and clinical characteristics, psychopathology, and cognitive deficits[J]. Perspect Psychiatr Care, 2014, 50(1):44-50.
13.	Rosa AR, Reinares M, Franco C, et al. Clinical predictors of functional outcome of bipolar patients in remission[J]. Bipolar Disord, 2009, 11(4):401-409.
14.	Ishak WW, Brown K, Aye SS, et al. Health-related quality of life in bipolar disorder[J]. Bipolar Disord, 2012, 14(1):6-18.
15.	鄭尤民, 張程赪. 心理干預對雙相障礙患者認知功能影響的對照研究[J]. 中國民康醫學, 2010, 22(17):2272-2273, 2275.
16.	Goodwin FK, Jamison KR. Manic-depressive illness[M]. New York:Oxford University Press, 1990:102.
17.	Scott J, Paykel E, Morriss R, et al. Cognitive-behavioural therapy for severe and recurrent bipolar disorders:randomised controlled trial[J]. Br J Psychiatry, 2006, 188:313-320.
18.	Bauer M, Glenn T, Grof P, et al. Self-reported data from patients with bipolar disorder:frequency of brief depression[J]. J Affect Disord, 2007, 101(1/2/3):227-233.
19.	Michalak EE, Murray G, Young AH, et al. Burden of bipolar depression:impact of disorder and medications on quality of life[J]. CNS Drugs, 2008, 22(5):389-406.
20.	Hansson L. Determinants of quality of life in people with severe mental illness[J]. Acta Psychiatr Scand, 2006, 113(429):46-50.
21.	Depp CA, Davis CE, Mittal D, et al. Health-related quality of life and functioning of middle-aged and elderly adults with bipolar disorder[J]. J Clin Psychiatry, 2006, 67(2):215-221.
22.	Zhang H, Wisniewski SR, Bauer MS, et al. Comparisons of perceived quality of life across clinical states in bipolar disorder:data from the first 2000 Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) participants[J]. Compr Psychiatry, 2006, 47(3):161-168.
23.	Gutiérrez-Rojas L, Gurpegui M, Ayuso-Mateos JL, et al. Quality of life in bipolar disorder patients:a comparison with a general population sample[J]. Bipolar Disord, 2008, 10(5):625-634.
24.	Gazalle FK, Andreazza AC, Ceresér KM, et al. Clinical impact of late diagnose of bipolar disorder[J]. J Affect Disord, 2005, 86(2/3):313-316.
25.	Saarni SI, Vierti? S, Per?l? J, et al. Quality of life of people with schizophrenia, bipolar disorder and other psychotic disorders[J]. Br J Psychiatry, 2010, 197(5):386-394.
26.	Maina G, Albert U, Bellodi L, et al. Health-related quality of life in euthymic bipolar disorder patients:differences between bipolar Ⅰ and Ⅱ subtypes[J]. J Clin Psychiatry, 2007, 68(2):207-212.
27.	Judd LL, Akiskal HS, Schettler PJ, et al. Psychosocial disability in the course of bipolar Ⅰ and Ⅱ disorders:a prospective, comparative, longitudinal study[J]. Arch Gen Psychiatry, 2005, 62(12):1322-1330.
28.	Chengappa KN, Hennen J, Baldessarini RJ, et al. Recovery and functional outcomes following olanzapine treatment for bipolar Ⅰmania[J]. Bipolar Disord, 2005, 7(1):68-76.
29.	Fagiolini A, Kupfer DJ, Masalehdan A, et al. Functional impairment in the remission phase of bipolar disorder[J]. Bipolar Disord, 2005, 7(3):281-285.
30.	Altshuler LL, Post RM, Black DO, et al. Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder:results of a large, multisite study[J]. J Clin Psychiatry, 2006, 67(10):1551-1560.
31.	Bonnín CM, Sánchez-Moreno J, Martínez-Arán A, et al. Subthreshold symptoms in bipolar disorder:impact on neurocognition, quality of life and disability[J]. J Affect Disord, 2012, 136(3):650-659.
32.	Sentissi O, Navarro JC, De Oliveira H, et al. Bipolar disorders and quality of life:the impact of attention deficit/hyperactivity disorder and substance abuse in euthymic patients[J]. Psychiatry Res, 2008, 161(1):36-42.
33.	Martinez-Aran A, Vieta E, Torrent C, et al. Functional outcome in bipolar disorder:the role of clinical and cognitive factors[J]. Bipolar Disord, 2007, 9(1/2):103-113.
34.	Brissos S, Dias VV, Kapczinski F. Cognitive performance and quality of life in bipolar disorder[J]. Can J Psychiatry, 2008, 53(8):517-524.
35.	Jaeger J, Berns S, Loftus S, et al. Neurocognitive test performance predicts functional recovery from acute exacerbation leading to hospitalization in bipolar disorder[J]. Bipolar Disord, 2007, 9(1/2):93-102.
36.	Wingo AP, Harvey PD, Baldessarini RJ. Neurocognitive impairment in bipolar disorder patients:functional implications[J]. Bipolar Disord, 2009, 11(2):113-125.
37.	Maria Sanchez-Morla E, Barabash A, Martinez-Vizcaino V, et al. Comparative study of neurocognitive function in euthymic bipolar patients and stabilized schizophrenic patients[J]. Psychiatry Res, 2009, 169(3):220-228.
38.	Lecardeur L, Stip E, Giguere M, et al. Effects of cognitive remediation therapies on psychotic symptoms and cognitive complaints in patients with schizophrenia and related disorders:a randomized study[J]. Schizophr Res, 2009, 111(1/2/3):153-158.
39.	Pavuluri MN, West A, Hill SK, et al. Neurocognitive function in pediatric bipolar disorder:3-year follow-up shows cognitive development lagging behind healthy youths[J]. J Am Acad Child Adolesc Psychiatry, 2009, 48(3):299-307.
40.	Brissos S, Dias VV, Carita AI, et al. Quality of life in bipolar typeⅠdisorder and schizophrenia in remission:clinical and neurocognitive correlates[J]. Psychiatry Res, 2008, 160(1):55-62.
41.	Xiang YT, Chiu HF, Ungvari GS. Quality of life and mental health in Chinese culture[J]. Curr Opin Psychiatry, 2010, 23(1):43-47.
42.	Xiang YT, Weng YZ, Leung CM, et al. Subjective quality of life in outpatients with schizophrenia in Hong Kong and Beijing:relationship to socio-demographic and clinical factors[J]. Qual Life Res, 2008, 17(1):27-36.
43.	Hays RD, Hahn H, Marshall G. Use of the SF-36 and other health-related quality of Life measures to assess persons with disabilities[J]. Arch Phys Med Rehabil, 2002, 83(12, 2):S4-S9.
44.	Hays RD, Revicki D, Coyne KS. Application of structural equation modeling to health outcomes research[J]. Eval Health Prof, 2005, 28(3):295-309.
45.	Ritsner MS, Awad AG. Quality of life impairment in schizophrenia, mood and anxiety disorders[M]. New York:Springer, 2007:96.
46.	Merikangas KR, Jin R, He JP, et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative[J]. Arch Gen Psychiatry, 2011, 68(3):241-251.
47.	Goldstein BI. Pediatric bipolar disorder:more than a temper problem[J]. Pediatrics, 2010, 125(6):1283-1285.
48.	Goldstein BI, Birmaher B, Axelson DA, et al. Preliminary findings regarding overweight and obesity in pediatric bipolar disorder[J]. J Clin Psychiatry, 2008, 69(12):1953-1959.
49.	謝雅芳, 黃珠晶, 黃燕春. 護理干預對雙相障礙患者生活質量的影響[J]. 福建醫藥雜志, 2012, 34(4):174-175.
50.	Ayuso-Mateos JL, Nieto-Moreno M, Sánchez-Moreno J, et al. The International Classification of Functioning, Disability and Health:applicability and usefulness in clinical practice[J]. Med Clin (Barc), 2006, 126(12):461-466.
51.	Latalova K, Prasko J, Diveky T, et al. Quality of life in patients with bipolar disorder:a comparison with schizophrenic patients and healthy controls[J]. Psychiatr Danub, 2011, 23(1):21-26.

1. 楊春強. 雙向情感障礙的最新研究進展[J]. 精神醫學雜志, 2007, 20(6):408-410.
2. Sanchez-Moreno J, Martinez-Aran A, Tabares-Seisdedos R, et al. Functioning and disability in bipolar disorder:an extensive review[J]. Psychother Psychosom, 2009, 78(5):285-297.
3. Eissa MF, ElGhoniemy S, Hamed D, et al. The quality of life in patients with bipolar disorder who have achieved remission in an Egyptian sample[J]. Middle East Curr Psychiatry, 2012, 19:222-231.
4. Dean BB, Germer D, Gerner RH. A systematic review evaluating health-related quality of life, work impairment, and healthcare costs and utilization in bipolar disorder[J]. Curr Med Res Opin, 2004, 20(2):139-154.
5. Namjoshi MA, Buesching DP. A review of the health-related quality of Life literature in bipolar disorder[J]. Qual Life Res, 2001, 10(2):105-115.
6. Revicki DA, Matza LS, Flood E, et al. Bipolar disorder and health-related quality of life:review of burden of disease and clinical trials[J]. Pharmacoeconomics, 2005, 23(6):583-594.
7. Michalak EE, Yatham LN, Lam RW. Quality of life in bipolar disorder:a review of the literature[J]. Health Qual Life Out, 2005, 3:72.
8. Dias W, Brissos S, Frey BN, et al. Insight, quality of life and cognitive functioning in euthymic patients with bipolar disorder[J]. J Affect Disord, 2008, 110(1/2):75-83.
9. Michalak EE, Yatham LN, Kolesar S, et al. Bipolar disorder and quality of life:a patient-centered perspective[J]. Qual Life Res, 2006, 15(1):25-37.
10. Leidy NK, Palmer C, Murray M, et al. Health-related quality of life assessment in euthymic and depressed patients with bipolar disorder:psychometric performance of four self-report measures[J]. J Affect Disord, 1998, 48(2/3):207-214.
11. Yatham LN, Lecrubier Y, Fieve RR, et al. Quality of life in patients with bipolar Ⅰ depression:data from 920 patients[J]. Bipolar Disord, 2004, 6(5):379-385.
12. Xiang YT, Li LJ, Zhou JJ, et al. Quality of life of patients with euthymic bipolar disorder and its associations with demographic and clinical characteristics, psychopathology, and cognitive deficits[J]. Perspect Psychiatr Care, 2014, 50(1):44-50.
13. Rosa AR, Reinares M, Franco C, et al. Clinical predictors of functional outcome of bipolar patients in remission[J]. Bipolar Disord, 2009, 11(4):401-409.
14. Ishak WW, Brown K, Aye SS, et al. Health-related quality of life in bipolar disorder[J]. Bipolar Disord, 2012, 14(1):6-18.
15. 鄭尤民, 張程赪. 心理干預對雙相障礙患者認知功能影響的對照研究[J]. 中國民康醫學, 2010, 22(17):2272-2273, 2275.
16. Goodwin FK, Jamison KR. Manic-depressive illness[M]. New York:Oxford University Press, 1990:102.
17. Scott J, Paykel E, Morriss R, et al. Cognitive-behavioural therapy for severe and recurrent bipolar disorders:randomised controlled trial[J]. Br J Psychiatry, 2006, 188:313-320.
18. Bauer M, Glenn T, Grof P, et al. Self-reported data from patients with bipolar disorder:frequency of brief depression[J]. J Affect Disord, 2007, 101(1/2/3):227-233.
19. Michalak EE, Murray G, Young AH, et al. Burden of bipolar depression:impact of disorder and medications on quality of life[J]. CNS Drugs, 2008, 22(5):389-406.
20. Hansson L. Determinants of quality of life in people with severe mental illness[J]. Acta Psychiatr Scand, 2006, 113(429):46-50.
21. Depp CA, Davis CE, Mittal D, et al. Health-related quality of life and functioning of middle-aged and elderly adults with bipolar disorder[J]. J Clin Psychiatry, 2006, 67(2):215-221.
22. Zhang H, Wisniewski SR, Bauer MS, et al. Comparisons of perceived quality of life across clinical states in bipolar disorder:data from the first 2000 Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) participants[J]. Compr Psychiatry, 2006, 47(3):161-168.
23. Gutiérrez-Rojas L, Gurpegui M, Ayuso-Mateos JL, et al. Quality of life in bipolar disorder patients:a comparison with a general population sample[J]. Bipolar Disord, 2008, 10(5):625-634.
24. Gazalle FK, Andreazza AC, Ceresér KM, et al. Clinical impact of late diagnose of bipolar disorder[J]. J Affect Disord, 2005, 86(2/3):313-316.
25. Saarni SI, Vierti? S, Per?l? J, et al. Quality of life of people with schizophrenia, bipolar disorder and other psychotic disorders[J]. Br J Psychiatry, 2010, 197(5):386-394.
26. Maina G, Albert U, Bellodi L, et al. Health-related quality of life in euthymic bipolar disorder patients:differences between bipolar Ⅰ and Ⅱ subtypes[J]. J Clin Psychiatry, 2007, 68(2):207-212.
27. Judd LL, Akiskal HS, Schettler PJ, et al. Psychosocial disability in the course of bipolar Ⅰ and Ⅱ disorders:a prospective, comparative, longitudinal study[J]. Arch Gen Psychiatry, 2005, 62(12):1322-1330.
28. Chengappa KN, Hennen J, Baldessarini RJ, et al. Recovery and functional outcomes following olanzapine treatment for bipolar Ⅰmania[J]. Bipolar Disord, 2005, 7(1):68-76.
29. Fagiolini A, Kupfer DJ, Masalehdan A, et al. Functional impairment in the remission phase of bipolar disorder[J]. Bipolar Disord, 2005, 7(3):281-285.
30. Altshuler LL, Post RM, Black DO, et al. Subsyndromal depressive symptoms are associated with functional impairment in patients with bipolar disorder:results of a large, multisite study[J]. J Clin Psychiatry, 2006, 67(10):1551-1560.
31. Bonnín CM, Sánchez-Moreno J, Martínez-Arán A, et al. Subthreshold symptoms in bipolar disorder:impact on neurocognition, quality of life and disability[J]. J Affect Disord, 2012, 136(3):650-659.
32. Sentissi O, Navarro JC, De Oliveira H, et al. Bipolar disorders and quality of life:the impact of attention deficit/hyperactivity disorder and substance abuse in euthymic patients[J]. Psychiatry Res, 2008, 161(1):36-42.
33. Martinez-Aran A, Vieta E, Torrent C, et al. Functional outcome in bipolar disorder:the role of clinical and cognitive factors[J]. Bipolar Disord, 2007, 9(1/2):103-113.
34. Brissos S, Dias VV, Kapczinski F. Cognitive performance and quality of life in bipolar disorder[J]. Can J Psychiatry, 2008, 53(8):517-524.
35. Jaeger J, Berns S, Loftus S, et al. Neurocognitive test performance predicts functional recovery from acute exacerbation leading to hospitalization in bipolar disorder[J]. Bipolar Disord, 2007, 9(1/2):93-102.
36. Wingo AP, Harvey PD, Baldessarini RJ. Neurocognitive impairment in bipolar disorder patients:functional implications[J]. Bipolar Disord, 2009, 11(2):113-125.
37. Maria Sanchez-Morla E, Barabash A, Martinez-Vizcaino V, et al. Comparative study of neurocognitive function in euthymic bipolar patients and stabilized schizophrenic patients[J]. Psychiatry Res, 2009, 169(3):220-228.
38. Lecardeur L, Stip E, Giguere M, et al. Effects of cognitive remediation therapies on psychotic symptoms and cognitive complaints in patients with schizophrenia and related disorders:a randomized study[J]. Schizophr Res, 2009, 111(1/2/3):153-158.
39. Pavuluri MN, West A, Hill SK, et al. Neurocognitive function in pediatric bipolar disorder:3-year follow-up shows cognitive development lagging behind healthy youths[J]. J Am Acad Child Adolesc Psychiatry, 2009, 48(3):299-307.
40. Brissos S, Dias VV, Carita AI, et al. Quality of life in bipolar typeⅠdisorder and schizophrenia in remission:clinical and neurocognitive correlates[J]. Psychiatry Res, 2008, 160(1):55-62.
41. Xiang YT, Chiu HF, Ungvari GS. Quality of life and mental health in Chinese culture[J]. Curr Opin Psychiatry, 2010, 23(1):43-47.
42. Xiang YT, Weng YZ, Leung CM, et al. Subjective quality of life in outpatients with schizophrenia in Hong Kong and Beijing:relationship to socio-demographic and clinical factors[J]. Qual Life Res, 2008, 17(1):27-36.
43. Hays RD, Hahn H, Marshall G. Use of the SF-36 and other health-related quality of Life measures to assess persons with disabilities[J]. Arch Phys Med Rehabil, 2002, 83(12, 2):S4-S9.
44. Hays RD, Revicki D, Coyne KS. Application of structural equation modeling to health outcomes research[J]. Eval Health Prof, 2005, 28(3):295-309.
45. Ritsner MS, Awad AG. Quality of life impairment in schizophrenia, mood and anxiety disorders[M]. New York:Springer, 2007:96.
46. Merikangas KR, Jin R, He JP, et al. Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative[J]. Arch Gen Psychiatry, 2011, 68(3):241-251.
47. Goldstein BI. Pediatric bipolar disorder:more than a temper problem[J]. Pediatrics, 2010, 125(6):1283-1285.
48. Goldstein BI, Birmaher B, Axelson DA, et al. Preliminary findings regarding overweight and obesity in pediatric bipolar disorder[J]. J Clin Psychiatry, 2008, 69(12):1953-1959.
49. 謝雅芳, 黃珠晶, 黃燕春. 護理干預對雙相障礙患者生活質量的影響[J]. 福建醫藥雜志, 2012, 34(4):174-175.
50. Ayuso-Mateos JL, Nieto-Moreno M, Sánchez-Moreno J, et al. The International Classification of Functioning, Disability and Health:applicability and usefulness in clinical practice[J]. Med Clin (Barc), 2006, 126(12):461-466.
51. Latalova K, Prasko J, Diveky T, et al. Quality of life in patients with bipolar disorder:a comparison with schizophrenic patients and healthy controls[J]. Psychiatr Danub, 2011, 23(1):21-26.

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雙相障礙患者生活質量研究現狀及展望

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