The Human Cell Atlas project is an international collaboration following the Human Genome Project, which aims to establish a reference map for the characterization of all human cells. Recent years, the project has brought together various different types of cell atlas, mostly focusing on the cell types of individual tissues and organs. Science published the latest research results of the Pan-tissue Human Cell Atlas on 12 May 2022, which integrates cell atlas of multiple tissues and organs in the human. It contributes to a more comprehensive understanding of disease pathogenesis, vaccine development, cell engineering, tumor immunity, and regenerative drug development.