The Role of Nutritional Support in Adjuvant Therapy for Respiratory Failure_West China Medical Journal

Authors：

 YANYi , CHENNa , ZHANGEr-dong

Department of Nutrition, Teaching Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan 610072, P. R. China;

Corresponding?author：

Keywords：

Respiratory failure; Nutritional support; Adjuvant therapy; Therapeutic effect

DOI：

10.7507/1002-0179.20140462

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Objective To explore the role of nutritional support in adjuvant therapy for respiratory failure. Methods We took 72 patients with respiratory failure who were treated in our hospital from August 2011 to January 2013 as the research objects. They were divided into two groups:control group and trial group, with 36 patients in each group. The division of the groups was in accordance with the state food and drug administration clinical trial institution ethics committee standard operating procedures. In the control group, 36 patients were provided with regular treatments according to their condition, like maintaining the respiratory tract unobstructed, oxygen therapy, mechanical ventilation and anti-infection. In the trial group, we offered nutritional support in addition to the normal treatment. Consecutive 20 days was a course of treatment. After four courses, we inspected and put down two groups' respective clinical features, and made a contrast of their treatment conditions. We analyzed the treatments through observational indexes including assessment of eutrophication, treatment efficiency, pulmonary function and arterial blood gases. Results Both groups had obvious therapeutic effects. The observational indexes in the trial group were better than those in the control group. The total effective rate was 91.7% in the trail group after treatment, significantly higher than that in the control group (66.7%) (χ²=8.692, P=0.003); the lung capacity, the ventilation flow ratio and arterial blood gas analysis values in the trial group was better than those in the control group. Conclusion The effect of the nutritional support for the respiratory failure treatment is much better than the regular treatment. The total effective rate is improved while the death rate is lower than before and the patients recover quickly.

Citation： YANYi, CHENNa, ZHANGEr-dong. The Role of Nutritional Support in Adjuvant Therapy for Respiratory Failure. West China Medical Journal, 2014, 29(8): 1508-1511. doi: 10.7507/1002-0179.20140462 Copy

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10.	陳燕, 李鴻霞, 拓寬前. 歐洲營養不良風險調查方法在COPD穩定期患者中的應用研究[J]. 新疆中醫藥, 2011, 29(6):3-4.
11.	楊倩, 張桂, 趙蓓蕾. 1例重度營養不良并發慢性呼吸衰竭患者的營養支持[J]. 醫學研究生學報, 2011, 24(8):895-896.
12.	王建茹, 王越茹. 慢性肺源性心臟病合并呼吸衰竭的營養支持治療[J]. 現代中西醫結合雜志, 2013, 22(5):469-470, 553.
13.	劉新茹, 李立群, 劉颯. COPD合并呼吸衰竭應用無創通氣時營養支持[J]. 臨床肺科雜志, 2012, 17(6):1129-1137.
14.	王海英, 李玲玲. 不同營養支持治療方式對呼吸衰竭患者臨床療效觀察[J]. 廣州醫藥, 2012, 43(3):18-20.
15.	烏日娜, 楊敬平. 機械通氣患者營養支持應用探討[J]. 臨床肺科雜志, 2009, 14(11):1486-1487.
16.	閆文翠, 張雅芬, 馬秀芬, 等. 營養支持治療對老年COPD合并呼吸衰竭患者的影響[J]. 中國老年學雜志, 2013, 33(18):4436-4437.
17.	薛森海, 趙長海, 孫麗娟. 1例重癥甲型H1N1流感并發呼吸衰竭病人的營養支持[J]. 腸外與腸內營養, 2011, 18(1):42-45.
18.	徐麗丹, 賴小燕. 靜脈營養支持療法治療COPD合并呼吸衰竭70例療效分析[J]. 臨床肺科雜志, 2010, 15(5):667-668.

1. 楊省振. 營養支持治療慢性阻塞肺病并Ⅱ型呼吸衰竭療效觀察[J]. 臨床心身疾病雜志, 2008, 14(4):365-365.
2. 陸再英, 鐘南山. 內科學[M]. 7版. 北京:人民衛生出版社, 2008:109-114.
3. 熊寧寧, 劉芳, 蔣萌, 等. 臨床試驗機構倫理委員會標準操作規程[J]. 中國臨床藥理學與治療學, 2003, 8(4):477-480.
4. 袁健紅. 營養支持治療慢性阻塞性肺病并Ⅱ型呼吸衰竭的臨床療效分析[J]. 中國醫藥指南, 2012, 10(35):541-542.
5. 杜嶺先. 慢性阻塞性肺疾病合并呼吸衰竭的臨床治療與分析[J]. 中國醫藥指南, 2013, 11(19):557-557, 558.
6. 王傳湄, 徐麗丹, 賴小燕. 營養支持治療對COPD合并呼吸衰竭的影響[J]. 臨床肺科雜志, 2009, 14(12):1591-1592.
7. Colombo S, Zangrillo A. Invasive and non-invasive ventilation in the treatment of acute respiratory failure[J]. G Ital Cardiol (Rome), 2010, 11(1):12-19.
8. 呂紅, 黃建安. AECOPD合并呼吸衰竭營養支持治療的臨床觀察[J]. 臨床肺科雜志, 2013, 18(4):610-611.
9. 張愛華. 呼吸衰竭患者無創通氣治療的效果觀察[J]. 中國醫藥指南, 2013, 11(34):94-95.
10. 陳燕, 李鴻霞, 拓寬前. 歐洲營養不良風險調查方法在COPD穩定期患者中的應用研究[J]. 新疆中醫藥, 2011, 29(6):3-4.
11. 楊倩, 張桂, 趙蓓蕾. 1例重度營養不良并發慢性呼吸衰竭患者的營養支持[J]. 醫學研究生學報, 2011, 24(8):895-896.
12. 王建茹, 王越茹. 慢性肺源性心臟病合并呼吸衰竭的營養支持治療[J]. 現代中西醫結合雜志, 2013, 22(5):469-470, 553.
13. 劉新茹, 李立群, 劉颯. COPD合并呼吸衰竭應用無創通氣時營養支持[J]. 臨床肺科雜志, 2012, 17(6):1129-1137.
14. 王海英, 李玲玲. 不同營養支持治療方式對呼吸衰竭患者臨床療效觀察[J]. 廣州醫藥, 2012, 43(3):18-20.
15. 烏日娜, 楊敬平. 機械通氣患者營養支持應用探討[J]. 臨床肺科雜志, 2009, 14(11):1486-1487.
16. 閆文翠, 張雅芬, 馬秀芬, 等. 營養支持治療對老年COPD合并呼吸衰竭患者的影響[J]. 中國老年學雜志, 2013, 33(18):4436-4437.
17. 薛森海, 趙長海, 孫麗娟. 1例重癥甲型H1N1流感并發呼吸衰竭病人的營養支持[J]. 腸外與腸內營養, 2011, 18(1):42-45.
18. 徐麗丹, 賴小燕. 靜脈營養支持療法治療COPD合并呼吸衰竭70例療效分析[J]. 臨床肺科雜志, 2010, 15(5):667-668.

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West China Medical Journal

The Role of Nutritional Support in Adjuvant Therapy for Respiratory Failure

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