Clinical Effects of Different Concentrations of Ropivacaine Mesylate on Stellate Ganglion Block_West China Medical Journal

Authors：

 YANGFan , JIANGPeng-fei

Department of Anesthesiology, Suining Central Hospital, Suining, Sichuan 629000, P. R. China;

Corresponding?author：

Keywords：

Ropivacaine mesylate; Stellate ganglion; Nerve block

DOI：

10.7507/1002-0179.20140383

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Objective To compare the functioning time, duration, cervical vascular blood flow and adverse effects of different concentrations of ropivacaine mesylate in performing stellate ganglion block (SGB) under Doppler ultrasound. Methods A total of 240 patients (grade Ⅰ or Ⅱ classified by American Society of Anesthesiologists) aged between 23 and 62 years old ready to undergo SGB between January and April 2013 were chosen for our research. They were randomly divided into two groups with 120 patients in each. Group A and B received unilateral SGB with 7 mL of 0.239% and 0.596% ropivacaine mesylate respectively. Successful SGB was verified by Horner syndrome. The functioning time, duration, hemodynamic changes, cervical vascular blood flow and adverse effects were recorded and compared. Results Horner syndrome was observed in all patients. There was no significant difference in functioning time between the two groups (P>0.05). The duration of functioning was significantly longer in group B than that in group A (P<0.05). No significant difference was found in hemodynamic changes after SGB (P>0.05). No adverse effects were found in both groups. The blood flow of the vertebral artery and the internal carotid artery before the injection and 10 minutes after the injection were not significantly diferent (P>0.05). Conclusion SGB can be induced with 0.239% and 0.596% ropivacaine mesylate. We suggest using 0.596% ropivacaine mesylate by ultrasound-guiding because of the significantly longer functioning duration.

Citation： YANGFan, JIANGPeng-fei. Clinical Effects of Different Concentrations of Ropivacaine Mesylate on Stellate Ganglion Block. West China Medical Journal, 2014, 29(7): 1248-1251. doi: 10.7507/1002-0179.20140383 Copy

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22.	Feigl GC, Rosmarin W, Stelzl A, et al. Comparison of different injectate volumes for stellate ganglion block:an anatomic and radiologic study[J]. Reg Anesth Pain Med, 2007, 32(3):203-208.
23.	Tollision CD, Satterthwaite JR, Tollison JW. 臨床疼痛學[M]. 宋文閣, 傅志儉, 主譯. 濟南:山東科學技術出版社, 2004:82.
24.	Jung G, Kim BS, Shin KB, et al. The optimal volume of 0.2% ropivacaine required for an ultrasound-guided stellate ganglion block[J]. Korean J Anesthesiol, 2011, 60(3):179-184.
25.	Nitahara K, Dan K. Blood flow velocity changes in carotid and vertebral arteries with stellate ganglion block:measurement by magnetic resonance imaging using a direct bolus tracking method[J]. Reg Anesth Pain Med, 1999, 23(6):600-604.
26.	徐陽平, 方蘇亭, 楊功旭, 等. 星狀神經節阻滯治療椎動脈型頸椎病的效果及其機制[J]. 中國臨床康復, 2004, 8(11):2008-2009.

1. Miller RD, Pardo M. Basics of anesthesia:expert consult[M]. 6 ed.Philadelphia:Elsevier Health Sciences, 2011:709.
2. Deer TR, Leong MS, Buvanendran A, et al. Comprehensive treatment of chronic pain by medical, interventional, and integrative approaches the American academy of pain medicine textbook on patient manugement[M]. New York:Springer, 2013:349-357.
3. 張曉東. 星狀神經節阻滯的臨床應用及相關機制研究[J]. 重慶醫學, 2010, 39(19):2612-2613.
4. 金涌, 李俊, 呂雄文, 等. 甲磺酸羅哌卡因注射液的狗藥代動力學研究[J]. 安徽醫藥, 2005, 9(1):10-12.
5. 李西寬, 焦亞奇, 劉俊田, 等. 甲磺酸羅哌卡因局麻作用的實驗研究[J]. 中國藥理學通報, 2004, 20(2):236-237.
6. 徐建青, 朱波, 葉鐵虎, 等. 手術患者0.894% 甲磺酸羅哌卡因與0.75% 鹽酸羅哌卡因硬膜外麻醉的效果[J]. 中華麻醉學雜志, 2005, 25(8):624-625.
7. 鹽谷正弘. 神經阻滯圖解[M]. 熊利澤, 鄭恒興, 主譯. 西安:第四軍醫大學出版社, 2004:30.
8. Feigl G, Fuchs A, Gries M, et al. A supraomohyoidal plexus block designed to avoid complications[J]. Surg Radiol Anat, 2006, 28(4):403-408.
9. 蔣文臣, 鄭寶森. 星狀神經節阻滯[J]. 實用疼痛學雜志, 2007, 3(2):106-114.
10. 楊帆, 楊邦祥, 肖紅, 等. 初學者超聲引導下星狀神經節阻滯與傳統星狀神經節阻滯準確性與安全性比較[J]. 中國疼痛醫學雜志, 2008, 14(6):374-375.
11. Soneji N, Peng PW. Ultrasound-guided pain interventions-a review of techniques for peripheral nerves[J]. Korean J Pain, 2013, 26(2):111-124.
12. Rathmell JP. Atlas of image-guided intervention in regional anesthesia and pain medicine[M]. 2 ed. Philadelphia:Lippincott Williams & Wilkins, 2012:152-153.
13. Tafra L, Fine R, Whitworth P, et al. Prospective randomized study comparing cryo-assisted and needle-wire localization of ultrasoundvisible breast tumors[J]. Am J Surg, 2006, 192(4):462-470.
14. Nix CM, Harmon DC. Avoiding intravascular injection during ultrasound-guided stellate ganglion block[J]. Anaesthesia, 2011,66(2):134-135.
15. Rastogi S, Tripathi S. Cardiac arrest following stellate ganglion block performed under ultrasound guidance[J]. Anaesthesia, 2010, 65(10):1042.
16. 莊心良, 曾因明, 陳伯鑾. 現代麻醉學[M]. 3版. 北京:人民衛生出版社, 2003:610-611.
17. Brenda A, David R, David J, et al. 實用產科麻醉[M]. 黃宇光,主譯. 北京:人民衛生出版社, 2010:31.
18. 肖小華, 劉穎菊, 丁敏, 等. 甲磺酸羅哌卡因與鹽酸羅哌卡因的生物等效性分析[J]. 第三軍醫大學學報, 2006, 28(19):1968-1970.
19. 蔡美華, 張馬忠, 榮征星, 等. 甲磺酸羅哌卡因和鹽酸羅哌卡因硬膜外阻滯的藥代動力學特征比較[J]. 上海交通大學學報·醫學版, 2011, 31(5):584-587.
20. 景勝, 吳悅維, 包曉航, 等. 0.894% 甲磺酸羅哌卡因與0.75% 鹽酸羅哌卡因用于下腹部手術臨床觀察[J]. 重慶醫學, 2007, 36(16):1600-1601.
21. 廖志敏, 張晉峰, 張蘭, 等. 甲磺酸羅哌卡因與鹽酸羅哌卡因用于神經阻滯麻醉的臨床效果比較[J]. 四川醫學, 2007, 28(10):1128-1130.
22. Feigl GC, Rosmarin W, Stelzl A, et al. Comparison of different injectate volumes for stellate ganglion block:an anatomic and radiologic study[J]. Reg Anesth Pain Med, 2007, 32(3):203-208.
23. Tollision CD, Satterthwaite JR, Tollison JW. 臨床疼痛學[M]. 宋文閣, 傅志儉, 主譯. 濟南:山東科學技術出版社, 2004:82.
24. Jung G, Kim BS, Shin KB, et al. The optimal volume of 0.2% ropivacaine required for an ultrasound-guided stellate ganglion block[J]. Korean J Anesthesiol, 2011, 60(3):179-184.
25. Nitahara K, Dan K. Blood flow velocity changes in carotid and vertebral arteries with stellate ganglion block:measurement by magnetic resonance imaging using a direct bolus tracking method[J]. Reg Anesth Pain Med, 1999, 23(6):600-604.
26. 徐陽平, 方蘇亭, 楊功旭, 等. 星狀神經節阻滯治療椎動脈型頸椎病的效果及其機制[J]. 中國臨床康復, 2004, 8(11):2008-2009.

West China Medical Journal

Clinical Effects of Different Concentrations of Ropivacaine Mesylate on Stellate Ganglion Block

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