This article interprets the 2025 International Wound Infection Institute consensus Therapeutic Wound and Skin Cleansing: Clinical Evidence and Recommendations, which marks a paradigm shift in viewing wound cleansing as a “core therapy” rather than an “ancillary procedure”. It systematically analyzes the definition of “therapeutic wound cleansing”, clarifies its distinction from debridement, and explains the proposed “optimal wound care” theoretical model. The core content involves an evidence-based interpretation and comparative analysis of the 14 recommendations across 5 dimensions: timing/frequency, scope, technique/operational standards, solution selection, and pain management. Finally, considering the current state of clinical practice in China, the article discusses the consensus’s implications for promoting standardized and precise wound care, and suggests directions for future research.
Objective To evaluate and summarize the relevant evidence of oxygenation strategies with tracheal intubation after extubation for adult in intensive care unit (ICU), and to provide evidence-based practice for the development of scientific and effective strategies tracheal intubation after extubation for ICU adult patients. Methods Evidence-based databases, related guideline websites, association websites and original databases were searched by computer for literature about oxygenation strategies with tracheal intubation after extubation for ICU adults patients was extracted. The retrieval time was from the establishment of the databases to May 2023. Two researchers trained in evidence-based practice evaluated the quality of the included literature and extracted evidence from the literature that met the quality evaluation criteria. Results A total of 18 articles were included, including 7 guidelines, 4 clinical decisions, 2 expert consensus, 4 systematic reviews and 1 randomized controlled trial. A total of 22 pieces of best evidence were formed, including 7 aspects of basic principles, evaluation, selection, parameter setting, withdrawal, effect evaluation and precautions. ConclusionThe medical staff should select the best evidence based on the actual clinical situation and the patient’s own needs, and adjust the oxygenation strategies to reduce the rate of tracheal intubation and improve the prognosis of patients.