• 1. Children’s Hospital, Tianjin University/Tianjin Children’s Hospital, Tianjin Key Laboratory of Birth Defects for Prevention and Treatment, Tianjin 300134, P. R. China;
  • 2. School of Pharmacy, Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), Key Laboratory of Immune Microenvironment and Disease (Ministry of Education), The Province and Ministry Co-Sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University, Tianjin 300070, P. R. China;
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Pollen is a natural, renewable, and biodegradable microparticle that has demonstrated significant potential for application in the biomedical field in recent years. It features a natural core–shell structure, unique morphology, and uniform size. The sporopollenin outer layer of pollen provides exceptional chemical stability, biocompatibility, and ultraviolet-resistant. Moreover, the surface of pollen is abundant in functional groups, allowing facile chemical modification. Owing to these distinctive physicochemical properties and favorable biological characteristics, pollen has emerged as an ideal biomaterial platform. This review outlines recent advances in the biomedical applications of pollen. It introduces methods for defatting and gelation processing of pollen and systematically summarizes its applications in various fields, including drug carriers, microrobots/micromotors, biosensors, three-dimensional printing, photothermal therapy, hemostasis, biological scaffolds, and ultraviolet-resistant. This review provides a reference for broadening the application of pollen and offers insights into the utilization of natural resources.

Citation: BAI Liya, WANG Yuanyuan, YANG Liu, WANG Yinsong, SUN Yanyan. Research progress on the application of pollen in the biomedical field. Journal of Biomedical Engineering, 2026, 43(4): 872-878. doi: 10.7507/1001-5515.202511022 Copy

Copyright ? the editorial department of Journal of Biomedical Engineering of West China Medical Publisher. All rights reserved

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