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"cerebral trauma" 2 results
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摘要:目的:探討5·12汶川8.0級地震中顱面部外傷的影像學表現特點。方法: 回顧性分析自2008年5月12~31日因地震顱面部外傷在我院行CT、MRI檢查的傷員251例,其中CT檢查248例,MRI檢查16例。結果:放射檢查陽性162例,陽性率為64.54%,以40～49歲年齡組最多,為53例,其中男性41例。在放射檢查陽性中,多發傷112例(約69.13%),多類型顱面部外傷同時并存103例(約63.58%)。主要損傷發生率依次為軟組織損傷(35.50%),骨折(22.94%),腦挫裂傷(21.21%),硬膜下及硬膜外血腫(10.40%),其它(共約9.92%)。結論: 地震造成顱面部外傷人群主要為40～49歲中年男性,多發傷、多類型顱面部外傷多見,并以軟組織損傷、骨折、腦挫裂傷、硬膜下及硬膜外血腫較常見。Abstract: Objective: To describe the imaging features of head and face injured patients after the Wenchuan earthquake. Methods: The radiological information of 251 victims who were suspicious of head and face injury and underwent CT or MRI examinations from 12 May to 31 May 2008 was analysed retrospectively. There were 248 and 16 cases underwent CT or MRI examinations respectively. Results: One hundred and sixtytwo cases(64.54% )were positive. There were 53 cases in the 4049 years old age group, of which 41 were male. In patients with positive findings, 112 cases (about 63.58%) were comprised of several types of head and face injury. The incidence of the main injury type included: soft tissue injury (35.50%), fracture (22.94%), cerebral contusion (21.21%), subdural and epidural hematoma (12.40%), others (9.92%). Conclusions: The males with head and face injury in 4049 years old group were the major injured people in this earthquake. Head and face injury accompanied by multiple system injuries, the existence of several types of head and face injury at the same time were common. Among all the injury types, soft tissue injury, fracture, contusion, subdural and epidural hematoma were relatively commom.
Release date：2016-08-26 03:57
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Objective To observe whether the animal model of optic nerve injury in rats can be set up by fluid percussion brain injury device (FPI) or not.Methods Seventyone healthy female Wister rats were randomly divided into 2 groups, inlcuding model group with 66 rats and control group with 5 rats.The rats in model group were randomly divided into 3 groups. Eight rats in group 1 were examined by flashvisual evoked potential (F-VEP) and magnetic resonance imaging (MRI) examines before and 1, 3 days,1,2,4,6,and 8 weeks after injury; 56 rats in group 2 were randomly divided into 7 subgroups with 8 rats in each subgroup，and were detected by histopathological and terminal deoxynucleotidyl transferasemediated dUTP nick end labeling (TUNEL) apoptosis examines 1, 3 days, 1,2,4,6,8 weeks after injury；2 rats in group 3 were examined by electron microscopy 4 and 8 weeks after injury.According to the degree of injury, the injured eyes were divided into 2 groups including severe injury group with the beat pressure of （699.14plusmn;60.79） kPa and mild injury group with the beat pressure of （243.18plusmn;20.26） kPa.The right and left eyes in rats in each group were in severe and mild injury group, respectively.Results One day after injury, the latency duration of FVEP prolonged in severe injury group，wich differed much form which in the normal control group (P＜0.05)；the amplitude was gradually reduced during the first 2 weeks after injury and kept steady after that (P＞0.05). The latency duration prolonged in mild injury group,and its difference with the normal control group was statistically significant (P＜0.05)；the amplitude was gradually reduced during the first 4 weeks after injury and kept steady after that (P＞0.05). The abnormal high signal could be seen on optic nerve 1 day after injury, and was still obvious 8 weeks later. The results of histopathological examination showed ruptured capillary in ganglion cell layer 1 day after injury;retinal ganglion cells without nucleus could be seen 4 weeks after injury. The apoptosis of positive cells was found in each layer of the retina 3 days after injury.TUNEL results indicated that the number of apoptotic positive cells increased significantly 1-2 weeks after injury.Conclusion An animal model of optic nerve injury can be successfully set up using FPI in rats.
Release date：2016-09-02 05:42
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