Functional requirements and research advances of antimicrobial hydrogels for combat trauma wound repair_Journal of Biomedical Engineering

Authors：

WU Bianmei ¹ ,  WEI Gejin ²

1. Outpatient Clinic, Unit 95072 of the Chinese People's Liberation Army, Nanning 530020, P. R. China;
2. Department of Orthopedics, The 923rd Hospital of the Joint Logistics Support Force of the People's Liberation Army, Nanning 530022, P. R. China;

Corresponding?author：

Keywords：

Antimicrobial hydrogels; Combat trauma; Infection control; Wound repair; Echelon care

DOI：

10.7507/1001-5515.202510036

Video：

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Abstract Full text Figures/Tables Video References Cited by

Battlefield trauma wounds, characterized by complex injury mechanisms and extremely high infection risks, impose stringent multifunctional requirements on wound repair materials-specifically rapid hemostasis, potent antimicrobial activity, dynamic adhesion, and promotion of tissue regeneration. Antimicrobial hydrogels demonstrate significant advantages in infection control and tissue regeneration owing to their three-dimensional network structure, high water content, and tunable physicochemical properties. Based on the distinct requirements of each stage of the battlefield trauma echelon care system (encompassing emergency field care, medical evacuation, and definitive hospital treatment), and while fully accounting for battlefield environmental constraints, this review systematically evaluates the applicability, technical bottlenecks, and clinical translation prospects of various antimicrobial hydrogels. The analysis aims to provide a theoretical foundation and targeted research directions for the design of next-generation intelligent hydrogels optimized for battlefield application.

Citation： WU Bianmei, WEI Gejin. Functional requirements and research advances of antimicrobial hydrogels for combat trauma wound repair. Journal of Biomedical Engineering, 2026, 43(4): 879-885. doi: 10.7507/1001-5515.202510036 Copy

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