In October 2025, the American Heart Association and American Academy of Pediatrics released the “2025 American Heart Association and American Academy of Pediatrics Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care”, which systematically revised the 2025 version guideline based on evidence-based medicine, comprehensively updated the recommended content, class (strength) of recommendation, and level (quality) of evidence, and provided the latest recommendations aimed at improving survival rates and neurological outcomes after cardiac arrest. Since 2020, the Cardiology Committee of American Heart Association has strengthened its collaboration with the American Academy of Pediatrics to jointly publish and cochair the writing groups for neonatal resuscitation, pediatric basic life support, and pediatric advanced life support. This article mainly interprets the recommended content for updating neonatal resuscitation, pediatric basic life support, and pediatric advanced life support, in order to better guide emergency personnel and improve the quality of cardiopulmonary resuscitation and cardiovascular emergency care.