目的:觀察A型肉毒毒素(BTXA)對面肌痙攣(HFS)患者痙攣程度的改善和生存質量的影響。方法: 對68例HFS患者進行局部注射BTXA,治療前及治療后1個月分別對患者的痙攣程度進行判定和使用世界衛生組織生存質量評定量表簡表(WHOQOL-BREF)評價生存質量。 結果: 97.04%的HFS患者在BXTA治療后1個月痙攣明顯改善緩解,而且患者在WHOQOL-BREF的生理領域、心理領域、社會關系領域、總的健康狀況和總的生存質量的評分均明顯高于治療前,差異有統計學意義(Plt;0.01)。 結論: 局部注射BTXA可迅速緩解或消除HFS患者肌肉痙攣,提高患者的生存質量。
To address the issues of time-consuming manual tooth alignment, reliance on physician experience, and insufficient structural constraints in automated methods in traditional orthodontic treatment planning, this paper proposes an automated tooth alignment network model that integrates multi-source geometric information learning. First, this study uses tooth mesh data as input to construct a graph convolution-based network for extracting tooth geometric features, fully utilizing the topological connectivity and local geometric features of the tooth model to enhance the extraction of tooth morphological features. Then, an arch line prediction network is designed to guide the teeth to align orderly along the natural arch line by explicitly modeling the tooth alignment trajectory, thereby ensuring the anatomical rationality and aesthetics of the overall structure. Based on this, this study designs collision avoidance loss and arch alignment loss to reduce geometric conflicts between adjacent teeth and constrain the overall posture, making the alignment results more stable and realistic. To verify the effectiveness of the method, validation experiments were conducted on multiple sets of real dental arch data, and comparisons were made with mainstream methods such as tooth alignment network (TaligNet), parameterized spatial transformation network (PSTN), and Transformer-based network for tooth alignment (TANet). The results show that the proposed method improves the evaluation metrics to varying degrees, fully integrates global and local geometric information, improves tooth posture coordination and alignment smoothness, and provides efficient and standardized intelligent support for digital orthodontic treatment planning.
Objective We aimed to evaluate the current status of the construction and practice of the stroke center in West China Hospital of Sichuan University and develope a future strategy to promote the standardized developement of inpatients care and evidence practice. Methods The current status of the Stroke Center in West China Hospital of Sichuan University was assessed. The procedure of diagnosis and treatment was inspected in detail, including triage, thrombolytic therapy, antithrombotic medication and anticoagulant, primary and secondary prevention, filter of risk factors, rehabilitation and education for patients. After that, new plans were made on the basis of the assessment and experiences acquired from practices in the Stroke Center in West China Hospital. Results The primary Stroke Center had been constructed in West China Hospital. The practice in West China Hospital showed that the Stroke Center significantly reduced the mortality and shortened the length of hospital stay of the patients with stroke. Conclusion It is proved that construction and implementation of the Stroke Center in West China Hospital are feasible.