ObjectiveTo understand the current status of oral frailty in older patients with colostomy, and analyze the factors affecting oral frailty. MethodsRetrospective analysis of older patients with colostomy who visited the gastroenterology outpatient department of Affiliated Provincial Hospital of Shandong First Medical University from May 2023 to December 2023 as research subjects. The questionnaire survey was conducted using the general data questionnaire, oral frailty index-8 (OFI-8), the edmonton frail scale (EFS), and the nutritional risk screening score 2002. According to the OFI-8 score, the patients were divided into oral frailty group and non-oral frailty group, and the two-classified logistic regression model was used for multi-factor analysis to explore the factors affecting the oral frailty of older patients. ResultsA total of 283 survey subjects were collected, and the incidence of oral frailty in older patients was 66.4% (188/283). Multi-factor analysis results show that old age [OR=1.181, 95% CI(1.015, 1.373), P=0.032], history of smoking [OR=2.721, 95%CI(1.122, 6.599), P=0.027], history of alcohol [OR=2.878, 95%CI(1.185, 6.991), P=0.020], dentures [OR=3.173, 95%CI(1.297, 7.759), P=0.011], postoperative oral diseases≥2 [OR=5.802, 95%CI(1.911, 17.615), P=0.002], nutritional risk [OR=2.744, 95%CI(1.033, 7.284), P=0.043], high EFS score [OR=1.823, 95% CI(1.309, 2.538), P<0.001], the type of stoma is permanent [OR=2.659, 95%CI(1.126, 6.275), P=0.026] is a risk factor for oral frailty in older patients with colostomy. ConclusionThe incidence of oral frailty in older patients with colostomy is relatively high. We should pay more attention to the patient's oral frailty, and implement precise intervention measures for high-risk factors to prevent the occurrence of oral frailty or improve the condition of oral frailty.