With the increasing application of medical examination in clinical diagnosis and treatment, the contradiction between the diversified demands of medical examination and the shortage of resources has gradually become prominent, and it is extremely urgent to establish the control mechanism of medical examination. This paper summarizes the present situation of medical examination and its control mechanism, sorts out the basic conditions for establishing a medical examination control mechanism from the aspect of establishing the medical examination standards of rationality, perfecting the supervision system and promoting the reform of supporting systems, and puts forward main obstacles to establishing a medical examination control mechanism. It is expected to provide a reference policy basis for the establishment of the medical examination control mechanism, improving the rational use of medical resources, and promoting the development of medical examination.