經頸外動脈路徑溶栓治療眼動脈變異患者視網膜中央動脈阻塞1例_Chinese Journal of Ocular Fundus Diseases

Authors：

石寒菡 , 何曉雨 , 楊潔 , 范佳燕 , 陸琳娜 ,  文旭洋

上海交通大學醫學院附屬第九人民醫院眼科視覺健康全國重點實驗室上海市眼眶病眼腫瘤重點實驗室, 上海 200011;

Corresponding?author：

文旭洋, Email: 86902497@qq.com

Keywords：

視網膜中央動脈阻塞; 超選擇性眼動脈介入溶栓; 頸外動脈; 病例報告

DOI：

10.3760/cma.j.cn511434-20250926-00418

Video：

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Citation： 石寒菡, 何曉雨, 楊潔, 范佳燕, 陸琳娜, 文旭洋. 經頸外動脈路徑溶栓治療眼動脈變異患者視網膜中央動脈阻塞1例. Chinese Journal of Ocular Fundus Diseases, 2026, 42(9): 789-791. doi: 10.3760/cma.j.cn511434-20250926-00418 Copy

1.	Mac Grory B, Schrag M, Biousse V, et al. Management of central retinal artery occlusion: a scientific statement from the American Heart Association[J/OL]. Stroke, 2021, 52(6): e282-e294[2021-04-08]. https://pubmed.ncbi.nlm.nih.gov/33677974/. DOI: 10.1161/STR.0000000000000366.
2.	Schrag M, Youn T, Schindler J, et al. Intravenous fibrinolytic therapy in central retinal artery occlusion: a patient-level meta-analysis[J]. JAMA Neurol, 2015, 72(10): 1148-1154. DOI: 10.1001/jamaneurol.2015.1578.
3.	Beatty S, Au Eong KG. Local intra-arterial fibrinolysis for acute occlusion of the central retinal artery: a meta-analysis of the published data[J]. Br J Ophthalmol, 2000, 84(8): 914-916. DOI: 10.1136/bjo.84.8.914.
4.	Schmidt DP, Schulte-Monting J, Schumacher M. Prognosis of central retinal artery occlusion: local intraarterial fibrinolysis versus conservative treatment[J]. AJNR Am J Neuroradiol, 2002, 23(8): 1301-1307.
5.	Schumacher M, Schmidt D, Wakhloo AK. Intra-arterial fibrinolysis in central artery occlusion[J]. Radiologe, 1991, 31(5): 240-243.
6.	Hayreh SS. Acute retinal arterial occlusive disorders[J]. Prog Retin Eye Res, 2011, 30(5): 359-394. DOI: 10.1016/j.preteyeres.2011.05.001.
7.	McLeod D, Beatty S. Evidence for an enduring ischaemic penumbra following central retinal artery occlusion, with implications for fibrinolytic therapy[J]. Prog Retin Eye Res, 2015, 49: 82-119. DOI: 10.1016/j.preteyeres.2015.06.001.
8.	Bonasia S, Bojanowski M, Robert T. Embryology and anatomical variations of the ophthalmic artery[J]. Neuroradiology, 2020, 62(2): 139-152. DOI: 10.1007/s00234-019-02336-4.
9.	Hayreh SS. Orbital vascular anatomy[J]. Eye (Lond), 2006, 20(10): 1130-1144. DOI: 10.1038/sj.eye.6702377.
10.	Michalinos A, Zogana S, Kotsiomitis E, et al. Anatomy of the ophthalmic artery: a review concerning its modern surgical and clinical applications[J/OL]. Anat Res Int, 2015, 2015: 591961[2015-11-09]. https://pubmed.ncbi.nlm.nih.gov/26635976/. DOI: 10.1155/2015/591961.
11.	Yi Z, Sasaki T, Satoh D, et al. Carotid-anterior cerebral artery anastomosis associated with paraclinoid aneurysm and ophthalmic artery originating from middle meningeal artery: case report and consideration of terminology[J/OL]. World Neurosurg, 2016, 88: e1-e4[2015-11-23]. https://pubmed.ncbi.nlm.nih.gov/26615789/. DOI: 10.1016/j.wneu.2015.11.021.
12.	Honma Y, Ogawa T, Nagao S. Angiographically occult anomalous ophthalmic artery arising from the anterior cerebral artery[J]. Acta Neurochir (Wien), 1997, 139(5): 480-481. DOI: 10.1007/BF01808888.
13.	Sade B, Tampieri D, Mohr G. Ophthalmic artery originating from basilar artery: a rare variant[J]. AJNR Am J Neuroradiol, 2004, 25(10): 1730-1731.
14.	Ogul H. Double ophthalmic arteries arising from the internal carotid artery and the accessory meningeal artery: a case report of a new anatomic variation[J]. World Neurosurg, 2020, 135: 103-106. DOI: 10.1016/j.wneu.2019.12.016.
15.	G?ko?lu A, Yi?it H, Inan E, et al. Ophthalmic artery originating from anterior inferior cerebellar artery: a rare variation[J]. Surg Radiol Anat, 2024, 46(12): 1955-1958. DOI: 10.1007/s00276-024-03500-z.
16.	Bertelli E, Leonini S, Galimberti D, et al. Hemodynamic and anatomic variations require an adaptable approach during intra-arterial chemotherapy for intraocular retinoblastoma: alternative routes, strategies, and follow-up[J]. AJNR Am J Neuroradiol, 2016, 37(7): 1289-1295. DOI: 10.3174/ajnr.A4741.

1. Mac Grory B, Schrag M, Biousse V, et al. Management of central retinal artery occlusion: a scientific statement from the American Heart Association[J/OL]. Stroke, 2021, 52(6): e282-e294[2021-04-08]. https://pubmed.ncbi.nlm.nih.gov/33677974/. DOI: 10.1161/STR.0000000000000366.
2. Schrag M, Youn T, Schindler J, et al. Intravenous fibrinolytic therapy in central retinal artery occlusion: a patient-level meta-analysis[J]. JAMA Neurol, 2015, 72(10): 1148-1154. DOI: 10.1001/jamaneurol.2015.1578.
3. Beatty S, Au Eong KG. Local intra-arterial fibrinolysis for acute occlusion of the central retinal artery: a meta-analysis of the published data[J]. Br J Ophthalmol, 2000, 84(8): 914-916. DOI: 10.1136/bjo.84.8.914.
4. Schmidt DP, Schulte-Monting J, Schumacher M. Prognosis of central retinal artery occlusion: local intraarterial fibrinolysis versus conservative treatment[J]. AJNR Am J Neuroradiol, 2002, 23(8): 1301-1307.
5. Schumacher M, Schmidt D, Wakhloo AK. Intra-arterial fibrinolysis in central artery occlusion[J]. Radiologe, 1991, 31(5): 240-243.
6. Hayreh SS. Acute retinal arterial occlusive disorders[J]. Prog Retin Eye Res, 2011, 30(5): 359-394. DOI: 10.1016/j.preteyeres.2011.05.001.
7. McLeod D, Beatty S. Evidence for an enduring ischaemic penumbra following central retinal artery occlusion, with implications for fibrinolytic therapy[J]. Prog Retin Eye Res, 2015, 49: 82-119. DOI: 10.1016/j.preteyeres.2015.06.001.
8. Bonasia S, Bojanowski M, Robert T. Embryology and anatomical variations of the ophthalmic artery[J]. Neuroradiology, 2020, 62(2): 139-152. DOI: 10.1007/s00234-019-02336-4.
9. Hayreh SS. Orbital vascular anatomy[J]. Eye (Lond), 2006, 20(10): 1130-1144. DOI: 10.1038/sj.eye.6702377.
10. Michalinos A, Zogana S, Kotsiomitis E, et al. Anatomy of the ophthalmic artery: a review concerning its modern surgical and clinical applications[J/OL]. Anat Res Int, 2015, 2015: 591961[2015-11-09]. https://pubmed.ncbi.nlm.nih.gov/26635976/. DOI: 10.1155/2015/591961.
11. Yi Z, Sasaki T, Satoh D, et al. Carotid-anterior cerebral artery anastomosis associated with paraclinoid aneurysm and ophthalmic artery originating from middle meningeal artery: case report and consideration of terminology[J/OL]. World Neurosurg, 2016, 88: e1-e4[2015-11-23]. https://pubmed.ncbi.nlm.nih.gov/26615789/. DOI: 10.1016/j.wneu.2015.11.021.
12. Honma Y, Ogawa T, Nagao S. Angiographically occult anomalous ophthalmic artery arising from the anterior cerebral artery[J]. Acta Neurochir (Wien), 1997, 139(5): 480-481. DOI: 10.1007/BF01808888.
13. Sade B, Tampieri D, Mohr G. Ophthalmic artery originating from basilar artery: a rare variant[J]. AJNR Am J Neuroradiol, 2004, 25(10): 1730-1731.
14. Ogul H. Double ophthalmic arteries arising from the internal carotid artery and the accessory meningeal artery: a case report of a new anatomic variation[J]. World Neurosurg, 2020, 135: 103-106. DOI: 10.1016/j.wneu.2019.12.016.
15. G?ko?lu A, Yi?it H, Inan E, et al. Ophthalmic artery originating from anterior inferior cerebellar artery: a rare variation[J]. Surg Radiol Anat, 2024, 46(12): 1955-1958. DOI: 10.1007/s00276-024-03500-z.
16. Bertelli E, Leonini S, Galimberti D, et al. Hemodynamic and anatomic variations require an adaptable approach during intra-arterial chemotherapy for intraocular retinoblastoma: alternative routes, strategies, and follow-up[J]. AJNR Am J Neuroradiol, 2016, 37(7): 1289-1295. DOI: 10.3174/ajnr.A4741.

Chinese Journal of Ocular Fundus Diseases

經頸外動脈路徑溶栓治療眼動脈變異患者視網膜中央動脈阻塞1例

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