ObjectiveTo summarize the research progress of surgical technique and immunosuppressive regimen of abdominal wall vascularized composite allograft transplantation in animals and clinical practice. MethodsThe literature on abdominal wall transplantation at home and abroad in recent years was extensively reviewed and analyzed. ResultsThis review includes animal and clinical studies. In animal studies, partial or total full-thickness abdominal wall transplantation models have been successfully established by researchers. Also, the use of thoracolumbar nerves has been described as an important method for functional reconstruction and prevention of long-term muscle atrophy in allogeneic abdominal wall transplantation. In clinical studies, researchers have utilized four revascularization techniques to perform abdominal wall transplantation, which has a high survival rate and a low incidence of complications. ConclusionAbdominal wall allotransplantation is a critical reconstructive option for the difficulty closure of complex abdominal wall defects. Realizing the recanalization of the nerve in transplanted abdominal wall to the recipient is very important for the functional recovery of the allograft. The developments of similar research are beneficial for the progress of abdominal wall allotransplantation.
目的 探討4種輸尿管鏡入鏡方法的成功率及對輸尿管口的損傷。 方法 回顧性分析2008年7月－2011年3月間行輸尿管鏡手術的患者共553例，按其入鏡方法分為4組，分別采用球囊擴張法、灌注泵加壓灌注入鏡法、內旋法及倒入法進行輸尿管鏡操作。分析其成功率及對輸尿管口的損傷。 結果 氣囊擴張法成功率為95%，但對輸尿管口的損傷率為100%；灌注泵加壓法成功率為67.5%，輸尿管口損傷率為87.0%；內旋法的成功率為87.9%，損傷率為50.0%；倒入法成功率91.0%，對輸尿管口損傷率為22.2%。4種方法中，灌注泵加壓法一次性成功率最低，與其余3種方法比較，差異均有統計學意義（P＜0.008）；其余3種方法間一次性成功率差異無統計學意義（P＞0.008）。對輸尿管口的損傷率，4種方法組間兩兩比較的差異均有統計學意義（P＜0.008），其中氣囊擴張法損傷率最高，倒入法最低。 結論 倒入法是4種方法中成功率較高且損傷小的一種方法。
Objective To investigate the effectiveness of a healthcare consortium combined with an internet-based medical model in the management of epilepsy centers in ethnic minority regions, and to provide guidance for the standardized management of epilepsy in these areas. Methods This was a prospective cohort study. A total of 300 epilepsy patients admitted to the Epilepsy Center of Liangshan Yi Autonomous Prefecture from January to December 2025 were selected and divided into an observation group (150 patients) and a control group (150 patients) based on whether they were included in the medical consortium plus internet-based healthcare management model. The observation group was managed using the integrated medical consortium and internet-based healthcare model, while the control group received traditional management. We compared baseline data comparability, clinical efficiency indicators (waiting time for consultation, length of hospital stay, follow-up compliance rate), efficacy indicators (seizure frequency, overall response rate), safety indicators (complication incidence rate), cognitive function (MMSE score), and quality of life (QOLIE-31 score) between the two groups. Results There were no statistically significant differences between the two groups in terms of age, gender, ethnic composition, disease duration, seizure type, baseline seizure frequency, or baseline MMSE scores (P>0.05), indicating comparability. After 6 months of intervention, the monthly seizure frequency in the observation group decreased from the baseline (6.51±1.02) to (2.34±0.89), while that in the control group decreased from (6.48±0.98) to (4.12±1.15); the difference between the groups was statistically significant (P<0.05); The overall response rate was 92.00% (138/150) in the observation group and 76.00% (114/150) in the control group, with a statistically significant difference (χ2=14.286, P=0.001). The mean waiting time for outpatient visits in the observation group was (3.12±1.05) days, which was shorter than that of the control group (7.24±2.15) days (t=11.365, P<0.001); The average length of hospital stay was (7.24±2.18) days, shorter than that of the control group (10.56±3.24) days (t=5.892, P<0.001). The outpatient follow-up compliance rate in the observation group was 90.00% (135/150), higher than the 68.00% (102/150) in the control group (χ2=8.362, P=0.004). The improvement in MMSE scores in the observation group was (9.74±3.45) points, which was superior to that of the control group (5.74±2.89) points (t=7.234, P<0.001); The improvement in QOLIE-31 total scores was (18.45±6.23) points and (11.24±5.67) points, respectively, with a statistically significant difference (t=6.891, P<0.001). Patient satisfaction in the observation group was 94.00% (141/150), higher than the 80.00% (120/150) in the control group (χ2=4.332, P=0.037). Conclusion The integrated medical consortium and internet-based healthcare model can optimize the diagnosis and treatment process for epilepsy patients in ethnic minority regions, reduce seizure frequency, improve cognitive function and quality of life, and enhance the level of regional medical services.
【摘要】 目的 探討腎鏡結合氣壓彈道碎石治療膀胱結石的臨床療效。 方法 分析2004年9月－2011年3月男性膀胱結石患者87例的臨床資料。結石直徑1.5~6.7 cm，使用腎鏡結合氣壓彈道碎石術治療，統計手術時間、手術并發癥。隨訪3個月，觀察有無尿道狹窄。 結果 所有患者碎石成功，平均手術時間為37 min，無殘留結石，無膀胱穿孔、感染性休克、膀胱大出血等并發癥；術后3個月隨訪，經尿道手術者均未發現尿道狹窄。 結論 腎鏡下氣壓彈道碎石術是治療膀胱結石安全、有效的方法。【Abstract】 Objective To explore the clinical efficacy of pneumatic ballistic lithotripsy via nephroscope in treating patients with bladder stones. Methods We retrospectively analyzed the clinical data of 87 patients with bladder stones from September 2004 to March 2011. The diameter of the stones were ranged from 1.5 to 6.7 cm. The patients underwent peneumatic ballistic lithotripsy via nephroscope. We recorded the operation time and complications, and observed the incidence of urethrostenosis 3 months after the beginning of the follow-up. Results All stones were fragmented and removed successfully. The average operation time was 37 minutes. No residual stone, bladder perforation, infective shock or severe bleeding of the bladder occurred. During the 3-month follow-up, no utethrostenosis occurred. Conclusion Pneumatic ballistic lithotripsy via nephroscope is a safe and efficient technique in treating bladder stones.